An international collaboratory of research centres set up by top global universities and research institutes in Singapore to engage in cutting edge research and as a base to fosters deep collaborations between Singapore universities and their international counterparts. The CREATE initiative allows students and researchers to be jointly supervised by the partnering universities and as a hub for start-ups.  

TUM CREATE is an electromobility research project undertaken by two world-leading universities, Germany’s Technische Universität München (TUM) and Singapore’s Nanyang Technological University (NTU), funded by the National Research Foundation of Singapore. TUM CREATE is part of NRF’s Campus for Research Excellence And Technological Enterprise. At TUM CREATE over 120 scientists, researchers and engineers from more than 20 countries are working on cutting-edge research that covers topics ranging from the molecule to the megacity including areas such as: electrochemistry, electric vehicle batteries, embedded systems, air conditioning, simulation and modelling, and infrastructure. We aim to support the integration of e-vehicles into Singapore’s transportation system: Improve energy storage and energy management systems needed for electromobility. Designing new e-vehicle concepts for test-bedding innovative technologies. Developing models for optimisation towards efficient future transportation systems. Our research will help to improve Singapore’s roadways, vehicles and public transport network.

The Singapore-​ETH Centre was established in 2010 by ETH Zurich - The Swiss Federal Institute of Technology and Singapore’s National Research Foundation (NRF), as part of the NRF’s CREATE campus. As ETH Zurich's only research centre outside of Switzerland, the centre has strengthened the research capacity of ETH Zurich to develop sustainable solutions to global challenges in Switzerland, Singapore and the surrounding regions. Set in Asia, in a rapidly urbanising region, the Singapore-​ETH Centre aims to provide practical solutions to some of the most pressing challenges on urban sustainability, resilience and health through its programmes: Future Cities Laboratory (FCL), Future Resilient Systems (FRS), and Future Health Technologies (FHT).

The Cambridge Centre for Advanced Research and Education (CARES) was established in 2013 as the University of Cambridge’s first research centre outside the UK. It brings together researchers from the University of Cambridge, Nanyang Technological University and National University of Singapore to work on problems relevant to Singapore and the world at large. CARES' largest programme is the Cambridge Centre for Carbon Reduction in Chemical Technology, which commenced in 2013 when CARES opened. This is a collaborative effort involving researchers from University of Cambridge, Nanyang Technological University and National University of Singapore. A further large programme began in October 2020 - the Centre for Lifelong Learning and Individualised Cognition (CLIC). CLIC brings together researchers from University of Cambridge and NTU to focus on the neuroscience of learning.

The Berkeley Education Alliance for Research in Singapore (BEARS) center is a University of California center for research, graduate education, and innovation with the goal of achieving an international reputation. BEARS serves as an intellectual hub for interactions between UC Berkeley researchers and their counterparts from universities, polytechnics, research institutes, and industry in Singapore and Asia. Collaborations have already been established with Nanyang Technological University (NTU) and the National University of Singapore (NUS). BEARS will develop a broad network of partnerships and relationships with government agencies, universities, and industries in Singapore and in the region beyond. UC Berkeley expects the impact of BEARS to be the creation of new industry sectors in information technology, energy technologies, engineering, construction and related areas.

SHARE was established in 2016 to advance and strengthen research collaborations between Israel and Singapore. SHARE serves as an intellectual hub for research, scholarship, entrepreneurship and postgraduate/postdoctoral training, bringing together leading scientists from both countries to tackle major global challenges . It is the only international research center of The Hebrew University of Jerusalem outside of Israel. Nanomaterials for Energy and Water Management (NEW) is a joint research project between HUJ and NTU, to develop novel materials and devices for three themes: printable energy materials and devices, energy modulation and storage systems for buildings, and materials and processes for energy-water nexus. This project aims to innovate advanced materials in pushing the scientific frontiers in energy harvesting, conservation and storage and meet the energy-water nexus needs through innovative manufacturing processes.

The Singapore-MIT Alliance for Research and Technology (SMART) is a major research enterprise established by the Massachusetts Institute of Technology (MIT) in partnership with the National Research Foundation of Singapore (NRF) in 2007. SMART is the first entity in the Campus for Research Excellence and Technological Enterprise (CREATE) developed by NRF. SMART is MIT's first, and to-date only, research centre outside the United States. It is also MIT's largest international research programme. MIT faculty members have laboratories at SMART, mentor postdoctoral associates and graduate students, and collaborate with researchers from universities, research institutes and industries in Singapore and Asia.