Published on 23 Feb 2023

Study looks into links between silent strokes and pre-dementia

Preliminary findings from a five-year study by the LKCMedicine’s Dementia Research Centre have found that vascular pre-dementia resulting from silent strokes is likely to be the most common cognitive disorder here.

Of the 631 participants recruited so far by the Biomarker and Cognitive Impairment Study (BioCIS), 344 had mild cognitive impairment, or pre-dementia.

BioCIS is a landmark five-year longitudinal study led by LKCMedicine to look at what is happening to the brain at the very earliest stages of dementia and even before brain changes set in.

Preliminary findings were shared at the inaugural Cognition Awareness Day 2023 on 23 Feb to raise awareness on how common chronic diseases like high blood pressure, high cholesterol, and diabetes, can lead to dementia.

The event brought together leading experts in the field, including academics and clinicians from NTU’s LKCMedicine, Dementia Research Centre and Khoo Teck Puat Hospital.


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