Recent-Publications

2026

Feel free to read the most recent research publications from LKCMedicine's researchers below.

AGRAWAL, Rupesh
Artificial intelligence for clinical decision-making in retinal disorders: From screening and diagnosis to treatment and longitudinal management.

Deconstructing White Dot Syndromes-Multimodal Imaging in Uveitis (MUV) Taskforce: Report 11.

Evidence and Consensus-Based Imaging Guidelines in Ocular Toxoplasmosis Multimodal Imaging in Uveitis Task Force Report 14.

GLP-1 receptor agonists and ocular disease: Therapeutic promise, mechanistic insights and emerging safety signals.

Retinal Vascularity Index in Mild Cognitive Impairment.

Standardization of Retinal Vasculitis Terminology With Consensus Definitions From a Delphi Panel.

Transforming Systematic Reviews: Evaluating a Fine-Tuned Large Language Model for Abstract Screening in Uveitis and Retinal Vasculitis: Fine-Tuned LLM for Review Screening.

APFELBACHER, Christian
Lack of Patient and Public Involvement Reporting in Allergy Prevention Trials: The Example of Complementary Feeding.

BEST, James
Indices of obesity, malnutrition and inflammation are strong predictors of mortality in adults with type 2 diabetes: the FIELD study.

CHAMBERS, John
Publisher Correction: Translating genomic data into healthcare practice with the Singapore National Precision Medicine program.

The Development and Validation of the Food Memory Bias Test for a Large-Scale Epidemiological Study in a Multiethnic Asian Population.

CHEN, Weiqiang
Editorial Overview: Immunopathogenesis in viral disease.

CHIA, Po Ying
Flavivirus NS1 as a pivotal virulence factor and a tractable target for next-generation antivirals, vaccines, and immunodiagnostics.

CHOO, Yen
A Fully Defined GelMA-Based Matrix Allows Fine Tuning of Tissue-Relevant Biomechanical and Biochemical Cues for Organoid Culture.

CHOTIRMALL, Sanjay
Airway Mucus Plugs in Asthma and COPD: Pathobiology, Imaging, and Implications for Clinical Trials.

Phase III AIRTIVITY study design: verducatib (BI 1291583) in people with bronchiectasis.

Pseudomonas Aeruginosa Abundotypes and Interactotypes Reflect Clinical Heterogeneity in Bronchiectasis.

The frequent exacerbator phenotype in bronchiectasis revisited: Data from EMBARC registry.

To the Airway and Beyond: Introduction to an AJRCCM Special Section on Airway Disease.

CLELAND, Jennifer
Mixed-methods research in medical education: Lessons from a meta-study of methodological practice.

DALAN, Rinkoo
First-Line Dapagliflozin, Metformin, or Combination Therapy in Type 2 Diabetes: Vascular and Molecular Outcomes of a Randomised Controlled Trial.

DUAN, Hongwei
Dual Enzyme-Loading MnO2 Nanosystem for Cascade Chemodynamic Therapy With Enhanced Penetration in Superficial Tumors.

EMERY, Jon
Multicancer Detection Tests for Population-Wide Screening of Asymptomatic Individuals: A Systematic Review.

Process evaluation of a pharmacogenomic informed antidepressant prescribing intervention delivered in primary care: findings from the PRESIDE (PhaRmacogEnomicS in Depression) trial.

EMERY, Jon
The Prevalence and Risk Factors for at-Risk MASH and Advanced Liver Fibrosis in People With Metabolic Risk Factors in Primary Care.

HO, Andy
Assumptions and principles for responsible AI development and use in grief and bereavement care.

HOU, Han Wei
Label-free microfluidic small-volume blood processing for analysis of platelet activation and neutrophil-platelet aggregates.

KANDIAH, Nagaendran
Noninvasive Blood-Brain Barrier Imaging in Aging Community Cohorts.

KONG, Kong Li
A Multicentre Phase II Study of Trifluridine/Tipiracil in Recurrent/Metastatic Platinum-Resistant Nasopharyngeal Carcinomas.

LEE, Bernett
Brain defence by the extracellular matrix protein Cochlin.

Umbilical Cord-Derived Therapies for Wound Healing: A Scoping Review of Clinical and Translational Evidence.

LEE, Jimmy
Publisher Correction: Translating genomic data into healthcare practice with the Singapore National Precision Medicine program.

The Development and Validation of the Food Memory Bias Test for a Large-Scale Epidemiological Study in a Multiethnic Asian Population.

LEOW, Melvin
Epigenetics and Childhood Obesity: DNA Methylation Coordinates Environment and Gene Regulation.

Postural Instability Is Greater in Men with Type 2 Diabetes Following Exertional Heat Stress.

LIM, Jue Tao
Autodissemination stations suppress Aedes notoscriptus mosquitoes and reduce Buruli ulcer risk in urban Australia: a randomized controlled field trial.

Economic Burden of Inappropriate Antibiotic Prescribing Attributable to Dengue in Singapore.

How accurate are effective reproduction number estimates for mosquito-borne diseases in urban settings?

Impact of Wolbachia-mediated incompatible and sterile insect techniques on dengue incidence: a large-scale cluster randomised controlled trial.

LIM, Su Chi
Pathway-Specific Polygenic Risk Score and Risk of Hyperglycaemic Progression in Patients With Type 2 Diabetes.

LUO, Dahai
Flavivirus NS1 as a pivotal virulence factor and a tractable target for next-generation antivirals, vaccines, and immunodiagnostics.

Targeting conserved interaction surfaces of alphavirus nsP4 supports the rational design of live-attenuated vaccine candidates.

LYE, David
A randomized controlled trial evaluating a novel individualized treatment strategy for carbapenem-resistant Gram-negative bacteria infections.

A randomized controlled trial of cefiderocol versus standard therapy for Gram-negative bacterial bloodstream infections: Benefit and risk assessment using DOOR and generalized pairwise comparisons.

Economic Burden of Inappropriate Antibiotic Prescribing Attributable to Dengue in Singapore.

MINA, Theresia
Publisher Correction: Translating genomic data into healthcare practice with the Singapore National Precision Medicine program.

The Development and Validation of the Food Memory Bias Test for a Large-Scale Epidemiological Study in a Multiethnic Asian Population.

NGEOW, Joanne
Publisher Correction: Translating genomic data into healthcare practice with the Singapore National Precision Medicine program.

Recommendations for the diagnosis and management of neurofibromatosis type 1 in Singapore: A Delphi consensus.

RENIA, Laurent
Arthritis models for studying chikungunya virus joint inflammation.

SAHEKI, Yasunori
Cholesterol maintains the degradative capacity of lysosomes during clearance and recycling of dysfunctional mitochondria.

SHEN, Xiaotao
lagCI enables inference of temporal causal relationships from dense multi-omic time series.

MAPA: A Semantic Network Framework for Functional Module Discovery and Interpretation in Multi-Omics Data.

Per- and polyfluoroalkyl substances, seminal plasma metabolome, and sperm telomere length and mitochondrial DNA copy number: a cohort study.

SUNG, Joseph
Colorectal cancer in metabolic dysfunction-associated steatotic liver disease: an international Delphi consensus statement.

TAN, Andrew
A tri-component organoid model reveals field-cancerized fibroblasts as key drivers of LUAD recurrence and drug resistance.

Angiopoietin-like protein 4 deficiency promotes tumor immune infiltration and CD8+ T cell cytotoxic activity to inhibit tumor progression.

MAPA: A Semantic Network Framework for Functional Module Discovery and Interpretation in Multi-Omics Data.

Nanoparticles for autoimmune diseases: advancing diagnostics and therapeutic solutions.

TAN, Bryan
Economic Cost of Knee Osteoarthritis in Singapore.

TEY, Tey Hong
A double-blinded randomized controlled pilot study evaluating the efficacy of siRNA inhibiting SPARC microneedle patch versus siRNA inhibiting SPARC and IL4-RA microneedle patch in reducing scar volume.

WANG, Chuchu
MAPA: A Semantic Network Framework for Functional Module Discovery and Interpretation in Multi-Omics Data.

WONG, Sabrina
Primary Care Doctors' Perspectives and Experiences With a Chest X-Ray AI Triage Program: Qualitative Study.

WONG, Siu Ling
Author Correction: Loss of Fsr quorum sensing promotes biofilm formation and worsens outcomes in enterococcal infective endocarditis.

WONG, Siu Ling
Label-free microfluidic small-volume blood processing for analysis of platelet activation and neutrophil-platelet aggregates.

YAO, Liang
Global hospital admission and case fatality risks among patients with influenza virus infection: a systematic review and meta-analysis.

Standardization of Retinal Vasculitis Terminology With Consensus Definitions From a Delphi Panel.

YAP, Eric
Bacterial Lysis Observation Over Time Assay (BLOTS) for High-Throughput Isolation, Sequencing, and Characterization of Bacteriophages.

Phage bioinformatics tools: a review of computational approaches for bacteriophage research.

YEE SIN, Leo
Economic Burden of Inappropriate Antibiotic Prescribing Attributable to Dengue in Singapore.

The NUS-Lancet PRIME Commission: transforming pandemic readiness for equity.

YEO, Tianrong
Exteroceptive Reflex Myoclonus Triggered by Distal Nerve Stimulation in Anti-GAD65 Stiff-Person Syndrome.

YIM, Steve
Outdoor light at night, sleep disorder, and atopic diseases among children and adolescents: a cross-sectional study.

AGRAWAL, Rupesh
An autonomous multimodal AI agent for evidence-grounded ophthalmic diagnosis.

Evidence and Consensus Based Guidelines in Behçet Disease Uveitis. Multimodal imaging in Uveitis (MUV) Taskforce Report 18.

Toward Understanding Retinal Vasculitis: Definitions From an Expert Panel.

ANG, Shannon
Bidirectional longitudinal associations of family/friend social support with cognitive function in late life.

BIFANI, Pablo
First continuous in vitro culture of Plasmodium coatneyi reveals insights into barriers to human infection.

CHAMBERS, John
Translating genomic data into healthcare practice with the Singapore National Precision Medicine program.

CHEN, Peng
Spiderweb-inspired electronically conductive hygroscopic adhesive for chronic bioelectronic interface.

CHEUNG, Christine
Caveola and Its Resident Proteins, Caveolin-1 and -2, Play Critical Roles in the Pathogenesis of nAMD and PCV.

CHOTIRMALL, Sanjay
COPD and Aspergillus-a complex interaction of global health importance.

The Renaissance of Bronchiectasis.

CLELAND, Jennifer
Bounded accountability in professional resistance.

Colloquy: Opening a debate on professional resistance in medicine and medical education.

Sociotechnical Misalignments in Hospital AI System Implementation: Qualitative Case Study.

The Scale for AI Literacy in Health Care Workers: Development and Validation.

Widening access to medical school in Australia: A realist evaluation.

DALAN, Rinkoo
Cost-Effectiveness of Polygenic Risk Score-Guided Statin Therapy for Cardiovascular Disease Prevention in Singapore.

DUAN, Duan
Engineering Nonpathogenic Bacteria for Synergistic Tumor-Targeted Protein Degradation and Immunotherapy by Checkpoint-Inhibiting Nanobodies.

EMERY, Jon
Alternative diagnostic labels for melanoma in-situ: a randomised online experiment.

FAN, Xiuyi
Building a Global Research Network for Fair, Accountable, Interpretable, and Responsible AI in Emergency Care: Protocol for a FAIR-EC Study.

GOH, Wilson
The 2025 Westlake Autumn Symposium for AI Proteomics and Virtual Cell.

GRIVA, Konstadina
Cognition in menopause and the workplace: a call for global action.

In This Issue.

JANELA, Baptiste
Toll-like receptor 7 constrains efferocytosis in myocardial injury.

KUSUMBE, Anjali
Bone Lymphatic Endothelial Cells Form a Distinct Skeletal Population and Drive Skeletal Repair.

Multimodal evidence for bone lymphatics in skeletal health and repair.

LEE, Bernett
NF1 Leucine Rich Domain-Derived Extracellular Vesicles Remodel the Glioblastoma Immune Microenvironment via an ADAM17-Associated Inflammatory Program.

LEE, Jimmy
Brain structural abnormalities in treatment-resistant schizophrenia.

Local chemoarchitecture explains widespread lower cortical thickness associated with clinical high risk for psychosis.

Translating genomic data into healthcare practice with the Singapore National Precision Medicine program.

LEOW, Melvin
Branched chain and glucogenic amino acids predict brown fat recruitment and metabolic clearance in adults with overweight or obesity.

LI, Kelvin
Automated Review of Patient Records: Privacy-Preserving Large Language Models for Identifying Incident Nonarteritic Anterior Ischemic Optic Neuropathy at Scale.

LIM, Jue Tao
Risk of major-structural-birth-defects following repeat mRNA COVID-19 vaccination in the first trimester: a population-based cohort study.

Risk of new-incident mental health diagnoses following SARS-CoV-2 infection amongst children and young adults in Singapore: a retrospective cohort study.

Vertical Vaccination Against Infant Influenza Hospitalization in a Tropical Setting.

LIM, Su Chi
Distinct dietary patterns across type 2 diabetes subtypes: Insights from the SMART2D cohort.

Genome-wide DNA methylation analysis revealed epigenetic mechanism underlying end-stage renal disease.

Plasma Proteins Associated With Incident Acute Myocardial Infarction in Asians With Type 2 Diabetes.

β-hydroxybutyrate as an early predictive biomarker of diabetes remission following intensive dietary intervention.

LOH, Marie
Silencing of human HTT by targeted CRISPR/dCas9-mediated epigenetic editing.

LYE, David
Risk of major-structural-birth-defects following repeat mRNA COVID-19 vaccination in the first trimester: a population-based cohort study.

Risk of new-incident mental health diagnoses following SARS-CoV-2 infection amongst children and young adults in Singapore: a retrospective cohort study.

Vertical Vaccination Against Infant Influenza Hospitalization in a Tropical Setting.

MINA, Theresia
Translating genomic data into healthcare practice with the Singapore National Precision Medicine program.

NGEOW, JoanneClinGen variant curation interface workshops: Training variant scientists on an international platform.

Translating genomic data into healthcare practice with the Singapore National Precision Medicine program.

Updated ENIGMA recommendations for reporting germline variants in cancer susceptibility genes and their translation into twenty languages.

PETHE, Kevin
Growth-dependent tRNA Reprogramming and Codon Bias Link Translation to Metabolic State in Enterococcus faecalis.

Multipronged Cell Wall-Targeting Converts Ineffective Antibiotics into a Potent Regimen against Mycobacterium abscessus.

PU, KanyiLysosome self-sorting nanodegraders for hepatic clearance of pathogenic serum mediators.

Synthesis of radioafterglow nanoprobes for deep-tissue imaging of hydrogen peroxide.

RAMASAMY, Saravana
Multimodal evidence for bone lymphatics in skeletal health and repair.

RENIA, Laurent
First continuous in vitro culture of Plasmodium coatneyi reveals insights into barriers to human infection.

SADARANGANI, Sapna
Immunogenicity of high-dose recombinant influenza vaccine versus standard-dose egg-grown and cell-grown vaccines among frequently and infrequently vaccinated young adults in Singapore: a randomised, controlled, double-blind, single-centre, phase 4 clinical trial.

SHEN, Xiaotao
The gut microbiome organ.

TAN, Cher Heng
Developing future leaders for healthcare systems: a Singapore case study.

WANG, Yulan
Quantitative Characterization of the Serum Elemental Signatures in HBV Infection.

The gut microbiome organ.

YAP, Lynn
Spatiotemporal transcriptomics of human cardiovascular progenitors in pig hearts identifies Midkine as a positive regulator of neovascularization.

YEO, Si Yong
A machine learning approach to conglomerate multi-domain features of cardiac aging.

YEO, Tianrong
Frequency of anti-neural antibodies and autoimmune epilepsy in focal epilepsy of unknown etiology: An observational study in a Singaporean cohort.

YOUNG, BarnabyImmunogenicity of high-dose recombinant influenza vaccine versus standard-dose egg-grown and cell-grown vaccines among frequently and infrequently vaccinated young adults in Singapore: a randomised, controlled, double-blind, single-centre, phase 4 clinical trial.

ABISHEGANADEN, John
Cost-Effectiveness of Universal Low-Dose Computed Tomographic Lung Cancer Screening in Singapore.

AGRAWAL, Rupesh
Biological and Therapeutic Role of Interleukin-6 in Non-Infectious Uveitis: A Narrative Review
Dietary restriction during active cancer therapy is associated with improved treatment response: a systematic review and meta-analysis.

ALI, Yusuf
Dietary restriction during active cancer therapy is associated with improved treatment response: a systematic review and meta-analysis.

BIFANI, Pablo
Cryo-electron microscopy structure of Jabs, a bacteriophage infecting the multidrug-resistant pathogen Mycobacterium abscessus.
In vitro antimicrobial resistance properties of rifapentine and rifampicin are indistinguishable.

CHAMBERS, John
Building a Precision Health Ecosystem: Singapore's Approach to Innovation through the Clinical Implementation Pilots.

CHEN, Weiqiang
Performance evaluation of quantum support vector machine for COVID-19 biomarker analysis.

CHEW, Sing Yian
Nanoplex cluster-mediated synergistic modulation of dendritic cells and T cells amplifies tumor-specific adaptive immunity.

CHOTIRMALL, Sanjay
Comorbid diabetes disease severity and microbial changes in patients with bronchiectasis: a combined analysis of data from the EMBARC, EMBARC-India, Australian, and BE-China registries.

Diagnostic criteria for invasive pulmonary aspergillosis in COPD patients.

Safety and antimicrobial efficacy of CSL787, a novel nebulized IgG therapy, in patients with bronchiectasis: results from a randomized phase 1 trial.

The Lancet Commission on precision health: equitable, data-driven health outcomes for all.

CHOW, Angela
Identifying Distinct Antibiotic Behavioural Profiles in Singapore's General Population: A Latent Class Analysis.

CHUA, Karen
Cost-effectiveness of home-based fall detection and monitoring technologies for community-dwelling older adults: a systematic review protocol.

Motor Imagery Brain-Computer Interface (MI-BCI)-Assisted Upper Limb Neurorehabilitation for Acute Stroke During Inpatient Rehabilitation: A Prospective Feasibility Study with Economic Evaluation Protocol.

CLELAND, Jennifer
Beyond the faculty-student dyad: Disentangling the hidden factors shaping graduate HPE advising success.

Graduates from widening participation medical programs are disadvantaged on residency selection.

Optimising professional support for doctors who experience work performance issues: a realist evaluation.

Shaped by what is not seen: Confronting medical education's shadow curriculum

EMERY, Jon
Piloting a Clinical Decision Support System for Unintended Weight Loss in Primary Care: Mixed Methods Study on Early Cancer Detection.

Program Guidelines for the National Lung Cancer Screening Program: Targeted Lung Cancer Screening in High-Risk Individuals in Australia.

FAN, Xiuyi
Aligning deep learning and interpretable models for blood cell classification: A dual-model framework for explainability.

GOH, Wilson
Driving the future of proteome-based innovations: the π-HuB project.

Timing of Antiplatelet and Anticoagulant Therapy Resumption Following Gastrointestinal Bleeding: A Systematic Review and Meta-Analysis.

GRIVA, Konstadina
Medical students' perspectives on climate change, climate-health education, and professional identity: a qualitative study.

HAN, Siew Ping
Shaped by what is not seen: Confronting medical education's shadow curriculum

HO, Andy
Diabetes-related foot complications and caregiver burden: insights from a cross-sectional study in multi-ethnic Asians.

Systematic and Collaborative Approach to Learning and Educational Content Development (SCALED) for Health Apps: An Experience-Informed Conceptual Framework.

HUANG, Hen-Wei
Deployment of a cloud-based passive defecation monitoring system for continuous gut health monitoring.

HUANG, Tao
Nighttime Cold Stress and Cardiovascular Emergency Hospitalizations: A Time-Series Analysis by Sex and Age in a Subtropical City.

JANELA, Baptiste
Biological and Therapeutic Role of Interleukin-6 in Non-Infectious Uveitis: A Narrative Review

KHONG, Andy
Systematic and Collaborative Approach to Learning and Educational Content Development (SCALED) for Health Apps: An Experience-Informed Conceptual Framework.

KUIPERS, Ernst
Nighttime Cold Stress and Cardiovascular Emergency Hospitalizations: A Time-Series Analysis by Sex and Age in a Subtropical City.

KUSUMBE, Anjali
Blood and lymphatic vascular network in bone injury repair: from molecular mechanisms to therapeutic strategies.

Protocol for standardized minimally invasive mouse models of bisphosphonate-related and radiation-induced jaw osteonecrosis.

LEOW, Melvin
Evaluation of high-fat diet-induced metabolic impairments in iBAT lipid metabolism using 1H-MRS.

LIM, Jue Tao
Nighttime Cold Stress and Cardiovascular Emergency Hospitalizations: A Time-Series Analysis by Sex and Age in a Subtropical City.

Parental vaccination status and other socioeconomic determinants shaping COVID-19 vaccine uptake in children and adolescents in Singapore.

Real-world effectiveness of influenza vaccination amongst children aged under 5 in a tropical setting.

LIM, Su Chi
Clonal Hematopoiesis and Type 2 Diabetes: A Narrative Review.

Distinct epigenetic ageing patterns are associated with heterogeneity in kidney function decline in type 2 diabetes.

Prior SGLT2 Inhibitor and Metformin Use and Risk of Long COVID in Type 2 Diabetes: A Nationwide Population-Based Cohort Study.

LOH, Marie
Multi-ancestry polygenic risk scores for the prediction of type 2 diabetes and complications in diverse ancestries.

LUO, Dahai
Distinct RNA engagements define genome import and replication elongation in alphaviruses.

LYE, David
A review of the randomized clinical trial results from the Staphylococcus aureus network adaptive platform (SNAP) meticillin-susceptible (MSSA) and penicillin-susceptible (PSSA) domains and CloCeBa.

Parental vaccination status and other socioeconomic determinants shaping COVID-19 vaccine uptake in children and adolescents in Singapore.

Prior SGLT2 Inhibitor and Metformin Use and Risk of Long COVID in Type 2 Diabetes: A Nationwide Population-Based Cohort Study.

Real-world effectiveness of influenza vaccination amongst children aged under 5 in a tropical setting.

Utilising digital contact tracing during a pandemic to measure contact trends by risk group.

MANSKI-NANKERVIS, Jo-Anne
Cost-effectiveness of targeted COPD case-finding with the PUMA questionnaire followed by spirometry among ever-smokers in Singapore.

Piloting a Clinical Decision Support System for Unintended Weight Loss in Primary Care: Mixed Methods Study on Early Cancer Detection.

MESQUITA, Francisco S
Dynamic S-acylation controls CMG2 maturation extracellular matrix regulation and anthrax toxin susceptibility in vivo.

NAIR, Aditya
A cortical-hypothalamic neural circuit for compulsive eating in mice.

The Representation of Affective Internal States in the Hypothalamus: A Neural Manifold View.

NGEOW, Joanne
BRCA1-mutant thymoma and the role of PARP inhibitors: a case report.

Building a Precision Health Ecosystem: Singapore's Approach to Innovation through the Clinical Implementation Pilots.

Effect of Self-Sampling HPV DNA Testing on Cervical Cancer Screening in Singapore's Primary Care: Pragmatic Randomized Controlled Trial.

NGUYEN, Michele
Nighttime Cold Stress and Cardiovascular Emergency Hospitalizations: A Time-Series Analysis by Sex and Age in a Subtropical City.

PARK, Seung-Min
Deployment of a cloud-based passive defecation monitoring system for continuous gut health monitoring.

PAVESI, Andrea
CAR T cells secreting anti-EpCAM bispecific T cell engagers overcome tumor heterogeneity in targeting epithelial-originated carcinomas.

RAMADAN, Kristijan
Forging New Pathways in Oncology: Strategic Insights from the 17th Annual Frontiers in Cancer Science Conference.

Nucleophagy as an emerging therapeutic vulnerability in cancer.

RUTTER, Guy
Pancreatic α-cells integrate immune and neuronal stimuli for insulin secretion.

SHEN, Xiaotao
Deployment of a cloud-based passive defecation monitoring system for continuous gut health monitoring.

Integrated intraocular-plasma proteomics reveals conserved biomarkers for diabetic retinopathy progression: a multi-fluid biopsy study.

SUBRAMANIAM, Mythily
From diagnosis to daily life: a qualitative investigation into patients' lived experiences of pre-diabetes diagnosis and care in a primary care setting in Singapore.

SUNG, Joseph
A S.C.O.R.E. framework for evaluating open-ended responses from large language models in healthcare.

Nighttime Cold Stress and Cardiovascular Emergency Hospitalizations: A Time-Series Analysis by Sex and Age in a Subtropical City.

Timing of Antiplatelet and Anticoagulant Therapy Resumption Following Gastrointestinal Bleeding: A Systematic Review and Meta-Analysis.

TAN, Andrew
Interrupting glioblastoma malignant circuitry: plasticity traps, synaptic blockade, and myeloid reprogramming.

TIEW, Pei Yee
Diagnostic criteria for invasive pulmonary aspergillosis in COPD patients.

VAN STEENSEL, Maurice
From pixels to pimples.

Primary extramammary Paget disease of the male genitalia with very late (11-year) recurrence.

VERMA, Navin
AI-Driven Multi-Omics Integrated Applications Using Diverse Neural Networks for Breast Cancer Diagnostic Screening and Biomarker Discovery.

IFNγ priming enables NLRP3 inflammasome activation in human keratinocytes in vitro.

WANG, Yulan
Spatially-guided metabolomics profiling of metabolic regions in human tumor tissues.

WONG, Sabrina
Effect of Self-Sampling HPV DNA Testing on Cervical Cancer Screening in Singapore's Primary Care: Pragmatic Randomized Controlled Trial.

WONG, Sunny
Deployment of a cloud-based passive defecation monitoring system for continuous gut health monitoring.

Dietary restriction during active cancer therapy is associated with improved treatment response: a systematic review and meta-analysis.

Following Ariadne's thread through microbiome-based biomarker discovery in CRC.

Gut Microbiome in Depression with and without REM Sleep Behavior Disorder.

XIA, Yun
IFNγ priming enables NLRP3 inflammasome activation in human keratinocytes in vitro.

YAO, Liang
Should Risk of Bias Be Assessed at the Outcome Level?

YAP, Eric
IFNγ priming enables NLRP3 inflammasome activation in human keratinocytes in vitro.

YEO, Si Yong
A Blueprint for Agentic Workflow Support in Dynamic SPECT Myocardial Perfusion Imaging.

YEO, Tsin Wen
Urinary suPAR and NGAL as biomarkers of disease severity in hospitalized adults with community-acquired pneumonia.

YIM, Steve
Nighttime Cold Stress and Cardiovascular Emergency Hospitalizations: A Time-Series Analysis by Sex and Age in a Subtropical City.

ZHONG, Franklin
IFNγ priming enables NLRP3 inflammasome activation in human keratinocytes in vitro.

ALI, Yusuf
Implications of microplastics as emerging endocrine disruptors.

AGRAWAL, Rupesh
EyeRAG: graph retrieval-augmented generation for safe and accurate clinical dialogue in ophthalmology.
Evidence and Consensus Based Guidelines for Imaging in Tubercular Choroiditis. Multimodal imaging in Uveitis (MUV) Taskforce: Report 17.

CHAN, Alvin
The Use of Deep Learning in RNA Therapeutic Development.
Oesophageal tissue screening system for assessing the retention and mucosal absorption of biologics.

CHOTIRMALL, Sanjay
Targeting Inflammation in Bronchiectasis.
Azurocidin-1 as a mediator of bronchiectasis severity, epithelial defence, and target of dipeptidyl peptidase-1 inhibition: an international, multicohort study.
Airway Mucus Plugs in Asthma and COPD: Pathobiology, Imaging, and Implications for Clinical Trials.
The frequent exacerbator phenotype in bronchiectasis revisited: Data from EMBARC registry.

CZARNY, Bertrand
Peptide coacervate-mediated siRNA delivery for dual PD-1/PD-L1 blockade to enhance colorectal cancer immunotherapy.

CHAMBERS, John
Genomic landscape of drug binding and pharmacogenetic variation across diverse populations using SNPdrug3D.

LEE, Bernett
Blood and brain tissue RNA transcriptomics reveal six potential targets of Parkinson's disease: a meta-analysis.

LIM, Kah Leong
Lysosome-Acidifying Nanoparticles Rescue A30P α-Synuclein Induced Neuronal Death in Cellular and Drosophila Models of Parkinson's Disease.

LUO Dahai
DDX6 induces immunosuppression in cancer by disrupting structural stability of endogenous double-stranded RNAs.
A self-amplifying RNA vector based on rubella virus for mRNA therapeutics and vaccine applications.

LYE, David 
Cefazolin for Methicillin-Susceptible Staphylococcus aureus Bacteremia.

LOH, Marie
Genomic landscape of drug binding and pharmacogenetic variation across diverse populations using SNPdrug3D.

NGEOW, Joanne
Genomic landscape of drug binding and pharmacogenetic variation across diverse populations using SNPdrug3D.
Deep learning analysis of breast cancer histology predicts ATM pathogenic variant carrier status.

PAVESI, Andrea
Microfluidic technologies for extracellular vesicle isolation and analysis: Implications for translational applications in cancer therapy.

PU, Kanyi
Burst-Mode Near-Infrared Chemiluminescent Probes for In Vivo Imaging.

RAMASAMY, Saravana
Implications of microplastics as emerging endocrine disruptors.

RAMADAN, Kristijan
Nucleophagy removes cytotoxic trapped PARP1.

SUNG, Joseph
Implications of microplastics as emerging endocrine disruptors.
A S.C.O.R.E. framework for evaluating open-ended responses from large language models in healthcare.
Deployment and clearance of microrobots for localized therapy: past, present and future.

TAN, Cher Heng
MRI-based prediction of very early recurrence within 1 year after resection of HCC: An international cohort study.

WUESTEFELD, Torsten 
Implications of microplastics as emerging endocrine disruptors.

YIM, Steve
Global supply chain relocation reshaped PM2.5 pollution and human health risks.

AGRAWAL, Rupesh
Rethinking scale in ophthalmic artificial intelligence: from bigger models to smarter clinical reasoning.
Evidence and Consensus-Based Imaging Guidelines in Cytomegalovirus Retinitis: Multimodal Imaging in Uveitis (MUV) Task Force - Report 15.
Evidence and Consensus-Based Guidelines in Vogt-Koyanagi-Harada Disease. Multimodal Imaging in Uveitis (MUV) Taskforce Report 16.

CARNEY, Tom
Measuring morphogen transport over multiple spatial scales in live zebrafish embryos.

CHEN, Daisy
A Competency Framework for Medical AI Education: Mixed Methods Study.

CHEW, Sing Yian
Ion-shielding ultrathin encapsulation with hot-press bonded interface enables chronic stretchable bioelectronics.

CHEUNG, Christine
Angptl4 integrates dietary and microbial signals to disrupt gut barrier function in MASH.

CHOTIRMALL, Sanjay
Mucoactive therapies and the European Respiratory Society guideline for adult bronchiectasis: what now after the CLEAR trial?
The Lancet Commission on precision health: equitable, data-driven health outcomes for all.

FAN, Xiuyi
A Competency Framework for Medical AI Education: Mixed Methods Study.

GOH, Wilson
Examining developer perspectives on medical AI regulatory frameworks.

HOU, Han Wei
From hotspots to hotspaces: Cascaded photonic-plasmonic coupling for SERS-based deep profiling of whole small extracellular vesicles.

KASAHARA, Kazuyuki
Angptl4 integrates dietary and microbial signals to disrupt gut barrier function in MASH.
Gut microbiota modulation of regulatory DNA elements revealed by massively parallel functional characterization.

KUSUMBE, Anjali
From complexity to clarity: aging bone marrow niche in bone and blood regeneration and malignancy.

LEE, Bernett
A Competency Framework for Medical AI Education: Mixed Methods Study.

LEOW, Melvin
Epigenetics and Childhood Obesity: DNA Methylation Coordinates Environment and Gene Regulation.

LING, Xing Yi
From hotspots to hotspaces: Cascaded photonic-plasmonic coupling for SERS-based deep profiling of whole small extracellular vesicles.

PAVESI, Andrea
DK4/6 inhibition uncovers subtype-specific vulnerabilities and immune-related responses in esophageal squamous cell carcinoma.

NG, Olivia
A Competency Framework for Medical AI Education: Mixed Methods Study.

O LWIN, May
Examining developer perspectives on medical AI regulatory frameworks.

PU, Kanyi
Molecular rotor-based probes for protein monitoring in biomedical research.

RAMASAMY, Saravana
From complexity to clarity: aging bone marrow niche in bone and blood regeneration and malignancy.

SUNG, Joseph
Examining developer perspectives on medical AI regulatory frameworks.
Microswarm bridging effect for dual-surface biofilm eradication in submillimeter infection pockets.
Ultrasound-sensitive microrobotic sensor with robust anchoring for long-term digestive lesion assessment.
Comprehensive microbiome profiling reveals mucosal microbiome heterogeneity in patients with left- and right-sided colorectal neoplasia.

SCHUSTER, Stephan
Dermatophagoides pteronyssinus in ambient air bioaerosols.

TAN, Andrew
Angptl4 integrates dietary and microbial signals to disrupt gut barrier function in MASH.

TAN, Ern Yu
Performance of large language models for extracting clinical data from breast cancer pathology reports: a systematic review.

TAN, Andrew Tan
Nanoparticles for autoimmune diseases: advancing diagnostics and therapeutic solutions.

WONG, Sunny
Angptl4 integrates dietary and microbial signals to disrupt gut barrier function in MASH.
Comprehensive microbiome profiling reveals mucosal microbiome heterogeneity in patients with left- and right-sided colorectal neoplasia.

WUESTEFELD, Torsten 
Gut microbiota modulation of regulatory DNA elements revealed by massively parallel functional characterization.

YAO, Liang 
Ambiguous guideline recommendations harm patient care.
Should Risk of Bias Be Assessed at the Outcome Level?

YIM, Steve 
Environmental Nonessential Element Exposure and Urologic Cancer: A Systematic Review and Meta-Analysis.

YEW, Yik Weng
Dupilumab (DUPIXENT) for bullous pemphigoid.

KUSUMBE, Anjali
From repair to disease: lymphatic contributions to regeneration, cancer and ageing.

LEE, Christopher
Wireless electrostimulation implants enable sphincter neuromuscular improvement toward mixed urinary incontinence.

LEE, Jimmy
Local chemoarchitecture explains widespread lower cortical thickness associated with clinical high risk for psychosis.

PETHE, Kevin 
The Mycobacterium abscessus cytochrome bcc:aa3 oxidase structure paves the way for an agent targeting subunit QcrB.

LUO, Dahai
Cryo-EM structures of anti Z-DNA antibodies in complex with antigen reveal distinct recognition modes of a left-handed geometry.

RAMASAMY, Saravana
From repair to disease: lymphatic contributions to regeneration, cancer and ageing.

SHEN, Xiaotao
Cross-body site microbial interactions influence the human plasma metabolome.

SADARANGANI, Sapna
Immunogenicity of high-dose recombinant influenza vaccine versus standard-dose egg-grown and cell-grown vaccines among frequently and infrequently vaccinated young adults in Singapore: a randomised, controlled, double-blind, single-centre, phase 4 clinical trial.

SUNG, Joseph
Quantifying artificial sweeteners and emulsifiers in Crohn's disease and its relationship with disease activity: the ENIGMA study - a novel and targeted approach.WONG, Sunny
Cross-body site microbial interactions influence the human plasma metabolome.

YAO, Liang
Effect Modification Analyses in Individual Participant Data Meta-Analyses: A Systematic Review.

YIM, Steve
Air quality, health, and economic effects of land use and land cover changes in southeast Asia in the 21st century: a modelling study.

YOUNG, Barnaby
Immunogenicity of high-dose recombinant influenza vaccine versus standard-dose egg-grown and cell-grown vaccines among frequently and infrequently vaccinated young adults in Singapore: a randomised, controlled, double-blind, single-centre, phase 4 clinical trial.

AGRAWAL, Rupesh

Detection and quantification of fluorescein angiography leakage

Vogt-Koyanagi-Harada disease under the lens

Automated Nonperfusion Quantification in Diabetic Retinopathy

Work-up in patients with retinal vasculitis

Clinical trials in noninfectious retinal vasculitis

Management of traumatic corneal wounds

Intraocular foreign bodies in Asia

PTSD and ocular perfusion using OCT

Consensus recommendations on tear fluid terminology

CHAMBERS, John

Unexpected genotypes associated with severe paediatric conditions

CHOTIRMALL, Sanjay

Fungal-Associated Endotypes as a Treatable Trait in Bronchiectasis

AIR-NET trial design and rationale

CHUA, Karen

100 Normative Gait Profiles with 5-year fall tracking

DALAN, Rinkoo

Sirtuin 1 is an endogenous NETosis inhibitor

DUAN, Hongwei

Stable Cationic Oligoimidazoliums for Antibacterial Activity

EMERY, Jon

Time to diagnosis and treatment in lymphoma

Melanoma Self Surveillance Trial characteristics

Bowel cancer screening trial protocol

Lung cancer screening implementation trial

FOO, Jia Nee

Fibrinogen exacerbates α-synuclein aggregation

Circulatory neuro-related proteins in Parkinson’s disease

Ferroptotic cell death mechanisms in Parkinson’s disease

GOH, Wilson

A six-tiered framework for evaluating AI models

GRIVA, Konstadina

HEALing intervention for diabetic foot ulcers

Attitudinal Profiles Toward Medical Mediation

KANDIAH, Nagaendran

Association of Plasma p-tau181 and Cognition

Regional framework for ARIA detection and management

Cerebral haemodynamics and white matter hyperintensities

KUN, Liang

Protein-Capturing Microgel-Integrated Microneedle Array Patches

KUSUMBE, Anjali

Wnt-presenting materials for tissue engineering

Vascular network in bone injury repair

LEE, Jimmy

Schizophrenia: Genetics and therapeutic approaches

Structural covariance network in psychosis risk

Brain structural abnormalities in treatment-resistant schizophrenia

LEE, Bernett

Therapeutic Potential of Tulisokibart and Anti-TL1A Therapy

LIM, Jue Tao

Chikungunya transmission dynamics

Neutralizing monoclonal antibodies and post-COVID sequelae

Dengue suppression via Wolbachia mosquitoes

Sequential pneumococcal vaccination effectiveness

mRNA COVID-19 vaccination and birth defects

LIM, Su Chi

Triglyceride glucose-body roundness index and cognition

24-hour movement behaviour in type 2 diabetes

LYE, David

Current Antibiotic Options for AmpC-Producing Enterobacterales

Access to new antibacterials in Asia

LUO, Dahai

Compact conformation of DENV NS2B-NS3

Inactive Zika NS2B-NS3pro construct

MANSKI-NANKERVIS, Jo-Anne

Barriers and facilitators in FH management

Evaluating primary care EHR data for prescribing audits

NG, Adeline

NOTCH3 mutations in CADASIL

Real-world performance of plasma pTau biomarkers

NG, Olivia

AI for Single Best Answer question review

NG, Oon Tek

Antimicrobial Carbon Acid Polymer eradicates biofilms

PERUMAL, Vivek

Anatomical variations in Anatomage

PETHE, Kevin

Tuberculosis drug regimen via terminal oxidase inhibition

Gelatinase in Enterococcus faecalis infection

Phage resistance in Mycobacterium abscessus

Ceftriaxone resistance mechanisms in Neisseria

PRABHAKAR, Shyam

Spatial profiling of HER2 gastric cancer

PU, Kanyi

Serum-Inert Tandem-Locked Fluorescent Probe

RENIA, Laurent

CD44 facilitates Plasmodium invasion

Antibody responses in vector bite challenge trial

SADARANGANI, Sapna

MMRV seroprevalence in healthcare workers

SHEN, Xiaotao

Kun-peng metagenomic classification

Proteomics biomarkers for diabetic retinopathy

SUNG, Joseph

PRIMARY-AI standards for primary care

Antiplatelet resumption timing in PCI bleeding

TAN, Andrew

SERS model for lipid annotation

Angiopoietin-Like 4 therapy for lung injury

TAN, Bryan

Economic cost of knee osteoarthritis in Singapore

TAN, Emmanuel

Fibrin Glue vs Sutures in pterygium surgery

VERMA, Navin

Silver nanoparticles with antibreast cancer activity

WANG, Yulan

Quantitative lipidomic analysis using UHPLC-MS/MS

WONG, Sunny

Mutational signatures in intestinal metaplasia

Fluorescence detection of α-synuclein aggregates

YEO, Tianrong

Clinical reasoning case of rapid cognitive decline

Reflex myoclonus in stiff-person syndrome

YIM, Steve

Ozone-related health impact in Southeast Asia

Nocturnal warming and ED admissions

 

 


AGRAWAL, Rupesh

International Consensuses and Guidelines on Diagnosing and Managing Coats Disease

How Well Do Ocular Trauma Scores Predict Vision After Open Globe Injury?

Artificial Intelligence in Uveitis: A 360-Degree Perspective

CHAMBERS, John

Addressing Gaps in the Hypertension and Diabetes Care Continuum in Rural Bangladesh

CHOTIRMALL, Sanjay

Gut-lung microbial dynamics with lumacaftor/ivacaftor in children with cystic fibrosis

Clinical, molecular and microbial characterisation of the eosinophilic endotype of bronchiectasis

Lower Airway Dysbiosis in NTM+ Bronchiectasis

CHUA, Karen

Age related alteration in EEG evoked responses to balance perturbations

Vagal nerve stimulation for recovery from disorders of consciousness

CLELAND, Jennifer

Widening access to medicine: A realist review

DALAN, Rinkoo

Polyuria after spinal cord injury

Biomarkers and therapies to target endothelial dysfunction in type 2 diabetes

EJIMA, Keisuke

Integrating postal HIV testing into the HIV care cascade in Japan

EMERY, Jon

Pharmacogenetic-Guided Antidepressant Prescribing in Adolescents

FOO, Jia Nee

Association of LRRK2 p.A419V with Parkinson's Disease in East Asians

GRIVA, Konstadina

Facilitators and Barriers to Uptake of Genetic Testing in Familial Hypercholesterolemia

FH Genetic Testing in Preventive Cardiology

KANDIAH, Nagaendran

ReCOGnAIze app to detect vascular cognitive impairment

KITTO, Simon

Contextualising ventilation decisions

KONG, Keng He

Predictors of Ultrasound-Derived Muscle Thickness After Spinal Cord Injury

KONG, Li Ren

Bioenergetic diversity and nutrient auxotrophy in multiple myeloma

KUSUMBE, Anjali

The Wnt-NAD+ axis in cancer, aging, and tissue regeneration

Chronic dental lighting disrupts blood-retinal barrier homeostasis

LEE, Bernett

Persistence and spread of fluconazole-resistant Candida parapsilosis

LEOW, Melvin

Chronic curcumin versus cold stimulation for brown adipose tissue activation

Omega-3 PUFA concentrations and academic performance

LIM, Jue Tao

Neurological Events Associated With Acute Dengue Infection

Characterization of post-acute multi-organ sequelae following SARS-CoV-2 infection

Ascertaining cause-specific emergency department demand

LIM, Kah Leong

Microglial-derived Spp1 and memory decline

Single-cell transcriptomics in Parkinson's disease organoids

LYE, David

Cefiderocol versus standard therapy for bloodstream infection

Effect of vancomycin or daptomycin combination therapy on MRSA bacteraemia

MANSKI-NANKERVIS, Jo-Anne

Clinical Decision Support Tool for Early Pancreatic Cancer Detection

NGEOW, Joanne

United by Unique: reimagining future cancer care

NG, Olivia

User-centred curriculum mapping: A human-AI hybrid approach

PERUMAL, Vivek

Surgical anatomy of the anterior radiculomedullary arteries

PETHE, Kevin

Pyrazolo-Quinazoline Amines Inhibit Cytochrome bd Oxidase

PRABHAKAR, Shyam

Spatial perturb-seq: single-cell functional genomics

PU, Kanyi

Ruthenium-Based Sonoafterglow Probes

Radioisotope-mimetic molecular afterglow probe

RENIA, Laurent

Regulation of virion production by ORF8 signal peptide

RUTTER, Guy

GLP1R A316T variant functional profiling

SUBRAMANIAM, Mythily

Loneliness, social isolation and health outcomes

SUNG, Joseph

Helicobacter Pylori eradication and mortality

Bacterial genomic structural variations in autism

TAN, Andrew

Label-Free Leukocyte Biophysical Profiling

Gut-liver lipid flux checkpoint and MASLD

TAN, Bryan

Complications, Deaths, and Disability Burden Following Dengue Infection

TIEW, Pei Yee

Blood eosinophil-guided corticosteroid duration in asthma

Persistently low blood eosinophils in COPD

VERMA, Navin

Green-Synthesized Silver Nanoparticles with antibreast cancer activity

Human hepatic cell line 5: in-vitro model

WONG, Sabrina

Threshold customisation in AI X-ray triage models

YANG, Hongbin

Phenotypic effects of FBXO42 via PP4 phosphatase

YEO, Tianrong

Rituximab regimen in CNS inflammatory demyelinating diseases

Serum GFAP and NfL in multiple sclerosis progression

Outcomes during pregnancy in Asian women with MOGAD


AGRAWAL, Rupesh

Artificial intelligence in the prediction of glaucoma development and progression: A systematic review

International Consensuses and Guidelines on the Etiology, Diagnosis and Management of Intraocular Foreign Bodies (IOFBs)

ANG, Shannon

Social participation and cognitive function in Chinese older couples: Urban-rural variations in partner effects

BEST, James

The association of haptoglobin levels and phenotype with cardiovascular disease in Type 2 diabetes

CHAMBERS, John

Cardiovascular disease risk prediction in multi-ethnic Asian populations

CHANDY, George

Structural basis for the subtype-selectivity of KCa2.2 channel activators

CHEUNG, Christine

Hypertension Prevalence Among Centenarians

CHOTIRMALL, Sanjay

Multi-omics to study chronic respiratory diseases and viral infections

Reply: Methodological clarifications of AI-powered research trend analytics in bronchiectasis

Taking a wider view: The Lancet Respiratory Medicine Commission on bronchiectasis

CHUA, Karen

Deep Brain Stimulation for Disorders of Consciousness

Factors Affecting Recovery from Post-Traumatic Amnesia

Recovery from Post-Traumatic Amnesia

CLELAND, Jennifer

Beyond the faculty-student dyad

When and how to disclose AI use in academic peer review

Mixed-methods research in medical education

DALAN, Rinkoo

Evaluating the performance of a generative AI model in assessing qualitative health research

EJIMA, Keisuke

Stratification of viral shedding patterns in saliva of COVID-19 patients

EMERY, Jon

Identifying eligible patients for the Australian national lung cancer screening program

FOO, Jia Nee

Proteomic and Genetic Insights into Ancestry-Specific Associations in Parkinson's Disease

GUPTA, Dimpy

Uncovering the benefits of a multimodal intervention centered around plastinates

HO, Andy

Considerations for mHealth development

HOU, Han Wei

Real-time imaging of platelet dynamics

KANDIAH, Nagaendran

Mild Behavioral Impairment and Cortical Thinning

KITTO, Simon

Technical devices and interprofessional clinical decision-making

LEE, Bernett

The role of optical coherence tomography in the evaluation of para-chiasmal lesions

LEOW, Melvin

Real-time and digital remote nutritional assessment framework

LIM, Jue Tao

Disentangling temporal trends of clade Ib monkeypox virus transmission in Burundi

Measuring real-time disease transmissibility with temperature-dependent generation intervals

LIM, Su Chi

Urinary Branched-Chain Amino Acid Excretion and Chronic Kidney Disease Progression

LOH, Marie

Silencing of human HTT by targeted CRISPR/dCas9-mediated epigenetic editing

NG, Joanne

Leveraging Electronic Health Records to Examine Cancer Genetics Referrals

PENG, Chen

Suppressing Non-Radiative Decay via Cyanation

RAMADAN, Kristijan

Dynamins maintain nuclear envelope homeostasis and genome stability

RUTTER, Guy

Additive Effects of Dorzagliatin and GLP-1 Receptor Agonism

ER calcium stores contribute to glucose-induced Ca2+ waves

SADARANGANI, Sapna

Climate Action: ASTMH Green Task Force Survey

SUBRAMANIAM, Mythily

Public stigma towards people with mental disorders in Singapore

Mental health help-seeking behaviour among migrant workers

TAN, Andrew

The Proinflammatory Secretome of Senescent Cells

Interrupting glioblastoma malignant circuitry

WONG, Christine

Personalising the management of obesity-related asthma

Enterococcus faecalis persists and replicates intracellularly

WONG, Sunny

The role of the gut non-bacterial microbiome and its impact on obesity

WUESTEFELD, Torsten

Dual binding and efflux mechanisms regulating tumor selectivity

XIA, Yun

Toward Physiologically Relevant Organoid Models of PKD

Multilineage assembly brings spatial order to human kidney organoids

YAP, Eric

Genomic landscape of complete Acinetobacter phages