Recent Publications

Rupesh AGRAWAL

·      Optical Coherence Tomography-Based Choroidal Structural Analysis and Vascularity Index in Best Vitelliform Macular Dystrophy

·      Evaluation of Retinal Vascularity Index in Patients with COVID-19: A Case-Control Study

·      An excursion into ocular tuberculosis

Christian APFELBACHER

·      Measuring Atopic Eczema Control and Itch Intensity in Clinical Practice: A Consensus Statement From the Harmonising Outcome Measures for Eczema in Clinical Practice (HOME-CP) Initiative

George AUGUSTINE

·      Feedback inhibition underlies new computational functions of cerebellar interneurons

David BECKER

·      Challenges faced in developing an ideal chronic wound model

Olivier BEAUCHET

·      Validating the Centre of Excellence on Longevity Self-AdMinistered (CESAM) Questionnaire: An Online Self-Reported Tool for Frailty Assessment of Older Adults

Josip CAR

·      Evaluation of chatbot-delivered interventions for self-management of depression: Content analysis

·      The overlapping burden of the three leading causes of disability and death in sub-Saharan African children

·      Assessment of Clinical Information Quality in Digital Health Technologies: International eDelphi Study

·      University students' overall and domain-specific physical activity during COVID-19: A cross-sectional study in seven ASEAN countries

Lorainne Tudor CAR

·      Identifying topics for future Cochrane Public Health reviews

John CHAMBERS

·      Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis

John CHAMBERS / Marie LOH / Sanjay CHOTIRMALL / Joanne NGEOW / Yik Weng YEW / Jimmy LEE

·      Reference equations for evaluation of spirometry function tests in South Asia, and among South Asians living in other countries

Sanjay CHOTIRMALL

·      Update in COVID-19 2021

Jennifer CLELAND

·      Medical students' rural practice intention: Academic performance matters

·      Scratching beneath the surface: how organisational culture influences curricular reform

Jennifer CLELAND / Siew Ping HAN / Emmanuel TAN

·      Professional development during the COVID-19 pandemic: Crisis or opportunity?

Wilson GOH

·      Dealing with missing values in proteomics data

Konstadina GRIVA

·      A Qualitative Study of Psychosocial Factors in Patients With Knee Osteoarthritis: Insights Learned From an Asian Population

·      A qualitative systematic review of anonymous/unspecified living kidney and liver donors' perspectives

Balazs GULYAS

·      A conserved MTMR lipid phosphatase increasingly suppresses autophagy in brain neurons during aging

Han Wei HOU

·      Studying the efficacy of antiplatelet drugs on atherosclerosis by optofluidic imaging on a chip

Sarah LANGLEY

·      Evaluating the robustness of connectivity methods to noise for in silico drug repurposing studies

Bernett LEE

·      Reply

·      Distinct Transcriptomic and Metabolomic Profiles Characterize NSAID-Induced Urticaria/Angioedema Patients Undergoing Aspirin Desensitization

Eng Sing LEE

·      Defining and measuring multimorbidity in primary care in Singapore: Results of an online Delphi study

Melvin LEOW

·      Brown adipose tissue influences adiponectin and thyroid hormone changes during Graves' disease therapy

Fabian LIM

·      Editorial: Management of training frequency and intersession recovery-Molecular, cellular and physiological implications for performance and health

Jue Tao LIM

·      Assessing the efficacy of male Wolbachia-infected mosquito deployments to reduce dengue incidence in Singapore: study protocol for a cluster-randomized controlled trial

·      Perfluoroalkyl substances and lipid concentrations in the blood: A systematic review of epidemiological studies

Kah Leong LIM

·      Prostaglandin A2 Interacts with Nurr1 and Ameliorates Behavioral Deficits in Parkinson's Disease Fly Model

·      Parkin coordinates mitochondrial lipid remodeling to execute mitophagy

·      Parkin regulates neuronal lipid homeostasis through SREBP2-lipoprotein lipase pathway-implications for Parkinson's disease

·      MED13 and glycolysis are conserved modifiers of α-synuclein-associated neurodegeneration

Su Chi LIM

·      Correction: Clinical variable-based cluster analysis identifies novel subgroups with a distinct genetic signature, lipidomic pattern and cardio-renal risks in Asian patients with recent-onset type 2 diabetes

·      Urine Leucine-Rich α-2 Glycoprotein 1 (LRG1) Predicts the Risk of Progression to End-Stage Kidney Disease in Patients With Type 2 Diabetes

Wee Shiong LIM

·      Corrigendum: Effectiveness and usability of the system for assessment and intervention of frailty for community-dwelling pre-frail older adults: A pilot study

Dahai LUO

·      Molecular architecture of the Chikungunya virus replication complex

David LYE

·      Comparative neutralisation profile of SARS-CoV-2 omicron subvariants BA.2.75 and BA.5

·      Comparative effectiveness of 3 or 4 doses of mRNA and inactivated whole-virus vaccines against COVID-19 infection, hospitalization and severe outcomes among elderly in Singapore

·      Temporal Improvements in COVID-19 Outcomes for Hospitalized Adults: A Post Hoc Observational Study of Remdesivir Group Participants in the Adaptive COVID-19 Treatment Trial

Joanne NGEOW

·      Functional analysis of germline RAD51C missense variants highlight the role of RAD51C in replication fork protection

·      Case report: olaparib use in metastatic lung adenocarcinoma with BRCA2 pathogenic variant

Kanyi PU

·      Recent advances in dual- and multi-responsive nanomedicines for precision cancer therapy

·      Nanoparticles with ultrasound-induced afterglow luminescence for tumour-specific theranostics

Preman RAJALINGAM

·      Very Short Answer Questions in Team-Based Learning: Limited Effect on Peer Elaboration and Memory

Laurent RENIA

·      Integrative genetic manipulation of Plasmodium cynomolgi reveals MultiDrug Resistance-1 Y976F associated with increased in vitro susceptibility to mefloquine

·      CD8+ T-cells trigger auricular dermatitis and blepharitis in mice post-Zika virus infection in the absence of CD4+ T-cells

·      Drug interactions between common dermatological medications and the oral anti-COVID-19 agents nirmatrelvir-ritonavir and molnupiravir

Laurent RENIA / David LYE / Sapna SADARANGANI

·      Antibody response of heterologous vs homologous mRNA vaccine boosters against the SARS-CoV-2 Omicron variant: interim results from the PRIBIVAC study, A Randomized Clinical Trial

Richard REYNOLDS

·      Lymphotoxin-alpha expression in the meninges causes lymphoid tissue formation and neurodegeneration

Guy RUTTER

·      New-onset type 1 diabetes and SARS-CoV-2 infection

Maurice van STEENSEL

·      Germline intergenic duplications at Xq26.1 underlie Bazex-Dupré-Christol basal cell carcinoma susceptibility syndrome

Joseph SUNG

·      Impact of COVID-19 infection and vaccination in pancreatobiliary IgG4-related disease patients: an international multicenter study

Andrew TAN

·      Lessons on Drug Development: A Literature Review of Challenges Faced in Nonalcoholic Fatty Liver Disease (NAFLD) Clinical Trials

Hong Liang TEY

·      Notch-dependent cooperativity between myeloid lineages promotes Langerhans cell histiocytosis pathology

Navin VERMA

·      Recent Advances in Copper and Copper-Derived Materials for Antimicrobial Resistance and Infection Control

Yulan WANG

·      Acute and subchronic exposure of cyadox induced metabolic and transcriptomic disturbances in Wistar rats

Tsin Wen YEO / Andrew TAN / Sanjay CHOTIRMALL

·      The establishment of COPD organoids to study host-pathogen interaction reveals enhanced viral fitness of SARS-CoV-2 in bronchi

Yik Weng YEW

·      Facial Dermatoses Induced by Face Masks: A Systematic Review and Meta-Analysis of Observational Studies

Melvin ZHANG

·      Regular COVID-19 booster shot preference and willingness to pay in the Vietnamese population: a theory-driven discrete choice experiment

Melvin ZHANG / Ranganath VALLABHAJOSYULA

·      An Emotional Bias Modification for Children With Attention-Deficit/Hyperactivity Disorder: Co-design Study

Rupesh AGRAWAL

·      Aerobic glycolysis is important for zebrafish larval wound closure and tail regeneration

·      Uveitis Registries - A Digital Tool for Patient Care, Education, Research, and Collaboration

Yusuf ALI

·      Cell-derived nanovesicles from mesenchymal stem cells as extracellular vesicle-mimetics in wound healing

Josip CAR

·      Diabetic foot in primary and tertiary (DEFINITE) Care: A health services innovation in coordination of diabetic foot ulcer (DFU) Care within a healthcare cluster - 18-month results from an observational population health cohort study

Lorainne Tudor CAR / Helen SMITH

·      What Is the Utility of Posters? Qualitative Study of Participants at a Regional Primary Healthcare Conference in Asia

Tom CARNEY

·      Aerobic glycolysis is important for zebrafish larval wound closure and tail regeneration

John CHAMBERS

·      Network reconstruction for trans acting genetic loci using multi-omics data and prior information

John CHAMBERS / Joanne NGEOW / Eng Sing LEE

·      Analysis of clinically relevant variants from ancestrally diverse Asian genomes

Angela Chow

·      Social influence is the main driver of emergency physicians' intention to use an antibiotic clinical decision support mobile application

George CHANDY

·      Author Correction: Histone acetylome-wide associations in immune cells from individuals with active Mycobacterium tuberculosis infection

Norris Ray DUNN

·      MCC is a centrosomal protein that relocalizes to non-centrosomal apical sites during intestinal cell differentiation

Wilson GOH

·      A novel pipeline for computerized mouse spermatogenesis staging

Konstadina GRIVA

·      The role of subjective cognitive complaints in self-management among haemodialysis patients: a cross-sectional study

Siew Ping HAN / Emmanuel TAN

·      Setting the way for Instagram-based horizontal learning

Nagaendran KANDIAH

·      Call for Special Issue Papers: Stroke and Vascular Cognitive Impairment

·      Topology of diffusion changes in corpus callosum in Alzheimer's disease: An exploratory case-control study

·      Current and Future Trends in Biomarkers for the Early Detection of Alzheimer's Disease in Asia: Expert Opinion

Nien Yue KOH / Kian Bee NG

·      Freestanding and Scalable Force-softness Bimodal Sensor Arrays for Haptically Body Feature Identification

Jimmy LEE

·      Identifying psychiatric manifestations in schizophrenia and depression from audio-visual behavioural indicators through a machine-learning approach

Eng Sing LEE / David LYE / Barnaby YOUNG

·      A comparative characterization of SARS-CoV-2-specific T cells induced by mRNA or inactive virus COVID-19 vaccines

Eng Sing LEE / David LYE / Barnaby YOUNG / Laurent RENIA

·      Waning of specific antibodies against Delta and Omicron variants five months after a third dose of BNT162b2 SARS-CoV-2 vaccine in elderly individuals

Victoria LEONG

·      Learning at your brain's rhythm: individualized entrainment boosts learning for perceptual decisions

Kah Leong LIM

·      The role of tyrosine hydroxylase-dopamine pathway in Parkinson's disease pathogenesis

·      The Mood Stabilizer Lithium Slows Down Synaptic Vesicle Cycling at Glutamatergic Synapses

·      BACE2: A Promising Neuroprotective Candidate for Alzheimer's Disease

Jue Tao LIM

·      Spatial Methods for Inferring Extremes in Dengue Outbreak Risk in Singapore

·      The impact of earlier reopening to travel in the Western Pacific on SARS-CoV-2 transmission

Wee Shiong LIM

·      Lower insulin level is associated with sarcopenia in community-dwelling frail and non-frail older adults

·      Effectiveness and usability of the system for assessment and intervention of frailty for community-dwelling pre-frail older adults: A pilot study

David LYE

·      The Staphylococcus aureus Network Adaptive Platform Trial protocol: New tools for an old foe

David LYE / Barnaby YOUNG / Laurent RENIA

·      Conserved longitudinal alterations of anti-S-protein IgG subclasses in disease progression in initial ancestral Wuhan and vaccine breakthrough Delta infections

Reddy MOGALI / Preman RAJALINGAM

·      Investigating the effectiveness of three-dimensionally printed anatomical models compared with plastinated human specimens in learning cardiac and neck anatomy: A randomized crossover study

Oon Tek NG

·      Factors associated with high alanine aminotransferase (ALT) and cirrhosis in people living with HIV on combination antiretroviral treatment (cART) in the Asia-Pacific

Joanne NGEOW

·      General practitioners' (GPs) experience, attitudes and needs on clinical genetic services: a systematic review

Kanyi PU

·      A Dual-Locked Tandem Fluorescent Probe for Imaging of Pyroptosis in Cancer Chemo-immunotherapy

·      Checkpoint Nano-PROTACs for Activatable Cancer Photo-immunotherapy

Laurent RENIA

·      Autoantibodies against type I IFNs in patients with critical influenza pneumonia

Richard REYNOLDS

·      Diverse pathways to neuronal necroptosis in Alzheimer's disease

Guy RUTTER

·      In vivo and in vitro characterization of GL0034, a novel long-acting glucagon-like peptide-1 receptor agonist

Helen SMITH

·      Caring for Carers (C4C): Results from a feasibility randomised controlled trial of positive written disclosure for older adult carers of people with psychosis

·      Improving prescribing: a feasibility study of pharmacogenetic testing with clinical decision support in primary healthcare in Singapore

Maurice van STEENSEL

·      Combined germline pathogenic variants in FLCN and TP53 are associated with early onset renal cell carcinoma and brain tumors

Joseph SUNG

·      Squalene epoxidase drives cancer cell proliferation and promotes gut dysbiosis to accelerate colorectal carcinogenesis

Joseph SUNG / Sunny Wong

·      Third Asia-Pacific consensus recommendations on colorectal cancer screening and postpolypectomy surveillance

Andrew TAN

·      Utility of Human Relevant Preclinical Animal Models in Navigating NAFLD to MAFLD Paradigm

Cher Heng TAN

·      Efficacy of texture analysis of pre-operative magnetic resonance imaging in predicting microvascular invasion in hepatocellular carcinoma

Hong Liang TEY

·      Effectiveness of a Fourth Dose of COVID-19 mRNA Vaccine Against Omicron Variant Among Elderly People in Singapore

·      SARS-CoV-2 Omicron variant emerged under immune selection

Hong Liang TEY / Angela CHOW

·      Intranasal octenidine for methicillin-resistant Staphylococcus aureus (MRSA) carriers and universal octenidine bathing reduced MRSA acquisition in an acute-care general ward

Walter WAHLI

·      Knocking on GDF15's door for the treatment of type 2 diabetes mellitus

Sunny WONG

·      Oral exposure to Ag or TiO2 nanoparticles perturbed gut transcriptome and microbiota in a mouse model of ulcerative colitis

Yun XIA

·      How does diabetes cause susceptibility to COVID-19 in the kidney: new clues provided by organoids

Eric YAP

·      Single Escherichia coli bacteria detection using a chemiluminescence digital microwell array chip

Tsin Wen YEO

·      Association of Neutrophil Mediators With Dengue Disease Severity and Cardiac Impairment in Adults

Tsin Wen YEO / Angela CHOW / Sapna SADARANGNI / Barnaby YOUNG / Rinkoo DALAN

·      DYNAMIC cohort study evaluating metabolic predictors of influenza vaccine immune response in older adults

Melvyn ZHANG

·      Social Media Addiction among Vietnam Youths: Patterns and Correlated Factors

·      Prevalence of depression and its potential contributing factors in patients with enterostomy: A meta-analytical review

Rupesh AGRAWAL

·      Anti-tubercular therapy in the treatment of tubercular uveitis: A systematic review and meta-analysis

·      Central retinal vein occlusion post ChAdOx1 nCoV-19 vaccination - can it be explained by the two-hit hypothesis?

·      Endogenous Endophthalmitis - A Major Review

·      Nonsurgical Management of Severe Viral Keratitis with Hypopyon and Retrocorneal Plaques: A Case Series

Christian APFELBACHER

·      Measuring Atopic Eczema Control and Itch Intensity in Clinical Practice: A Consensus Statement From the Harmonising Outcome Measures for Eczema in Clinical Practice (HOME-CP) Initiative

Bernhard BOEHM

·      SPINA Carb: a simple mathematical model supporting fast in-vivo estimation of insulin sensitivity and beta cell function

·      Whole-genome sequencing of multiple related individuals with type 2 diabetes reveals an atypical likely pathogenic mutation in the PAX6 gene

Josip CAR

·      Effects of fun-seeking and external locus of control on smoking behaviour: a cross-sectional analysis on a cohort of working men in Singapore

·      Mapping development and health effects of cooking with solid fuels in low-income and middle-income countries, 2000-18: a geospatial modelling study

·      The clusters of health-risk behaviours and mental wellbeing and their sociodemographic correlates: a study of 15,366 ASEAN university students

Lorainne CAR

·      Designing, Developing, Evaluating, and Implementing a Smartphone-Delivered, Rule-Based Conversational Agent (DISCOVER): Development of a Conceptual Framework

·      Conversational Agents in Health Care: Scoping Review of Their Behavior Change Techniques and Underpinning Theory

·      Sources of information on diabetes and its demographic correlates: a nationwide survey among Singapore residents

·      Public perceptions of a healthy lifestyle change conversational agent in Singapore: A qualitative study

John CHAMBERS

·      A saturated map of common genetic variants associated with human height

Christine CHEUNG

·      Single-Cell Transcriptome of Wet AMD Patient-Derived Endothelial Cells in Angiogenic Sprouting

Jennifer CLELAND

·      CARDA: Guiding document analyses in health professions education research

·      "It's making me think outside the box at times": a qualitative study of dynamic capabilities in surgical training

·      What is the evidence for biology as the 'heart of eligibility' to study medicine? A retrospective analysis

Norris Ray DUNN

·      MCC is a centrosomal protein that relocalizes to non-centrosomal apical sites during intestinal cell differentiation

Wilson GOH

·      A novel pipeline for computerized mouse spermatogenesis staging

Konstadina GRIVA / Lorainne CAR

·      Subjective cognitive complaints in end-stage renal disease: a systematic review and meta-analysis

Eng Sing LEE / David LYE / Barnaby YOUNG

·      A comparative characterization of SARS-CoV-2-specific T cells induced by mRNA or inactive virus COVID-19 vaccines

Jimmy LEE

·      DNA methylation levels of RELN promoter region in ultra-high risk, first episode and chronic schizophrenia cohorts of schizophrenia

Melvin LEOW

·      Gender differences in fasting and postprandial metabolic traits predictive of subclinical atherosclerosis in an asymptomatic Chinese population

Kah Leong LIM

·      Intestine-derived α-synuclein initiates and aggravates pathogenesis of Parkinson's disease in Drosophila

·      Parkin coordinates mitochondrial lipid remodeling to execute mitophagy

Allen LIU 

·      Handheld ultrasound-guided cannulation of difficult hemodialysis arteriovenous access: A randomized controlled trial

David LYE

·      SARS-CoV-2 Omicron variant emerged under immune selection

David LYE / Barnaby YOUNG / Laurent RENIA

·      Efficient recall of SARS-CoV-2 variant-reactive B cells and T responses in the elderly upon heterologous mRNA vaccines as boosters

Oon Tek NG / Barnaby YOUNG

·      Residual humoral immunity sustained over decades in a cohort of vaccinia-vaccinated individuals

Joanne NGEOW

·      Colorectal cancer incidences in Lynch syndrome: a comparison of results from the prospective lynch syndrome database and the international mismatch repair consortium

Kanyi PU

·      Activating Nanomedicines with Electromagnetic Energy for Deep-Tissue Induction of Immunogenic Cell Death in Cancer Immunotherapy

Laurent RENIA

·      Evolving perspectives on rosetting in malaria

·      Decoding the Human Genetic and Immunological Basis of COVID-19 mRNA Vaccine-Induced Myocarditis

Richard REYNOLDS

·      "Ependymal-in" Gradient of Thalamic Damage in Progressive Multiple Sclerosis

Maurice van STEENSEL

·      Aberrant Wnt Signaling Induces Comedo-Like Changes in The Murine Upper Hair Follicle

Joseph SUNG

·      Endoscope-assisted magnetic helical micromachine delivery for biofilm eradication in tympanostomy tube

Joseph SUNG / Sunny WONG

·      Altered Mycobiota Signatures and Enriched Pathogenic Aspergillus rambellii Are Associated With Colorectal Cancer Based on Multicohort Fecal Metagenomic Analyses

Joseph SUNG / Sunny WONG / Andrew TAN / Sanjay CHOTIRMALL

·      Microbial Dysregulation of the Gut-Lung Axis in Bronchiectasis

Tianrong YEO

·      Metabolomics detects clinically silent neuroinflammatory lesions earlier than neurofilament-light chain in a focal multiple sclerosis animal model

Tsin Wen YEO

·      Clinical and prognostic relevance of sST2 in adults with dengue-associated cardiac impairment and severe dengue

·      The Association of Baseline Plasma SARS-CoV-2 Nucleocapsid Antigen Level and Outcomes in Patients Hospitalized With COVID-19

Yik Weng YEW

·      Hand hygiene and hand eczema: a systematic review and meta-analysis

Rupesh AGRAWAL 

·      Global Current Practice Patterns for the Management of Hyphema

·      OCULAR MANIFESTATIONS IN IGA NEPHROPATHY

·      Ocular Toxoplasmosis

·      Optical Coherence Tomography-Based Choroidal Structural Analysis and Vascularity Index in Best Vitelliform Macular Dystrophy

Bernhard BOEHM

·      Adult-onset autoimmune diabetes

Stefan BORNSTEIN

·      Gasdermin D-deficient mice are hypersensitive to acute kidney injury

Josip CAR

·      Assessment of inter-rater agreement of the American Society of Anesthesiologists physical status classification system in a women's tertiary hospital: An observational study

·      Evaluation of chatbot-delivered interventions for self-management of depression: Content analysis

Lorainne CAR

·      The use of Telegram in surgical education: An exploratory study

Lorainne CAR / Helen SMITH

·      Recruitment of general practitioners in China: a scoping review of strategies and challenges

Tom CARNEY

·      Aerobic glycolysis is important for zebrafish larval wound closure and tail regeneration

John CHAMBERS

·      The iHealth-T2D study: a cluster randomised trial for the prevention of type 2 diabetes amongst South Asians with central obesity and prediabetes-a statistical analysis plan

George CHANDY

·      Author Correction: Histone acetylome-wide associations in immune cells from individuals with active Mycobacterium tuberculosis infection

Jennifer CLELAND

·      BMAT's predictive validity for medical school performance: a retrospective cohort study

·      Burn-out and relationship with the learning environment among psychiatry residents: a longitudinal study

Peng CHEN

·      Colorimetric microneedle patches for multiplexed transdermal detection of metabolites

Sanjay CHOTIRMALL

·      Therapeutic Targeting of the Respiratory Microbiome.

Angela CHOW

·      "Antibiotics are for everyone, our past and our future generations, right? If antibiotics are dead, we will be in big trouble": Building on community values for public engagement on appropriate use of antibiotics in Singapore

Rinkoo DALAN

·      Reactive Oxygen Species Scavenging Nanomedicine for The Treatment of Ischemic Heart Disease

Wilson GOH

·      Are batch effects still relevant in the age of big data?

Balazs GULYAS

·      The Utilization of Physiologically Active Molecular Components of Grape Seeds and Grape Marc

Nagaendran KANDIAH

·      Amyloid-Tau-Neurodegeneration Profiles and Longitudinal Cognition in Sporadic Young-Onset F3299Dementia

·      Stage-dependent differential influence of metabolic and structural networks on memory acroF3299ss Alzheimer's disease continuum

Nien Yue KOH / Kian Bee NG

·      Freestanding and Scalable Force-softness Bimodal Sensor Arrays for Haptically Body Feature Identification

Sarah LANGLEY

·      Ermin deficiency leads to compromised myelin, inflammatory milieu, and susceptibility to demyelinating insult

Bernett LEE

·      Infiltration and local differentiation of bone marrow-derived integrinβ7-positive mast cell progenitors in atopic dermatitis-like skin

Eng Sing LEE

·      Asian perspectives on NAPCRG

Melvin LEOW

·      Editorial: Thyroid hormones and cardiac arrhythmia

Kah Leong LIM

·      Customized strategies for high-yield purification of retinal pigment epithelial cells differentiated from different stem cell sources

Su Chi LIM

·      Comment on Colclough et al. and Saint-Martin et al. Syndromic Monogenic Diabetes Genes Should Be Tested in Patients With a Clinical Suspicion of Maturity-Onset Diabetes of the Young. Diabetes 2022;71:530-537, and Gene Panel Sequencing of Patients With Monogenic Diabetes Brings to Light Genes Typically Associated With Syndromic Presentations. Diabetes 2022;71:578-584

·      Correction: Clinical variable-based cluster analysis identifies novel subgroups with a distinct genetic signature, lipidomic pattern and cardio-renal risks in Asian patients with recent-onset type 2 diabetes

·      Decline in skeletal muscle mass is associated with cognitive decline in type 2 diabetes mellitus

Wee Shiong LIM

·      Functional mobility decline and incident mild cognitive impairment and early dementia in community-dwelling older adults: the Singapore Longitudinal Ageing Study

David LYE

·      Effectiveness of primary series and booster vaccination against SARS-CoV-2 infection and hospitalisation among adolescents aged 12-17 years in Singapore: a national cohort study

·      Effectiveness of a Fourth Dose of COVID-19 mRNA Vaccine Against Omicron Variant Among Elderly People in Singapore

·      First-in-Human Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a Rapidly Developed SARS-CoV-2 Therapeutic Antibody, AOD01, in Healthy Adults

Preman RAJALINGAM / Reddy MOGALI

·      Students' learning experiences of three-dimensional printed models and plastinated specimens: a qualitative analysis

Laurent RENIA

·      Editorial: Models to study malaria parasite-host interactions and pathogenesis

·      Molecular Characterization of MHC Class I Alpha 1 and 2 Domains in Asian Seabass ( Lates calcarifer)

Laurent RENIA / David LYE

·      Monkeypox: disease epidemiology, host immunity and clinical interventions

Laurent RENIA / David LYE / Barnaby YOUNG

·      In vitro vaccine challenge of PBMCs from BNT162b2 anaphylaxis patients reveals HSP90α-NOD2-NLRP3 nexus

Guy RUTTER

·      Human alpha cell transcriptomic signatures of types 1 and 2 diabetes highlight disease-specific dysfunction pathways

·      Vertical sleeve gastrectomy normalizes circulating glucocorticoid levels and lowers glucocorticoid action tissue-selectively in mice

Edwin SEET

·      Characteristics of Patients with Unrecognized Sleep Apnea Requiring Postoperative Oxygen Therapy

Joseph SUNG

·      Fibrotic immune microenvironment remodelling mediates superior anti-tumor efficacy of a nano-PD-L1 trap in hepatocellular carcinoma

·      High Sensitivity of Shotgun Metagenomic Sequencing in Colon Tissue Biopsy by Host DNA Depletion

·      Randomized Clinical Trials of Machine Learning Interventions in Health Care: A Systematic Review

Andrew TAN

·      Squid Suckerin-spider Silk Fusion Protein Hydrogel for Delivery of Mesenchymal Stem Cell Secretome to Chronic Wounds

Andrew TAN / Sanjay CHOTIRMALL

·      Neisseria species as pathobionts in bronchiectasis

Ern Yu TAN

·      Relevance of the MHC region for breast cancer susceptibility in Asians

Walter WAHLI

·      Knocking on GDF15's door for the treatment of type 2 diabetes mellitus.

Sunny WONG

·      Antibody stabilization for thermally accelerated deep immunostaining

·      Oral exposure to Ag or TiO 2 nanoparticles perturbed gut transcriptome and microbiota in a mouse model of ulcerative colitis

Eric YAP

·      Draft Genome Sequence of Multidrug Resistant Klebsiella pneumoniae Strain C43 Isolated from Environmental Water Sample

·      Effects of age, sex, serostatus, and underlying comorbidities on humoral response post-SARS-CoV-2 Pfizer-BioNTech mRNA vaccination: a systematic review

Tsin Wen YEO

·      A double whammy: The association between comorbidities and severe dengue among adult patients-A matched case-control study

·      Association of Neutrophil Mediators With Dengue Disease Severity and Cardiac Impairment in Adults

·      Efficacy and Safety of Ensovibep for Adults Hospitalized With COVID-19 : A Randomized Controlled Trial

Steve YIM

·      Analysis of the air quality in upper atmospheric boundary layer in a high-density city in Asia using 3-year vertical profiles measured by the 3-Dimensional Real-Time Atmospheric Monitoring System (3DREAMS)

Barnaby YOUNG

·      Rapid Evaluation of Vaccine Booster Effectiveness against SARS-CoV-2 Variants

Rupesh AGRAWAL

·      Globe and Adnexal Trauma Terminology Survey

Yusuf ALI

·      Ceramide Acyl Chain Length and Its Relevance to Intracellular Lipid Regulation

·      Perception and reaction of Nanyang Technological University (NTU) researchers to different forms of research integrity education modality

Wei Tech ANG

·      Current clinical practice in managing somatosensory impairments and the use of technology in stroke rehabilitation

George AUGUSTINE

·      Alzheimer's Disease: Effects on brain circuits and synapses

Olivier BEAUCHET

·      CARE frailty e-health scale: Association with incident adverse health outcomes and comparison with the Cardiovascular Health Study frailty scale in the NuAge cohort

·      The prevention of major neurocognitive disorders in the next phase of COVID-19 pandemic: On being proactive

·      Validating the Centre of Excellence on Longevity Self-AdMinistered (CESAM) Questionnaire: An Online Self-Reported Tool for Frailty Assessment of Older Adults

Tom CARNEY

·      Slit-Robo signalling establishes a Sphingosine-1-phosphate gradient to polarise fin mesenchyme

John CHAMBERS

·      A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids

·      Characteristics and Outcomes of Community Health Worker Training to Improve the Prevention and Control of Cardiometabolic Diseases in Low and Middle-Income Countries: A Systematic Review

·      GWAS meta-analysis of intrahepatic cholestasis of pregnancy implicates multiple hepatic genes and regulatory elements

Sanjay CHOTIRMALL

·      Microbiomics-focused Data Integration: A Fresh Solve for the Rubik's Cube of Endophenotyping?

·      Sensitisation to recombinant Aspergillus fumigatus allergens and clinical outcomes in COPD

Angela CHOW

·      Social influence is the main driver of emergency physicians' intention to use an antibiotic clinical decision support mobile application

Karen CHUA

·      Long-Term Outcomes of Patients with Primary Brain Tumors after Acute Rehabilitation: A Retrospective Analyses of Factors

·      The Impact of Stroke Subtype on Recovery and Functional Outcome after Inpatient Rehabilitation: A Retrospective Analysis of Factors

Jennifer CLELAND

·      Disruption in the space-time continuum: why digital ethnography matters

·      Medical students' rural practice intention: Academic performance matters

Rinkoo DALAN

·      Cardiorespiratory fitness and fat oxidation during exercise in Chinese, Indian, and Malay men with elevated body mass index

Jia Nee FOO

·      Biallelic variants in CHST3 cause Spondyloepiphyseal dysplasia with joint dislocations in three Pakistani kindreds

Wilson GOH

·      Perspectives for better batch effect correction in mass-spectrometry-based proteomics

Wilson GOH / Michael STANLEY-BAKER

·      Data considerations for predictive modeling applied to the discovery of bioactive natural products

Balazs GULYAS

·      Biomedical and Textile Applications of Alternanthera sessilis Leaf Extract Mediated Synthesis of Colloidal Silver Nanoparticle

Siew Ping HAN / Emmanuel TAN

·      Setting the way for Instagram-based horizontal learning

Philip INGHAM

·      A transgenic zebrafish for in vivo visualization of cilia

Suresh JESUTHASAN

·      Dynamics and potential significance of spontaneous activity in the habenula

Nagaendran KANDIAH 

·      Correlation Between Plasma Oligomeric Amyloid-β and Performance on the Language Neutral Visual Cognitive Assessment Test in a Southeast Asian Population

·      Upregulated Blood miR-150-5p in Alzheimer's Disease Dementia Is Associated with Cognition, Cerebrospinal Fluid Amyloid-β, and Cerebral Atrophy

Sarah LANGLEY

·      A high-resolution map of human RNA translation

Bernett LEE

·      Analysis of archaic human haplotypes suggests that 5hmC acts as an epigenetic guide for NCO recombination

·      Distinct Transcriptomic and Metabolomic Profiles Characterize NSAID-Induced Urticaria/Angioedema Patients Undergoing Aspirin Desensitization

Eng Sing LEE / David LYE / Laurent RENIA

·      Heterologous booster vaccination with CoronaVac following prime vaccination with mRNA vaccine

Jimmy LEE

·      Metabolic syndrome and cardiovascular risk between clozapine and non-clozapine antipsychotic users with schizophrenia

Melvin LEOW

·      Minor perturbations of thyroid homeostasis and major cardiovascular endpoints-Physiological mechanisms and clinical evidence

Kah Leong LIM

·      Blood-brain barrier (BBB)-on-a-chip: a promising breakthrough in brain disease research

Wee Shiong LIM

·      One-Carbon Metabolism Biomarkers and Risks of Incident Neurocognitive Disorder among Cognitively Normal Older Adults

Dahai Luo

·      Crystal structure of the Rubella virus protease reveals a unique papain-like protease fold

·      ZAP isoforms regulate unfolded protein response and epithelial- mesenchymal transition

David LYE

·      IDentif.AI-Omicron: Harnessing an AI-Derived and Disease-Agnostic Platform to Pinpoint Combinatorial Therapies for Clinically Actionable Anti-SARS-CoV-2 Intervention 

·      Comparative neutralisation profile of SARS-CoV-2 omicron subvariants BA.2.75 and BA.5

·      Vaccine effectiveness against Delta, Omicron BA.1 and BA.2 in a highly vaccinated Asian setting: a test-negative design study

Oon Tek NG

·      Analysis of COVID-19 Incidence and Severity Among Adults Vaccinated With 2-Dose mRNA COVID-19 or Inactivated SARS-CoV-2 Vaccines With and Without Boosters in Singapore 

·      Impact of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccination and Pediatric Age on Delta Variant Household Transmission

·      Prevalence and Distribution of mcr Genotypes in a Large Retrospective Collection of Clinical Carbapenemase-Producing Enterobacterales, Singapore

Kevin PETHE

·      Pharmacological perturbation of thiamine metabolism sensitizes Pseudomonas aeruginosa to multiple antibacterial agents

Laurent RENIA

·      Improving in vitro continuous cultivation of Plasmodium cynomolgi, a model for P. vivax

Laurent RENIA / David LYE

·      Lower vaccine-acquired immunity in the elderly population following two-dose BNT162b2 vaccination is alleviated by a third vaccine dose

·      Recessive inborn errors of type I IFN immunity in children with COVID-19 pneumonia

Jerome ROTGANS / Preman RAJALINGAM / Reddy MOGALI

·      A Validated Instrument Measuring Students' Perceptions on Plastinated and Three-Dimensional Printed Anatomy Tools

Guy RUTTER

·      Vertical Sleeve Gastrectomy Lowers SGLT2/Slc5a2 Expression in the Mouse Kidney

Helen SMITH

·      Lay perceptions of diabetes mellitus and prevention costs and benefits among adults undiagnosed with the condition in Singapore: a qualitative study

Maurice van STEENSEL

·      Germline intergenic duplications at Xq26.1 underlie Bazex-Dupré-Christol basal cell carcinoma susceptibility syndrome

Mythily SUBRAMANIAM

·      Factor structure of the diabetes knowledge questionnaire and the assessment of the knowledge of risk factors, causes, complications, and management of diabetes mellitus: A national population-based study in Singapore

Joseph SUNG

·      Randomized controlled trials of artificial intelligence in clinical practice: A systematic review

Joseph SUNG / Sunny WONG

·      Third Asia-Pacific consensus recommendations on colorectal cancer screening and postpolypectomy surveillance

·      Timing of endoscopy for acute upper gastrointestinal bleeding: a territory-wide cohort study

Cher Heng TAN

·      Variant Hepatocellular Carcinoma Subtypes According to the 2019 WHO Classification: An Imaging-Focused Review

Ern Yu TAN

·      Impact of cytochrome P450 2D6 polymorphisms on decision-making and clinical outcomes in adjuvant hormonal therapy for breast cancer

·      Mammography screening is associated with more favourable breast cancer tumour characteristics and better overall survival: case-only analysis of 3739 Asian breast cancer patients

Hong Liang TEY

·      Amicrobial pustulosis of the folds with peculiar palmoplantar involvement

Navin VERMA

·      Nanobiotics against antimicrobial resistance: harnessing the power of nanoscale materials and technologies

Navin VERMA / George CHANDY

·      Obstacles for T-lymphocytes in the tumour microenvironment: Therapeutic challenges, advances and opportunities beyond immune checkpoint

Yulan WANG

·      Heme cross-feeding can augment Staphylococcus aureus and Enterococcus faecalis dual species biofilms

·      Loss of FOCAD, operating via the SKI messenger RNA surveillance pathway, causes a pediatric syndrome with liver cirrhosis

Yun XIA

·      How does diabetes cause susceptibility to COVID-19 in the kidney: new clues provided by organoids

Yik Weng YEW

·      Facial Dermatoses Induced by Face Masks: A Systematic Review and Meta-Analysis of Observational Studies

Steve YIM

·      Long-term trends of atmospheric hot-and-polluted episodes (HPE) and the public health implications in the Pearl River Delta region of China

Rupesh AGRAWAL

• Clinical characteristics and treatment outcomes of Cytomegalovirus anterior uveitis and endotheliitis: a systematic review and meta-analysis
• Longitudinal analysis of the retina and choroid in cognitively normal individuals at higher genetic risk for Alzheimer disease
• MULTICOLOR CONFOCAL SCANNING LASER OPHTHALMOSCOPE IMAGING IN POSTERIOR UVEITIS

  Yusuf ALI / Guy RUTTER

• Mitofusins Mfn1 and Mfn2 are Required to Preserve Glucose- But Not Incretin-Stimulated Beta Cell Connectivity and Insulin Secretion

  Christian APFELBACHER

• Quality of life in atopic dermatitis in Asian countries: a systematic review

  Olivier BEAUCHET

• Improving the mental and physical health of older community-dwellers with a museum participatory art-based activity: results of a multicentre randomized controlled trial
• Emergency Room Evaluation and Recommendations and Risk Screening of Incident Major Neurocognitive Disorders in Older Females: Results of an Observational Population-Based Cohort Study
• Using Interaction between Cognitive and Motor Impairment for Risk Screening of Major Neurocognitive Disorders: Results of the EPIDOS Observational Cohort Study

  David BECKER / Sing Yian CHEW

• Bio-Mimicking Acellular Wet Electrospun Scaffolds Promote Accelerated Integration and Re-Epithelialization of Full-Thickness Dermal Wounds

  Josip CAR

• Prevalence of Health-Risk Behaviors and Mental Well-Being of ASEAN University Students in COVID-19 Pandemic

  Lorainne Tudor CAR

• Estimates, trends, and drivers of the global burden of type 2 diabetes attributable to PM 2·5 air pollution, 1990-2019: an analysis of data from the Global Burden of Disease Study 2019

  John Chambers / Marie LOH / Sanjay CHOTIRMALL / Joanne NGEOW / Yik Weng YEW / Jimmy LEE

• Reference equations for evaluation of spirometry function tests in South Asia, and amongst South Asians living in other countries

  Christine CHEUNG

• Generating human artery and vein cells from pluripotent stem cells highlights the arterial tropism of Nipah and Hendra viruses
• Hypercoagulability, endotheliopathy, and inflammation approximating 1 year after recovery: Assessing the long-term outcomes in COVID-19 patients

  Angela CHOW

• The value of social interactions and incentives on the use of a digital contact tracing tool post COVID-19 lockdown in Singapore

  Jennifer CLELAND

• Differential attainment at MRCS according to gender, ethnicity, age and socioeconomic. factors: a retrospective cohort study
• Exploring variation in surgical practice: does surgeon personality influence anastomotic decision-making?
• Performance at medical school selection correlates with success in Part A of the intercollegiate Membership of the Royal College of Surgeons (MRCS) examination

  Rinkoo DALAN / Stefan BORNSTEIN / Bernhard BOEHM

• Cushing's Disease Management: Glimpse Into 2051

  Wilson GOH

• Resolving missing protein problems using functional class scoring
• Doppelgänger spotting in biomedical gene expression data

  Konstadina GRIVA

• Protocol for a randomised controlled trial on impact of comprehensive geriatric and supportive assessment versus standard care in older adults with cancer undergoing curative treatment: The Geriatric Oncology SuPportive clinic for ELderly (GOSPEL) study
• Determining the Prevalence and Correlates of COVID-19 Booster Vaccine Hesitancy in the Singapore Population Following the Completion of the Primary Vaccination Series

  Konstadina GRIVA / Lorainne CAR

• Information needs and sources of information among people with depression and anxiety: a scoping review

  Balazs GULYAS

• Differential effects of white matter hyperintensities and regional amyloid deposition on regional cortical thickness
• Steady-state responses to concurrent melodies: source distribution, top-down, and bottom-up attention
• Synthesis and preclinical application of a Prussian blue-based dual fluorescent and magnetic contrast agent (CA)

  Nagaendran KANDIAH

• Alzheimer's Disease Blood Biomarkers Associated With Neuroinflammation as Therapeutic Targets for Early Personalized Intervention

  Sarah LANGLEY

• Molecular Subgroups of Intrahepatic Cholangiocarcinoma Discovered by Single-Cell RNA Sequencing-Assisted Multiomics Analysis

  Andy HO / Jimmy LEE

• Living Losses in Stroke Caregiving: A Qualitative Systematic Review of Systematic Reviews on Psycho-Socio-Emotional Challenges and Coping Mechanisms

  Jimmy LEE

• Neuroanatomical heterogeneity and homogeneity in individuals at clinical high risk for psychosis

  Dahai LUO

• Molecular basis of specific viral RNA recognition and 5'-end capping by the Chikungunya virus nsP1

  David LYE

• Early oral stepdown antibiotic therapy versus continuing intravenous therapy for uncomplicated Gram-negative bacteraemia (the INVEST trial): study protocol for a multicentre, randomised controlled, open-label, phase III, non-inferiority trial
• Effectiveness of BNT162b2 Vaccine against Omicron in Children 5 to 11 Years of Age

  Joanne NGEOW

• Automatic DNA replication tract measurement to assess replication and repair dynamics at the single molecule level

  Michael NILSSON

• Correction: Assessing the Efficacy of an Individualized Psychological Flexibility Skills Training Intervention App for Medical Student Burnout and Well-being: Protocol for a Randomized Controlled Trial

  Kanyi PU

• Activatable cancer sono-immunotherapy using semiconducting polymer nanobodies
• An Activatable Polymeric Nanoprobe for Fluorescence and Photoacoustic Imaging of Tumor-Associated Neutrophils in Cancer Immunotherapy
• Chemiluminescent Probes with Long-Lasting High Brightness for In Vivo Imaging of Neutrophils

  Laurent RENIA

• Respiratory viral infections in otherwise healthy humans with inherited IRF7 deficiency

  Richard REYNOLDS

• Lymphotoxin-alpha expression in the meninges causes lymphoid tissue formation and neurodegeneration

  Guy RUTTER

• Glucose-Dependent miR-125b is a Negative Regulator of β-Cell Function

  Sapna SADARANGANI

• Why Climate Action Is Global Health Action

  Helen SMITH

• General practitioners' views on retaining Singapore's primary care doctors: a cross-sectional survey and qualitative analysis
• Perceived Stress and Interest in Non-Invasive Aesthetic Procedures During the COVID-19 Pandemic

  Joseph SUNG

• Aberrant cholesterol metabolic signaling impairs antitumor immunosurveillance through natural killer T cell dysfunction in obese liver
• The use of topical mineral powder as monotherapy for treatment of active peptic ulcer bleeding

  Boon Huan TAN

• The Cellular Characterization of SARS-CoV-2 Spike Protein in Virus-Infected Cells Using the Receptor Binding Domain Binding Specific Human Monoclonal Antibodies

  Cher Heng TAN

• Gadoxetate-Enhanced MRI as a Diagnostic Tool in the Management of Hepatocellular Carcinoma: Report from a 2020 Asia-Pacific Multidisciplinary Expert Meeting
• Algorithm-based approach to focal liver lesions in contrast-enhanced ultrasound

  Hong Liang TEY

• A 3D-printed transepidermal microprojection array for human skin microbiome sampling

  Hong Liang TEY / Andrew TAN

• Scar prevention through topical delivery of gelatin-tyramine-siSPARC nanoplex loaded in dissolvable hyaluronic acid microneedle patch across skin barrier

  Walter Wahli

• Peroxisomal Proliferator-Activated Receptor β/ δ Deficiency Induces Cognitive Alterations

  Sunny WONG / Joseph SUNG

• Artificial intelligence-assisted colonoscopy for colorectal cancer screening: a multicenter randomized controlled trial
• Meta-analysis of mucosal microbiota reveals universal microbial signatures and dysbiosis in gastric carcinogenesis

  Franklin ZHONG

• Human NLRP1 is a sensor of pathogenic coronavirus 3CL proteases in lung epithelial cells

Rupesh AGRAWAL

·      Intermediate Uveitis: A Review

·      The Collaborative Ocular Tuberculosis Study (COTS) calculator-a consensus-based decision tool for initiating antitubercular therapy in ocular tuberculosis

Yusuf ALI / Sunny WONG

·      Stress Hyperglycemia Is Associated With an Increased Risk of Subsequent Development of Diabetes Among Bacteremic and Nonbacteremic Patients

Christian APFELBACHER

·      The HOME Core outcome set for clinical trials of atopic dermatitis

George AUGUSTINE

·      Topologically Organized Networks in the Claustrum Reflect Functional Modularization

Per-Olof BERGGREN

·      Intravital Ca 2+ imaging of pancreatic β cell function after bariatric surgery

Stefan BORNSTEIN

·      An update on adrenocortical cell lines of human origin

Josip CAR

·      Developing integration among stakeholders in the primary care networks of Singapore: a qualitative study

John CHAMBERS

·      Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals

George CHANDY

·      Mechanisms Underlying C-type Inactivation in Kv Channels: Lessons From Structures of Human Kv1.3 and Fly Shaker-IR Channels

Sanjay CHOTIRMALL

·      Association of nanoparticle exposure with serum metabolic disorders of healthy adults in printing centers

Angela CHOW

·      Health Information Orientation Profiles and Their Association with Knowledge of Antibiotic Use in a Population with Good Internet Access: A Cross-Sectional Study

·      Sociodemographic and clinical factors, visit expectations and driving factors for emergency department attendance for uncomplicated upper respiratory tract infection

Angela CHOW / Oon Tek NG

·      Whole genome sequencing reveals hidden transmission of carbapenemase-producing Enterobacterales

Jennifer CLELAND

·      Scotland's "Incentivised Laparoscopy Practice" programme: Engaging trainees with take-home laparoscopy simulation

Rinkoo DALAN / Bernhard BOEHM

·      Reply - Letter to the editor: "Micronutrient supplementation, COVID-19 vaccination and adverse effect"

Jia Nee FOO

·      Gene-Environment Interactions in Face Categorization: Oxytocin Receptor Genotype x Childcare Experience Shortens Reaction Time

Balazs GULYAS

·      A Brief Introduction to Magnetoencephalography (MEG) and Its Clinical Applications

·      The Galenic Heart in the Gothic Cathedral and the Adjournment in Discovery of Circulation

Balazs GULYAS / Annabel CHEN

·      Stronger brain activation for own baby but similar activation toward babies of own and different ethnicities in parents living in a multicultural environment

Jimmy LEE

·      Haptoglobin in ultra-high risk of psychosis - Findings from the longitudinal you th at risk study (LYRIKS)

Kah Leong LIM

·      Mitochondria targeting drugs for neurodegenerative diseases-Design, mechanism and application

Su Chi LIM

·      Ethnic-Specific Type 2 Diabetes Risk Factor PAX4 R192H Is Associated with Attention-Specific Cognitive Impairment in Chinese with Type 2 Diabetes

·      Genetic risk score for plasma uric acid levels is associated with early rapid kidney function decline in type 2 diabetes

·      Roux-en-Y gastric bypass versus best medical treatment for type 2 diabetes mellitus in adults with body mass index between 27 and 32 kg/m 2: A 5-year randomized controlled trial

Dahai LUO

·      A loosened gating mechanism of RIG-I leads to autoimmune disorders

·      Dynamic Interactions of Post Cleaved NS2B Cofactor and NS3 Protease Identified by Integrative Structural Approaches

·      Intranasal Delivery of RIG-I Agonist Drives Pulmonary Myeloid Cell Activation in Mice

David LYE

·      External validation of the PRIORITY model in predicting COVID-19 critical illness in vaccinated and unvaccinated patients

·      The IDentif.AI-x pandemic readiness platform: Rapid prioritization of optimized COVID-19 combination therapy regimens

·      The Staphylococcus aureus Network Adaptive Platform Trial protocol: New tools for an old foe

Hiroshi MAKINO

·      Representation learning in the artificial and biological neural networks underlying sensorimotor integration

Reddy MOGALI

·      A systematic review: normative reference values of the median nerve cross-sectional area using ultrasonography in healthy individuals

Joanne NGEOW

·      Male breast cancer: a Singapore perspective

Michael NILSSON

·      Psychological Stress Management and Stress Reduction Strategies for Stroke Survivors: A Scoping Review

Parasuraman PADMANABHAN

·      3D culturing of human pluripotent stem cells-derived endothelial cells for vascular regeneration

Vivek PERUMAL

·      Ligamentum Teres Lesions Are Associated With Poorer Patient Outcomes in a Large Primary Hip Arthroscopy Cohort of 1,935 Patients

Kanyi PU

·      A Dual-Locked Activatable Phototheranostic Probe for Biomarker-Regulated Photodynamic and Photothermal Cancer Therapy

·      Catalytical nano-immunocomplexes for remote-controlled sono-metabolic checkpoint trimodal cancer therapy

Laurent RENIA

·      Discrepant serological findings in SARS-CoV-2 PCR negative, hospitalised patients with fever and acute respiratory symptoms during the pandemic

·      Evaluation of the safety and immunogenicity of different COVID-19 vaccine combinations in healthy individuals: study protocol for a randomized, subject-blinded, controlled phase 3 trial [PRIBIVAC]

·      Rapid microfluidic platform for screening and enrichment of cells secreting virus neutralizing antibodies

·      Vaccine breakthrough hypoxemic COVID-19 pneumonia in patients with auto-Abs neutralizing type I IFNs

Guy RUTTER

·      Autotaxin signaling facilitates β cell dedifferentiation and dysfunction induced by Sirtuin 3 deficiency

·      DRP1 levels determine the apoptotic threshold during embryonic differentiation through a mitophagy-dependent mechanism

·      In vivo and in vitro characterization of GL0034, a novel long-acting glucagon-like peptide-1 receptor agonist

·      Opposing effects on regulated insulin secretion of acute vs chronic stimulation of AMP-activated protein kinase

Yasunori SAHEKI

·      Special issue entitled Lipid transporters edited by Shamshad Cockcroft and Padinjat Raghu

Helen SMITH

·      Understanding the journeys of patients with an asthma exacerbation requiring urgent therapy at a primary care clinic

Maurice van STEENSEL / Tom CARNEY

·      Huriez syndrome: Additional pathogenic variants supporting allelism to SMARCAD syndrome

Mythily SUBRAMANIAM

·      Religiosity, Religious Coping and Distress Among Outpatients with Psychosis in Singapore

Joseph SUNG

·      Childhood antibiotics as a risk factor for Crohn's disease: The ENIGMA International Cohort Study

Andrew TAN / Christine CHEUNG

·      Endothelial-immune crosstalk contributes to vasculopathy in nonalcoholic fatty liver disease

Walter WAHLI

·      ATGL-dependent white adipose tissue lipolysis controls hepatocyte PPARα activity

Yulan WANG

·      CoIn: Correlation Induced Clustering for Cognition of High Dimensional Bioinformatics Data

Sunny WONG

·      3'untranslated regions of tumor suppressor genes evolved specific features to favor cancer resistance

·      SARS-CoV-2 non-structural protein 6 triggers NLRP3-dependent pyroptosis by targeting ATP6AP1

Yun XIA

·      Modelling AKI in vitro: taking organoids to the next level

·      When pooled CRISPR screen meets kidney organoids: towards identification of new genes and pathways

Tsin Wen YEO / Sapna SADARANGANI

·      Association of systemic vitamin D on the course of dengue virus infection in adults: a single-centre dengue cohort study at a large institution in Singapore

Rupesh AGRAWAL

• Author Response: Smokers' Choroidal Changes
• Presumed bilateral diffuse uveal melanocytic proliferation - A case report and review of literature

  Yusuf ALI / Per-Olof BERGGREN

• Local Dexamethasone Administration Delays Allogeneic Islet Graft Rejection in the Anterior Chamber of the Eye of Non-Human Primates

  Olivier BEAUCHET

• "Emergency Room Evaluation and Recommendations" and Incident Hospital Admissions in Older People with Major Neurocognitive Disorders Visiting Emergency Department: Results of an Experimental Study

  Josip CAR

• Lowering the Sampling Rate: Heart Rate Response during Cognitive Fatigue

  Pang CHEN

• Colorimetric microneedle patches for multiplexed transdermal detection of metabolites
• Starvation, Ferroptosis, and Prodrug Therapy Synergistically Enabled by a Cytochrome c Oxidase like Nanozyme

  Toh Hean CH’NG

• Editorial: Bidirectional Communication Between Synapses and Nucleus in Brain Physiology and Disease

  Sanjay CHOTIRMALL

• Population genomics confirms acquisition of drug-resistant Aspergillus fumigatus infection by humans from the environment
• Leveraging the Omics Revolution for Nontuberculous Mycobacteria Biomarkers
• Therapeutic Targeting of the Respiratory Microbiome
• Microbiomics Focused Data Integration: A Fresh Solve for the Rubik's Cube of Endophenotyping?
• Clinical Aspergillus Signatures in COPD and Bronchiectasis

  Jennifer CLELAND

• BMAT's predictive validity for medical school performance: a retrospective cohort study

  Jennifer CLELAND / Siew Ping HAN

• Feedback in online classes: Keeping it real-time

  Wilson GOH / Michael STANLEY-BAKER

• Data considerations for predictive modeling applied to the discovery of bioactive natural products

  Philip INGHAM

• Hedgehog signaling

  JingXuan KOH

• Purpose in Life in Older Adults: A Systematic Review on Conceptualization, Measures, and Determinants

  Jimmy LEE

• Haematological Changes and Adverse Events Associated with BNT162b2 mRNA COVID-19 Vaccine in Patients Receiving Clozapine - Findings from an Audit
• Utility and Barriers to Clozapine Use: A Joint Study of Clinicians' Attitudes From Singapore and Hong Kong

  Jimmy LEE / Andy HO

• Living Losses in Stroke Caregiving: A Qualitative Systematic Review of Systematic Reviews on Psycho-Socio-Emotional Challenges and Coping Mechanisms

  Franklin LEI

• Human NLRP1 is a sensor of pathogenic coronavirus 3CL proteases in lung epithelial cells

  Eng Sing LEE

• A cross-sectional study on the perceived barriers to physical activity and their associations with domain-specific physical activity and sedentary behaviour

  Su Chi LIM

• Association Between Use of Sodium-Glucose Co-Transporter-2 (SGLT2) Inhibitors and Cognitive Function in a Longitudinal Study of Patients with Type 2 Diabetes
• Roux-en-Y gastric bypass versus best medical treatment for type 2 diabetes mellitus in adults with body mass index between 27 and 32 kg/m 2: A 5-year randomized controlled trial
• Ethnic-Specific Type 2 Diabetes Risk Factor PAX4 R192H Is Associated with Attention-Specific Cognitive Impairment in Chinese with Type 2 Diabetes

  Marie LOH / John CHAMBERS

• Epigenome-wide association study of incident type 2 diabetes: a meta-analysis of five prospective European cohorts
• Author Correction: Identification of genetic effects underlying type 2 diabetes in South Asian and European populations
• DNA methylation signature of chronic low-grade inflammation and its role in cardio-respiratory diseases
• Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

  Dahai LUO

• A loosened gating mechanism of RIG-I leads to autoimmune disorders

  David LYE

• Sustaining Antimicrobial Stewardship in a High-Antibiotic Resistance Setting

  David LYE / Laurent RENIA

• Organ-specific immune response in lethal SARS-CoV-2 infection by deep spatial phenotyping

  Oon Tek NG

• Genomic surveillance uncovers ongoing transmission of carbapenem-resistant Acinetobacter baumannii (CRAB) and identifies actionable routes of transmissions in an endemic setting

  Kangyi PU

• Activatable cancer sono-immunotherapy using semiconducting polymer nanobodies

  Laurent RENIA / David LYE

• Antibody response of heterologous vs homologous mRNA vaccine boosters against the SARS-CoV-2 Omicron variant: interim results from the PRIBIVAC study, A Randomized Clinical Trial

  Guy A RUTTER

• Vertical Sleeve Gastrectomy Lowers SGLT2/Slc5a2 Expression in the Mouse Kidney
• DRP1 levels determine the apoptotic threshold during embryonic differentiation through a mitophagy-dependent mechanism

  Joseph SUNG

• Aberrant cholesterol metabolic signaling impairs antitumor immunosurveillance through natural killer T cell dysfunction in obese liver

  Cher Heng TAN

• Gadoxetate-Enhanced MRI as a Diagnostic Tool in the Management of Hepatocellular Carcinoma: Report from a 2020 Asia-Pacific Multidisciplinary Expert Meeting

  Ern Yu TAN

• Relevance of the MHC region for breast cancer susceptibility in Asians

  Navin Kumar VERMA

• Integrated Analysis of Cancer Tissue and Vitreous Humor from Retinoblastoma Eyes Reveals Unique Tumor-Specific Metabolic and Cellular Pathways in Advanced and Non-Advanced Tumors

  Yulan WANG

• Heme cross-feeding can augment Staphylococcus aureus and Enterococcus faecalis dual species biofilms

  Sunny WONG

• 3'untranslated regions of tumor suppressor genes evolved specific features to favor cancer resistance

  Tsin Wen YEO

• Efficacy and safety of two neutralising monoclonal antibody therapies, sotrovimab and BRII-196 plus BRII-198, for adults hospitalised with COVID-19 (TICO): a randomised controlled trial

  Yik Weng YEW

• Pattern of contact sensitisation in patients with and without atopic dermatitis in an Asian dermatology centre

Rupesh AGRAWAL

·      The application of clinical registries in ophthalmic trauma-the International Globe and Adnexal Trauma Epidemiology Study (IGATES)

·      Choroidal Microvascular Alterations in COVID-19 Patients

Yusuf ALI / Guy A RUTTER

·      Mitofusins Mfn1 and Mfn2 are Required to Preserve Glucose- But Not Incretin-Stimulated Beta Cell Connectivity and Insulin Secretion

Olivier BEAUCHET

·      Olfactory identification disorders due to Alzheimer's disease: A new test from France to Quebec

·      The prevention of major neurocognitive disorders in the next phase of COVID-19 pandemic: On being proactive

David BECKER

·      Wastewater sequencing uncovers early, cryptic SARS-CoV-2 variant transmission

·      Exploiting transposons in the study of Staphylococcus aureus pathogenesis and virulence

Stefan R BORNSTEIN

·      Schwann cell necroptosis in diabetic neuropathy

Lorainne Tudor CAR / Christian APFELBACHER 

·      Outcomes, Measurement Instruments, and Their Validity Evidence in Randomized Controlled Trials on Virtual, Augmented, and Mixed Reality in Undergraduate Medical Education: Systematic Mapping Review

Josip CAR

·      Clinical information quality of digital health technologies: protocol for an international eDelphi study

·      Reply to Ngoh et al. Comment on "Surendran et al. The Missed Opportunity of Patient-Centered Medical Homes to Thrive in an Asian Context. Int. J. Environ. Res. Public Health 2021, 18, 1817"

Josip CAR / Andy Hau Yan HO 

·      Acceptability and feasibility of a pilot randomized controlled trial of Narrative e-Writing Intervention (NeW-I) for parent-caregivers of children with chronic life-threatening illnesses in Singapore

John CHAMBERS

·      Real-time diabetic retinopathy screening by deep learning in a multisite national screening programme: a prospective interventional cohort study

·      Food environment and diabetes mellitus in South Asia: A geospatial analysis of health outcome data

Christine CHEUNG

·      Hypercoagulability, endotheliopathy, and inflammation approximating 1 year after recovery: Assessing the long-term outcomes in COVID-19 patients

Sing Yian CHEW

·      Delivery of Wnt inhibitor WIF1 via engineered polymeric microspheres promotes nerve regeneration after sciatic nerve crush

Sanjay H CHOTIRMALL 

·      Update in COVID-19 2021

Angela CHOW

·      The first nosocomial cluster of COVID-19 due to the Delta variant in a major acute-care hospital in Singapore - investigations and outbreak response

Jennifer CLELAND

·      Disruption in the space-time continuum: why digital ethnography matters

Rinkoo DALAN

·      Anastomosing Hemangioma on 68Ga-DOTATATE PET/CT: A Potential Pitfall

·      Reactive Oxygen Species Scavenging Nanomedicine for The Treatment of Ischemic Heart Disease

Konstadina GRIVA

·      The Interplay Between Strictness of Policies and Individuals' Self-Regulatory Efforts: Associations with Handwashing During the COVID-19 Pandemic

·      Understanding the psychosocial impact of colorectal cancer on young-onset patients: A scoping review

·      Effectiveness and acceptability of a multidisciplinary approach in improving the care of patients with advanced chronic kidney disease: a pilot study

Konstadina GRIVA / Josip CAR

·      Delphi Consensus on American Society of Anesthesiologists' Physical Status Classification in an Asian Tertiary Women's Hospital

Philip W INGHAM

·      Blood vessel occlusion by Cryptococcus neoformans is a mechanism for haemorrhagic dissemination of infection

Nagaendran KANDIAH

·      APOE4 and Confluent White Matter Hyperintensities Have a Synergistic Effect on Episodic Memory Impairment in Prodromal Dementia

Jimmy LEE 

·      Mapping genomic loci implicates genes and synaptic biology in schizophrenia

Kah Leong LIM

·      Prostaglandin A2 Interacts with Nurr1 and Ameliorates Behavioral Deficits in Parkinson's Disease Fly Model

Marie LOH / John CHAMBERS

·      Identification of genetic effects underlying type 2 diabetes in South Asian and European populations

Dahai LUO

·      Structure-Based Optimization and Characterization of Macrocyclic Zika Virus NS2B-NS3 Protease Inhibitors

·      Robust delivery of RIG-I agonists using extracellular vesicles for anti-cancer immunotherapy

David C LYE

·      Remdesivir for the prevention of invasive mechanical ventilation or death in COVID-19 - A post-hoc analysis of the Adaptive COVID-19 Treatment Trial-1 Cohort Data

·      Global haemostatic tests demonstrate the absence of parameters of hypercoagulability in non-hypoxic mild COVID-19 patients: a prospective matched study

·      Comparative Effectiveness of mRNA and Inactivated Whole Virus Vaccines against COVID-19 Infection and Severe Disease in Singapore

·      Virological and serological kinetics of SARS-CoV-2 Delta variant vaccine-breakthrough infections: a multi-center cohort study

Joanne NGEOW

·      Male breast cancer: a Singapore perspective

Laurent RENIA

·      Improving in vitro continuous cultivation of Plasmodium cynomolgi, a model for P. vivax

·      Studying severe long COVID to understand post-infectious disorders beyond COVID-19

·      Rosetting Responses of Plasmodium-infected Erythrocytes to Antimalarials

Richard REYNOLDS

·      Diverse pathways to neuronal necroptosis in Alzheimer's disease

Guy A RUTTER

·      Glucose-Dependent miR-125b is a Negative Regulator of β-Cell Function

·      Autotaxin signaling facilitates β cell dedifferentiation and dysfunction induced by Sirtuin 3 deficiency

Helen SMITH

·      The impact and applications of social media platforms for public health responses before and during COVID-19

·      Medical students' attitudes towards and views of general practice careers in Singapore: a cross-sectional survey and qualitative analysis

Maurice A M van STEENSEL

·      Comment on Balsamo et al.: Birt-Hogg-Dubé syndrome with simultaneous hyperplastic polyposis of the gastrointestinal tract: case report and review of the literature

Joseph J Y SUNG

·      Magnetic Microswarm and Fluoroscopy-Guided Platform for Biofilm Eradication in Biliary Stents

·      Mechanistic insight of SARS-CoV-2 infection using human hepatobiliary organoids

Ern Yu TAN / Joanne NGEOW

·      Overlap of high-risk individuals predicted by family history, and genetic and non-genetic breast cancer risk prediction models: implications for risk stratification

Nguan Soon TAN

·      N-WASP Attenuates Cell Proliferation and Migration through ERK2-Dependent Enhanced Expression of TXNIP

Nguan Soon TAN / Christine CHEUNG 

·      Endothelial-immune crosstalk contributes to vasculopathy in nonalcoholic fatty liver disease

Walter WAHLI

·      Integrative study of diet-induced mouse models of NAFLD identifies PPARα as a sexually dimorphic drug target

·      The hepatocyte insulin receptor is required to program the liver clock and rhythmic gene expression

Sunny H WONG

·      An update on the roles of circular RNAs in spinal cord injury

Yik Weng YEW

·      Hand hygiene and hand eczema: a systematic review and meta-analysis

Rupesh AGRAWAL

·      Longitudinal analysis of the retina and choroid in cognitively normal individuals at higher genetic risk for Alzheimer disease

·      Three-dimensional modelling of the choroidal angioarchitecture in a multi-ethnic Asian population

·      Automated lesion segmentation and quantification for prediction of paradoxical worsening in patients with tubercular serpiginous-like choroiditis

Yusuf ALI / Sunny H WONG

·      Stress Hyperglycemia Is Associated With an Increased Risk of Subsequent Development of Diabetes Among Bacteremic and Nonbacteremic Patients

Christian APFELBACHER 

·      The HOME Core outcome set for clinical trials of atopic dermatitis

Olivier BEAUCHET 

·      Frailty, e-health and prevention of late-onset Alzheimer disease and related disorders: it is time to take action

Per-Olof BERGGREN

·      Intravital Ca 2+ imaging of pancreatic β cell function after bariatric surgery

·      HIF-1α inhibitor PX-478 preserves pancreatic β cell function in diabetes

Bernhard O BOEHM 

·      Insulin Allergy to Detemir Followed by Rapid Onset of Diabetic Ketoacidosis: A Case Report and Literature Review

Stefan R BORNSTEIN

·      Rubicon-deficiency sensitizes mice to mixed lineage kinase domain-like (MLKL)-mediated kidney ischemia-reperfusion injury

Josip CAR

·      Global, regional, and national burden of diseases and injuries for adults 70 years and older: systematic analysis for the Global Burden of Disease 2019 Study

·      Health app policy: international comparison of nine countries' approaches

Lorainne Tudor CAR

·      Diabetes mortality and trends before 25 years of age: an analysis of the Global Burden of Disease Study 2019

Lorainne Tudor CAR / Josip CAR

·      Digital Education for Health Professionals: An Evidence Map, Conceptual Framework, and Research Agenda

Lorainne Tudor CAR / Jimmy LEE / Konstadina GRIVA / Josip CAR

·      Education on Depression in Mental Health Apps: Systematic Assessment of Characteristics and Adherence to Evidence-Based Guidelines

Tom CARNEY

·      Colorimetric and fluorescent TRAP assays for visualising and quantifying fish osteoclast activity

Annabel CHEN

·      Aging Patterns of Japanese Auditory Semantic Processing: An fMRI Study

Christine CHEUNG

·      Left Atrial Phasic Function in Older Adults Is Associated with Fibrotic and Low-Grade Inflammatory Pathways

Sanjay H CHOTIRMALL

·      Microbiology and the Microbiome in Bronchiectasis

·      The Current Understanding and Future Directions for Sputum Microbiome Profiling in Chronic Obstructive Pulmonary Disease

·      Association of nanoparticle exposure with serum metabolic disorders of healthy adults in printing centers

·      Distance-Based Detection of Cough, Wheeze, and Breath Sounds on Wearable Devices

Angela CHOW

·      Systematic Review of Determinants Influencing Antibiotic Prescribing for Uncomplicated Acute Respiratory Tract Infections in Adult Patients at the Emergency Department

·      Fending off Delta - Hospital measures to reduce nosocomial transmission of COVID-19

·      Public perception on the use of digital contact tracing tools post COVID-19 lockdown: Sentiment analysis and opinion mining

·      Determinants of the acceptance and adoption of a digital contact tracing tool during the COVID-19 pandemic in Singapore

·      Synergistic effects of length of stay and prior MDRO carriage on the colonization and co-colonization of methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus, and carbapenemase-producing Enterobacterales across healthcare settings

Toh Hean CH’NG

·      Distinct contributions of ventral CA1/amygdala co-activation to the induction and maintenance of synaptic plasticity

·      Sex matters in Alzheimer's disease?

Jennifer CLELAND

·      Promoting inclusivity in health professions education publishing

Rinkoo DALAN

·      SARS-CoV-2 mRNA Vaccination and Graves' Disease: a report of 12 cases and review of the literature

Wilson Wen Bin GOH

·      How Doppelgänger Effects in Biomedical Data Confound Machine Learning

·      Are batch effects still relevant in the age of big data?

Jia Nee FOO / Sunny Hei WONG / Nguan Soon TAN / Guy A RUTTER / Per-Olof Berggren / Yusuf ALI

·      Destabilization of β Cell FIT2 by saturated fatty acids alter lipid droplet numbers and contribute to ER stress and diabetes

Balázs GULYÁS

·      The Exoproteome of Staphylococcus pasteuri Isolated from Cervical Mucus during the Estrus Phase in Water Buffalo ( Bubalus bubalis)

·      Differential effects of white matter hyperintensities and regional amyloid deposition on regional cortical thickness

Han Wei HOU

·      Microfluidic Impedance-Deformability Cytometry for Label-Free Single Neutrophil Mechanophenotyping

Nagaendran KANDIAH

·      Alzheimer's Disease THErapy With NEuroaid (ATHENE): A Randomized Double-Blind Delayed-Start Trial

·      Safety and Usefulness of Lumbar Puncture for the Diagnosis and Management of Young-Onset Cognitive Disorders

Sarah R LANGLEY

·      Ermin deficiency leads to compromised myelin, inflammatory milieu, and susceptibility to demyelinating insult

·      Association of ultra-rare coding variants with genetic generalized epilepsy: A case-control whole exome sequencing study

Eng Sing LEE

·      Factors associated with family caregiver burden among frail older persons with multimorbidity

Jimmy LEE

·      Social skills, negative symptoms and real-world functioning in individuals at ultra-high risk of psychosis

·      Defining negative symptoms remission in schizophrenia using the Brief Negative Symptom Scale

Melvin Khee-Shing LEOW

·      Brown adipose tissues mediate the metabolism of branched chain amino acids during the transitioning from hyperthyroidism to euthyroidism (TRIBUTE)

Chin Leong LIM

·      Systemic Lactate Elevation Induced by Tobacco Smoking during Rest and Exercise Is Not Associated with Nicotine

David LYE

·      Real-World Use of Sotrovimab for Pre-Emptive Treatment in High-Risk Hospitalized COVID-19 Patients: An Observational Cross-Sectional Study

Joanne NGEOW / Yun XIA

·      Studying Kidney Diseases Using Organoid Models

Oon Tek NG

·      Population-based variations of a core resistome revealed by urban sewage metagenome surveillance

·      Impact of SARS-CoV-2 Vaccination and Paediatric Age on Delta Variant Household Transmission

Michael NILSSON

·      Correction: Assessing the Efficacy of an Individualized Psychological Flexibility Skills Training Intervention App for Medical Student Burnout and Well-being: Protocol for a Randomized Controlled Trial

Kevin PETHE

·      Sensitivity of Mycobacterium leprae to Telacebec

Kanyi PU

·      Semiconducting Polymer Nanoparticles for Photoactivatable Cancer Immunotherapy and Imaging of Immunoactivation

·      Semiconducting Polymer Nano-regulators with Cascading Activation for Photodynamic Cancer Immunotherapy

Laurent RENIA

·      Human Genetic and Immunological Determinants of Critical COVID-19 Pneumonia

·      Selection of O-negative induced pluripotent stem cell clones for high-density red blood cell production in a scalable perfusion bioreactor system

·      Decreased Memory B Cells Frequencies in COVID-19 Delta Variant Vaccine Breakthrough Infection

Jerome I ROTGANS

·      Failure to demonstrate effects of interruptions on diagnostic reasoning: three experiments

Guy A RUTTER

·      Opposing effects on regulated insulin secretion of acute vs chronic stimulation of AMP-activated protein kinase

Yasunori SAHEKI

·      Special issue entitled Lipid transporters edited by Shamshad Cockcroft and Padinjat Raghu

Joseph J Y SUNG

·      Micro-/Nanorobots in Antimicrobial Applications: Recent Progress, Challenges, and Opportunities

·      Squalene epoxidase drives cancer cell proliferation and promotes gut dysbiosis to accelerate colorectal carcinogenesis

Hong Liang TEY

·      Skin-ny Deeping: Uncovering Immune Cell Behavior and Function Through Imaging Techniques

·      Systemic Inflammatory Reactions After COVID-19 Vaccinations: Consider the Diagnosis of ASIA

·      Subsurface Detection of Hair Follicles in Alopecia Areata Using Optical Coherence Tomography

·      Transitional premonocytes emerge in the periphery for host defense against bacterial infections

Ranganath VALLABHAJOSYULA

·      The Use of Mobile Games in the Management of Patients With Attention Deficit Hyperactive Disorder: A Scoping Review

Walter WAHLI

·      Nuclear HMGB1 protects from nonalcoholic fatty liver disease through negative regulation of liver X receptor

Yik Weng YEW

·      Effect of Vitamin D Serum Levels and Supplementation on Atopic Dermatitis: A Systematic Review and Meta-analysis

Steve Hung Lam YIM

·      What drives long-term PM 2.5-attributable premature mortality change? A case study in central China using high-resolution satellite data from 2003 to 2018

 Rupesh AGRAWAL

·       Outcome Measures for Disease Monitoring in Intraocular Inflammatory and Infectious Diseases (OCTOMERIA): Understanding the Choroid in Uveitis with Optical Coherence Tomography (OCT).

Stefan BORNSTEIN

·       Dexamethasone sensitizes to ferroptosis by glucocorticoid receptor-induced dipeptidase-1 expression and glutathione depletion.

Lorainne Tudor CAR 

·       Diabetes mortality and trends before 25 years of age: an analysis of the Global Burden of Disease Study 2019.

Lorainne Tudor CAR / Reddy Mogali 

 ·       Virtual Reality in Medical Students' Education: Scoping Review.

John CHAMBERS

·       Sex differences in right ventricular systolic function and all-cause mortality in tricuspid regurgitation.

John CHAMBERS / Marie LOH

 ·       Epigenome-wide association study of incident type 2 diabetes: a meta-analysis of five prospective European cohorts.

George CHANDY

·       Rearrangement of a unique Kv1.3 selectivity filter conformation upon binding of a drug.

Christine CHEUNG / Norris Ray DUNN / HOU Han Wei

 ·       Hyaluronidase-1-mediated glycocalyx impairment underlies endothelial abnormalities in polypoidal choroidal vasculopathy.

Sanjay CHOTIRMALL

·       Treatment Trials in Young Patients with COPD and Pre-COPD Patients: Time to Move Forward.

Angela CHOW 

 ·       Fending off Delta - Hospital measures to reduce nosocomial transmission of COVID-19.

Jennifer CLELAND

 ·       Differential attainment at MRCS according to gender, ethnicity, age and socioeconomic. factors: a retrospective cohort study

Jennifer CLELAND / Lucy ROSBY / Helen SMITH / Naomi LOW-BEER

·       Student assistantship programme: an evaluation of impact on readiness to transit from medical student to junior doctor.

Jennifer CLELAND / HAN Siew Ping

·       Feedback in online classes: Keeping it real-time.

Rinkoo DALAN / Bernhard BOEHM

·       Micronutrient supplementation before COVID-19 vaccination can protect against adverse effects.

Wilson GOH 

·       Proteomic datasets of HeLa and SiHa cell lines acquired by DDA-PASEF and diaPASEF.

Konstadina GRIVA 

·       Understanding the psychosocial impact of colorectal cancer on young-onset patients: A scoping review.

Balázs GULYAS

·       Gadolinium and Polythiophene Functionalized Polyurea Polymer Dots as Fluoro-Magnetic Nanoprobes.

Jimmy LEE 

·       Impact of Negative Symptoms on Functioning and Quality of Life in First Psychotic Episodes of Schizophrenia.

LUO Dahai

·       A conserved arginine in NS5 binds genomic 3' stem-loop RNA for primer-independent initiation of flavivirus RNA replication.

David LYE 

·       Robust Virus-Specific Adaptive Immunity in COVID-19 Patients with SARS-CoV-2 Δ382 Variant Infection.

·       Validation of ISARIC 4C mortality and deterioration scores in a mixed vaccination status cohort of hospitalized COVID-19 patients in Singapore.

·       External validation of the PRIORITY model in predicting COVID-19 critical illness in vaccinated and unvaccinated patients.

Michael NILSSON

·       Assessing the Efficacy of an Individualized Psychological Flexibility Skills Training Intervention App for Medical Student Burnout and Well-being: Protocol for a Randomized Controlled Trial.

Preman RAJALINGAM / Emmanuel Tan

·       Effect of Seating Arrangement on Class Engagement in Team-based Learning: a Quasi-Experimental Study.

Laurent RENIA 

·       Discrepant serological findings in SARS-CoV-2 PCR negative, hospitalised patients with fever and acute respiratory symptoms during the pandemic.

Helen SMITH

·       The impact and applications of social media platforms for public health responses before and during COVID-19.

·       Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.

Maurice van STEENSEL / Tom CARNEY 

·       Huriez syndrome: Additional pathogenic variants supporting allelism to SMARCAD syndrome.

Joseph SUNG

·       The use of topical mineral powder as monotherapy for treatment of active peptic ulcer bleeding.

·       Altered gut metabolites and microbiota interactions are implicated in colorectal carcinogenesis and can be non-invasive diagnostic biomarkers.

Andrew TAN 

·       Single-cell analysis of skin immune cells reveals an Angptl4-ifi20b axis that regulates monocyte differentiation during wound healing.

TAN Ern Yu 

·       Predicting the Likelihood of Carrying a BRCA1 or BRCA2 Mutation in Asian Patients With Breast Cancer.

Navin VERMA 

·       Rationalisation of Antifungal Properties of α-Helical Pore-Forming Peptide, Mastoparan B.

Walter WAHLI 

·       Role of Dietary Supplements and Probiotics in Modulating Microbiota and Bone Health: The Gut-Bone Axis.

WANG Yulan 

·       Quantitative structure-retention relationship for reliable metabolite identification and quantification in metabolomics using ion-pair reversed-phase chromatography coupled with tandem mass spectrometry.

Sunny WONG

·       An update on the roles of circular RNAs in spinal cord injury.

·       Emerging Roles of Long Non-Coding RNAs in Ankylosing Spondylitis.

Eric YAP  

·       Effects of age, sex, serostatus, and underlying comorbidities on humoral response post-SARS-CoV-2 Pfizer-BioNTech mRNA vaccination: a systematic review.

YEO Tsin Wen

·       Responses to a Neutralizing Monoclonal Antibody for Hospitalized Patients With COVID-19 According to Baseline Antibody and Antigen Levels : A Randomized Controlled Trial.

YEW Yik Weng 

·       Pattern of contact sensitisation in patients with and without atopic dermatitis in an Asian dermatology centre.

Steve YIM

 ·       What drives long-term PM 2.5-attributable premature mortality change? A case study in central China using high-resolution satellite data from 2003 to 2018.

Rupesh AGRAWAL

• Ocular inflammatory events following COVID-19 vaccination: a multinational case series.
• International Globe and Adnexal Trauma Epidemiology Study (IGATES): Visual outcomes in open globe injuries in rural West India.
• Multifocal Serpiginoid Choroiditis Due to Mycobacterium Mageritense following Laparoscopic Hysterectomy in an Immunocompetent Host.
• Global Current Practice Patterns for the Management of Central Retinal Artery Occlusion.

Olivier BEAUCHET

• "Emergency Room Evaluation and Recommendations" (ER2) Tool for the Screening of Older Emergency Department Visitors With Major Neurocognitive Disorders: Results From the ER 2 Database.

Lorainne Tudor CAR

• Digital Behavior Change Interventions for the Prevention and Management of Type 2 Diabetes: Systematic Market Analysis.

John CHAMBERS

• Genetic variation influencing DNA methylation provides insights into molecular mechanisms regulating genomic function.

   

  George CHANDY

   

• Histone acetylome-wide associations in immune cells from individuals with active Mycobacterium tuberculosis infection.

   

  Victoria LEONG / Annabel CHEN

   

• A New Remote Guided Method for Supervised Web-Based Cognitive Testing to Ensure High-Quality Data: Development and Usability Study.

Sanjay CHOTIRMALL

• High Frequency of Allergic Bronchopulmonary Aspergillosis in Bronchiectasis-COPD Overlap.
• Bronchiectasis. (Book Chapter)

   

  Angela CHOW​

   

  • Seroprevalence of IgG antibodies against diphtheria antitoxin among migrant workers in Singapore, 2016-2019.
  • Prevalence of measles antibodies among migrant workers in Singapore: a serological study to identify susceptible population subgroups.
  • Public perception on the use of digital contact tracing tools post COVID-19 lockdown: Sentiment analysis and opinion mining.

     

    Jennifer CLELAND

• Does performance at the intercollegiate Membership of the Royal Colleges of Surgeons (MRCS) examination vary according to UK medical school and course type? A retrospective cohort study.
• Won't you stay just a little bit longer? A discrete choice experiment of UK doctors' preferences for delaying retirement.

   

   

  Rinkoo DALAN

• Thymosin beta-4 improves endothelial function and reparative potency of diabetic endothelial cells differentiated from patient induced pluripotent stem cells.
• Anastomosing Hemangioma on 68Ga-DOTATATE PET/CT: A Potential Pitfall.

  Rinkoo DALAN / HOU Han Wei

• Microfluidic Size Exclusion Chromatography (μSEC) for Extracellular Vesicles and Plasma Protein Separation.

  DUAN Hongwei

   

• Localized Degradation of Neutrophil Extracellular Traps by Photoregulated Enzyme Delivery for Cancer Immunotherapy and Metastasis Suppression.

   

  FOO Jia Nee

   

• RIC3 variants are not associated with Parkinson's disease in large European, Latin American, or East Asian cohorts.

   

  Wilson GOH

   

• PROTREC: A probability-based approach for recovering missing proteins based on biological networks.

Balazs GULYAS

• Positron emission tomographic imaging in drug discovery.
• The Multifarious Applications of Copper Nanoclusters in Biosensing and Bioimaging and Their Translational Role in Early Disease Detection.

   

  Jimmy LEE​

   

• Impact of drug-induced Parkinsonism and tardive dyskinesia on health-related quality of life in schizophrenia.

   

   

  LUO Dahai

   

• Crystal structures of alphavirus nonstructural protein 4 (nsP4) reveal an intrinsically dynamic RNA-dependent RNA polymerase fold.

   

  David LYE

   

• Antibiotic Therapy in the Treatment of COVID-19 Pneumonia: Who and When?

   

  Kevin PETHE

   

• Turbidity-Based MIC Assay and Characterization of Spontaneous Drug Resistant Mutants in Mycobacterium ulcerans.
• Determination of Bioenergetic Parameters in Mycobacterium ulcerans.
• Telacebec: an investigational antibiotic for the treatment of tuberculosis (TB).

Laurent RENIA

• Decreased memory B cells frequencies in COVID-19 Delta variant vaccine breakthrough infection.
• Malaria abrogates O'nyong-nyong virus pathologies by restricting virus infection in nonimmune cells.
• Cytoadherence Properties of Plasmodium knowlesi-Infected Erythrocytes.
• Human genetic and immunological determinants of critical COVID-19 pneumonia.

   

  Richard REYNOLDS

   

• Increased expression of pathological markers in Parkinson's disease dementia post-mortem brains compared to dementia with Lewy bodies.

   

  Guy RUTTER

• Editorial: Pancreas Imaging Across the Spectrum.

Joseph SUNG

• .Sirtuin 7 super-enhancer drives epigenomic reprogramming in hepatocarcinogenesis.

   

  Andrew TAN​

   

• Noninvasive and Point-of-Care Surface-Enhanced Raman Scattering (SERS)-Based Breathalyzer for Mass Screening of Coronavirus Disease 2019 (COVID-19) under 5 min.
• Modulated TRPC1 Expression Predicts Sensitivity of Breast Cancer to Doxorubicin and Magnetic Field Therapy: Segue Towards a Precision Medicine Approach.

   

  TAN Chin Hong

• Interactions of comorbid neuropsychiatric subsyndromes with neurodegenerative and cerebrovascular pathologies on cognition.

  TEY Hong Liang​

   

• Subsurface detection of hair follicles in alopecia areata using optical coherence tomography.

   

  Sunny WONG

• Vitamin D 3 and carbamazepine protect against Clostridioides difficile infection in mice by restoring macrophage lysosome acidification.
• SARS-CoV-2 non-structural protein 6 triggers NLRP3-dependent pyroptosis by targeting ATP6AP1.
• Circular RNAs in Intervertebral Disc Degeneration: An Updated Review.
• SARS-CoV-2 targets the lysosome to mediate airway inflammatory cell death.

Rupesh AGRAWAL

• Semi-automated quantitative analysis of the middle limiting membrane in tubercular serpiginous-like choroiditis using swept-source optical coherence tomography.
• Global Preferred Practice Patterns for the Management of Exogenous Endophthalmitis: A Survey by the American Society of Ophthalmic Trauma.
• The Eye of the Storm: COVID-19 Vaccination and the Eye.
• Eye Care During the COVID-19 Pandemic: A Report on Patients' Perceptions and Experiences, an Asian Perspective.
• Clinical characteristics and treatment outcomes of Cytomegalovirus anterior uveitis and endotheliitis: a systematic review and meta-analysis.

• Colorimetric and Fluorometric Profiling of Advanced Glycation End Products.

• Traversing Boundaries: New Digital Project to Study Drugs in Asian History by Yan Liu.

• Experiences, opinions and expectations of health care providers towards an intensive care unit follow-up clinic: Qualitative study and online survey.

• Vitamin D Supplementation and Cognition in Adults: A Systematic Review of Randomized Controlled Trials.
• Effects of Memantine and High Dose Vitamin D on Gait in Male APP/PS1 Alzheimer's Disease Mice Following Vitamin D Deprivation.

• Conversational Agent for Healthy Lifestyle Behavior Change: Web-Based Feasibility Study.

• Health-related quality of life and chronic wound characteristics among patients with chronic wounds treated in primary care: A cross-sectional study in Singapore.

• Complex Lifestyle and Psychological Intervention in Knee Osteoarthritis: Scoping Review of Randomized Controlled Trials.

• Delphi Consensus on American Society of Anesthesiologists' Physical Status Classification in an Asian Tertiary Women's Hospital.

• Meta-analyses identify DNA methylation associated with kidney function and damage.
• The power of genetic diversity in genome-wide association studies of lipids.

• The iHealth-T2D study, prevention of type 2 diabetes amongst South Asians with central obesity and prediabetes: study protocol for a randomised controlled trial.

• Reverse-translational identification of a cerebellar satiation network.
• Sex-specific accelerated decay in time/activity-dependent plasticity and associative memory in an animal model of Alzheimer's disease.

• Neural Cell Membrane-Coated Nanoparticles for Targeted and Enhanced Uptake by Central Nervous System Cells.

• Comparing hospital-resource utilization by an enhanced pneumonia surveillance programme for COVID-19 with pre-pandemic pneumonia admissions - a Singaporean hospital's experience.
• The first nosocomial cluster of COVID-19 due to the Delta variant in a major acute-care hospital in Singapore - investigations and outbreak response.
• Sociodemographic and clinical factors, visit expectations and driving factors for emergency department attendance for uncomplicated upper respiratory tract infection.
• Antibiotic Expectations of Emergency Department Patients with Upper Respiratory Tract Infections: Clinical and Antibiotic Use Behavioral Determinants.

• When I say … privilege.
• The do's, don'ts and don't knows of redressing differential attainment related to race/ethnicity in medical schools.

• Noninvasive follicular thyroid neoplasm with papillary-like nuclear features and the risk of malignancy in thyroid cytology: Data from Singapore.

• A Facile and Scalable Hydrogel Patterning Method for Microfluidic 3D Cell Culture and Spheroid-in-Gel Culture Array.

• Technological advancements in the assessment and intervention of developmental disabilities.
• Clarifying the relationship between alexithymia and subjective interception.

• Treatment-related decisional conflict in pre-dialysis chronic kidney disease patients in Singapore: Prevalence and determinants.
• The Interplay Between Strictness of Policies and Individuals' Self-Regulatory Efforts: Associations with Handwashing During the COVID-19 Pandemic.

• Neural correlates of state transitions elicited by a chemosensory danger cue.

• Comparative study of emotion recognition and theory of mind between major depressive disorder and schizophrenia.

• Lessons From Heat Stroke for Understanding Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.

• Conditional disruption of AMP kinase in dopaminergic neurons promotes Parkinson's disease-associated phenotypes in vivo.

• Epigenome-wide association study of serum urate reveals insights into urate co-regulation and the SLC2A9 locus.

• Investigator-Driven Randomised Controlled Trial of Cefiderocol versus Standard Therapy for Healthcare-Associated and Hospital-Acquired Gram-negative Bloodstream Infection: Study protocol (the GAME CHANGER trial): study protocol for an open-label, randomised controlled trial.

• Impact of Delta Variant and Vaccination on SARS-CoV-2 Secondary Attack Rate Among Household Close Contacts.

• Understanding patients' views and willingness toward the use of telehealth in a cancer genetics service in Asia.
• Germline breast cancer susceptibility genes, tumor characteristics, and survival.

• Learning to diagnose X-rays: a neuroscientific study of practice-related activation changes in the prefrontal cortex.

• Aberrant Wnt Signaling Induces Comedo-Like Changes in The Murine Upper Hair Follicle.

• Micro-/Nanorobots in Antimicrobial Applications: Recent Progress, Challenges, and Opportunities.

• Trends in Incidence and Clinical Outcomes of Clostridioides difficile Infection, Hong Kong.

• Bioinspired short peptide hydrogel for versatile encapsulation and controlled release of growth factor therapeutics.

• In Vivo Efficacy of Neutrophil-Mediated Bone Regeneration Using a Rabbit Calvarial Defect Model.
• Marine collagen scaffolds in tissue engineering.

• Skin-ny deeping: Uncovering immune cell behavior and function through imaging techniques.
• Systemic inflammatory reactions after COVID-19 vaccinations: Consider the diagnosis of ASIA.

• GSK3β Interacts With CRMP2 and Notch1 and Controls T-Cell Motility.

• RTP: One Effective Platform to Probe Reactive Compound Transformation Products and Its Applications for a Reactive Plasticizer BADGE.

• Insights into potential causes of vascular hyperpermeability in dengue.
• Efficacy and safety of two neutralising monoclonal antibody therapies, sotrovimab and BRII-196 plus BRII-198, for adults hospitalised with COVID-19 (TICO): a randomised controlled trial.

• The Historical Evolution of Ocular Tuberculosis: Past, Present, and Future.
• The application of clinical registries in ophthalmic trauma-the International Globe and Adnexal Trauma Epidemiology Study (IGATES).
• Redefining response in wet AMD to anti VEGF therapy based on non-OCTA versus OCTA evaluation.

• Robotic-based ACTive somatoSENSory (Act.Sens) retraining on upper limb functions with chronic stroke survivors: study protocol for a pilot randomised controlled trial.

• Frequency of hand eczema in the elderly - cross-sectional findings from the German AugUR study.

• A wireless and battery-free wound infection sensor based on DNA hydrogel.

• COVID-19 and metabolic disease: mechanisms and clinical management.

• The importance of air quality for underground spaces: An international survey of public attitudes.
• Revisiting the four core functions (4Cs) of primary care: operational definitions and complexities.

• Label-free quantitative measurement of cardiovascular dynamics in a zebrafish embryo using frequency-comb-referenced-quantitative phase imaging.
• Tetraspanin Cd9b and Cxcl12a/Cxcr4b have a synergistic effect on the control of collective cell migration.

• Corrigendum: Elena+ Care for COVID-19, a Pandemic Lifestyle Care Intervention: Intervention Design and Study Protocol.

• Effects of a lifestyle intervention programme after 1 year of follow-up among South Asians at high risk of type 2 diabetes: a cluster randomised controlled trial.

• A Parametric Framework to Generate Visual Illusions Using Python.

• Cellular Features Revealed by Transverse Laser Modes in Frequency Domain.

Sanjay CHOTIRMALL

• The current understanding and future directions for sputum microbiome profiling in chronic obstructive pulmonary disease.

• Mathematical-based microbiome analytics for clinical translation.

• Psychological impact of repeated epidemic exposure on healthcare workers: findings from an online survey of a healthcare workforce exposed to both SARS (severe acute respiratory syndrome) and COVID-19.

• Hospital Pharmacists and Antimicrobial Stewardship: A Qualitative Analysis.

• A cross-sectional study examining MRCS performance by core surgical training location.
• Implementing change: Intervention development.
• Even a little sleepiness influences neural activation and clinical reasoning in novices.

• Cameras on or off: What is the question?

• Professional development during the COVID-19 pandemic: Crisis or opportunity?

• Reduced Perceived Trustworthiness during Face Mask Wearing.
• Surveying 80 Years of Psychodrama Research: A Scientometric Review.
• I'm alone but not lonely. U-shaped pattern of self-perceived loneliness during the COVID-19 pandemic in the UK and Greece.

• Evaluating Rates and Determinants of COVID-19 Vaccine Hesitancy for Adults and Children in the Singapore Population: Strengthening Our Community's Resilience against Threats from Emerging Infections (SOCRATEs) Cohort.

• Public Perceptions of Diabetes, Healthy Living, and Conversational Agents in Singapore: Needs Assessment.

• The bacterial tyrosine kinase system CpsBCD governs the length of capsule polymers.

• Anticancer Potential of L-Histidine-Capped Silver Nanoparticles against Human Cervical Cancer Cells (SiHA).

• Dementia in Southeast Asia: influence of onset-type, education, and cerebrovascular disease.
• Alzheimer's Disease THErapy With NEuroaid (ATHENE): A Randomized Double-Blind Delayed-Start Trial.

• Clinical- and omics-based models of subclinical atherosclerosis in healthy Chinese adults: a cross-sectional exploratory study.
• Branched Chain Amino Acid Supplementation to a Hypocaloric Diet Does Not Affect Resting Metabolic Rate but Increases Postprandial Fat Oxidation Response in Overweight and Obese Adults after Weight Loss Intervention.

• Viral dynamics and immune correlates of COVID-19 disease severity.
• Correction to: Robust Virus-Specific Adaptive Immunity in COVID-19 Patients with SARS-CoV-2 Δ382 Variant Infection.
• Virological and serological kinetics of SARS-CoV-2 Delta variant vaccine-breakthrough infections: a multi-center cohort study.
• Data-Driven Analysis of COVID-19 Reveals Persistent Immune Abnormalities in Convalescent Severe Individuals.

• Lack of viable SARS-CoV-2 among PCR-positive air samples from hospital rooms and community isolation facilities.

• Author Correction: PRL3-zumab as an immunotherapy to inhibit tumors expressing PRL3 oncoprotein.
• Impact of Variant Reclassification in Cancer Predisposition Genes on Clinical Care.

• The QcrB inhibitors TB47 and telacebec do not potentiate the activity of clofazimine in Mycobacterium abscessus.

• Irritable bowel syndrome and risk of glaucoma: An analysis of two independent population-based cohort studies.

• Renal-Clearable Molecular Probe for Near-Infrared Fluorescence Imaging and Urinalysis of SARS-CoV-2.

• Plasmodium falciparum rosetting protects schizonts against artemisinin.

• Dysregulation of the Pdx1/Ovol2/Zeb2 axis in dedifferentiated β-cells triggers the induction of genes associated with epithelial-mesenchymal transition in diabetes.
• Distinct Molecular Signatures of Clinical Clusters in People with Type 2 Diabetes: an IMIRHAPSODY Study.

• Correction to: A mobile swabbing booth to address Singapore GPs' concerns about swabber protection: human-centred design during the COVID-19 pandemic.
• Experiences of doctors working in Singapore's public primary healthcare clinics.
• Aspirin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.

• Priorities for family physician and general practitioner recruitment and retention in Singapore: a PRIORITIZE study.

• Inherited skin disorders presenting with poikiloderma.

• Circulating microRNA Breast Cancer Biomarker Detection in Patient Sera with Surface Plasmon Resonance Imaging Biosensor.

• Chelating Phosphine-N-Heterocyclic Carbene Platinum Complexes via Catalytic Asymmetric Hydrophosphination and Their Cytotoxicity Toward MKN74 and MCF7 Cancer Cell Lines.

• Non-Bullous Pemphigoid: A Yet-to-Be Defined Disease Entity.
• Response to: Momen et al's "Discriminating minor and major forms of drug reaction with eosinophilia and systemic symptoms: Facial edema aligns to the severe phenotype".

• The steroidal lactone withaferin A impedes T-cell motility by inhibiting the kinase ZAP70 and subsequent kinome signaling.

• Assessment of Discrepancies Between Follow-up Infarct Volume and 90-Day Outcomes Among Patients With Ischemic Stroke Who Received Endovascular Therapy.

• Malaria in Pregnancy: From Placental Infection to Its Abnormal Development and Damage.

• Bilateral Pupillary Involvement as a Clinical Presentation of Herpes Zoster Ophthalmicus.
• Myopic Shift in a Patient with Dengue Fever.

• Enhanced postoperative surveillance versus standard of care to reduce mortality among adult surgical patients in Africa (ASOS-2): a cluster-randomised controlled trial.

• Microglia and CD206 + border-associated mouse macrophages maintain their embryonic origin during Alzheimer's disease.

• Emergency room evaluation and recommendations for older emergency department users: results of the ER 2 experimental study.

• Extracellular matrix and cellular senescence in venous leg ulcers.
• Development of a refined ex vivo model of peritoneal adhesion formation, and a role for connexin 43 in their development.

• Thrombosis post COVID-19 vaccinations: Potential link to ACE pathways.

• Anemia prevalence in women of reproductive age in low- and middle-income countries between 2000 and 2018.
• Digital Biomarkers for Depression Screening With Wearable Devices: Cross-sectional Study With Machine Learning Modeling.
• Health, Lifestyle, and Psycho-Social Determinants of Poor Sleep Quality During the Early Phase of the COVID-19 Pandemic: A Focus on UK Older Adults Deemed Clinically Extremely Vulnerable.

• Tracking development assistance for health and for COVID-19: a review of development assistance, government, out-of-pocket, and other private spending on health for 204 countries and territories, 1990-2050.
• Global, regional, and national mortality among young people aged 10-24 years, 1950-2019: a systematic analysis for the Global Burden of Disease Study 2019.

• Impact of BMI and waist circumference on epigenome-wide DNA methylation and identification of epigenetic biomarkers in blood: an EWAS in multi-ethnic Asian individuals.

• Scaffold-Based Delivery of CRISPR/Cas9 Ribonucleoproteins for Genome Editing.

• Respiratory Mycoses in COPD and Bronchiectasis.
• Respiratory Mycoses: A Call to Action to Recognize, Educate and Invest.
• Treatment Trials in Young Patients with COPD and Pre-COPD Patients: Time to Move Forward.

• Exploring antibiotic prescribing in public and private primary care settings in Singapore: a qualitative analysis informing theory and evidence-based planning for value-driven intervention design.

• The curious case of case study research.
• Using time wisely - Aligning ice breakers with the objective of a session.

• Developmental disabilities across the world: A scientometric review from 1936 to 2020.
• Father-child dyads exhibit unique inter-subject synchronisation during co-viewing of animation video stimuli.
• Reproducible Inter-Personal Brain Coupling Measurements in Hyperscanning Settings With functional Near Infra-Red Spectroscopy.

• The trajectory of COVID-19 pandemic and handwashing adherence: findings from 14 countries.
• A Multiethnic Asian Perspective of Presumed Consent for Organ Donation: A Population-Based Perception Study.

• How doppelgänger effects in biomedical data confound machine learning.

• Amyloid Beta42 (Aβ42) Peptide Functionalized Iron Oxide Nanoparticles for Specific Targeting of SH-SY5Y Neuroblastoma Cells.
• Serotonin 1B receptor density mapping of the human brainstem using positron emission tomography and autoradiography.
• Multimedia-Based Learning Tools and Its Scope, Applications for Virtual Learning Environment.

• A Novel Mindful-Compassion Art-Based Therapy for Reducing Burnout and Promoting Resilience Among Healthcare Workers: Findings From a Waitlist Randomized Control Trial.

• Musculoskeletal regeneration: A zebrafish perspective.

• Influence of White Matter Hyperintensities on Baseline and Longitudinal Amyloid-β in Cognitively Normal Individuals.
• Altered Cerebrospinal Fluid Exosomal microRNA Levels in Young-Onset Alzheimer's Disease and Frontotemporal Dementia.

• Associations of living arrangements with symptoms and functioning in schizophrenia.
• Evaluating the utility of digital phenotyping to predict health outcomes in schizophrenia: protocol for the HOPE-S observational study.

• A Cross-Sectional Study of the Clinical Metrics of Functional Status Tools in Pediatric Critical Illness.
• Influence of red blood cell indices on HbA1c performance in detecting dysglycaemia in a Singapore preconception cohort study.
• A narrative review of skeletal muscle atrophy in critically ill children: pathogenesis and chronic sequelae.

• Intramolecular charge transfer enhancing strategy based MAO-A specific two-photon fluorescent probes for glioma cell/tissue imaging.

• The role of pulse pressure in navigating the paradigm of chronic kidney disease progression in type 2 diabetes mellitus.

• Ordered assembly of the cytosolic RNA-sensing MDA5-MAVS signaling complex via binding to unanchored K63-linked poly-ubiquitin chains.

• Pan-Sarbecovirus Neutralizing Antibodies in BNT162b2-Immunized SARS-CoV-1 Survivors.
• Differentiating coronavirus disease 2019 (COVID-19) from influenza and dengue.

• Experience and Perceptions of a Family Health History Risk Assessment Tool among Multi-Ethnic Asian Breast Cancer Patients.

• Is Virtual Team-Based Learning Feasible and Effective in Teaching Neurolocalisation?

• A global effort to dissect the human genetic basis of resistance to SARS-CoV-2 infection.

• Resistance of SARS-CoV-2 variants to neutralization by convalescent plasma from early COVID-19 outbreak in Singapore.

• Resistance of SARS-CoV-2 Delta variant to neutralization by BNT162b2-elicited antibodies in Asians.

• The role of gut dysbiosis in Parkinson's disease: mechanistic insights andtherapeutic options.

• Virtual Clinical Encounter Examination (VICEE): A novel approach for assessing medical students' non-psychomotor clinical competency.

• A Validated Instrument Measuring Students' Perceptions on Plastinated and Three-Dimensional Printed Anatomy Tools.

• PDZD-8 and TEX-2 regulate endosomal PI(4,5)P 2 homeostasis via lipid transport to promote embryogenesis in C. elegans.
• Regulation of plasma membrane sterol homeostasis by non-vesicular lipid transport.
• Patched 1 reduces the accessibility of cholesterol in the outer leaflet of membranes.

• Examining the Trends in Online Health Information-Seeking Behavior About Chronic Obstructive Pulmonary Disease in Singapore: Analysis of Data From Google Trends and the Global Burden of Disease Study.

• Cutibacterium acnes: much ado about maybe nothing much.

• What is unknown in using Microbiota as a Therapeutic?

• DDX3X loss is an adverse prognostic marker in diffuse large B-cell lymphoma and is associated with chemoresistance in aggressive non-Hodgkin lymphoma subtypes.

• Progress and Challenges in Quantifying Carbonyl-Metabolomic Phenomes with LC-MS/MS.

• Acute Isolated Near Vision Difficulty in Patients With COVID-19 Infection
• Vogt-Koyanagi-Harada Disease Associated with COVID-19 mRNA Vaccine.
• Ocular Adverse Events After COVID-19 Vaccination

• Relationship of low molecular weight fluorophore levels with clinical factors and fenofibrate effects in adults with type 2 diabetes

• Tracking development assistance for health and for COVID-19: a review of development assistance, government, out-of-pocket, and other private spending on health for 204 countries and territories, 1990-2050.

• APOC3 genetic variation, serum triglycerides, and risk of coronary artery disease in Asian Indians, Europeans, and other ethnic groups

• Respiratory Mycoses: A Call to Action to Recognize, Educate and Invest

• Accuracy of a rapid multiplex PCR plus a chromogenic phenotypic test algorithm for detection of ESBL and carbapenemase-producing Gram-negative bacilli in positive blood culture bottles

• Extracellular vesicles in cardiovascular disease

• Parental Quality of Life and Involvement in Intervention for Children or Adolescents with Autism Spectrum Disorders: A Systematic Review

• Effectiveness of a brief positive skills intervention to improve psychological adjustment in patients with end-stage kidney disease newly initiated on haemodialysis: protocol for a randomised controlled trial (HED-Start)

• Gold Nano-Urchins Enhanced Surface Plasmon Resonance (SPR) BIOSENSORS for the Detection of Estrogen Receptor Alpha (ERα) 
• Alzheimer's Disease: A Molecular View of β-Amyloid Induced Morbific Events

• A Randomized Waitlist-Controlled Trial of an Intergenerational Arts and Heritage-Based Intervention in Singapore: Project ARTISAN.

• Influence of White Matter Hyperintensities on Baseline and Longitudinal Amyloid-β in Cognitively Normal Individuals

• Comparative study of emotion recognition and theory of mind between major depressive disorder and schizophrenia

• Clinical- and omics-based models of subclinical atherosclerosis in healthy Chinese adults: a cross-sectional exploratory study.

• Lewy-body Like Inclusions in Human Midbrain Organoid Carrying Glucocerebrosidase and Alpha Synuclein Mutations 
• Activation of Autophagy Ameliorates Age-Related Neurogenesis Decline and Neurodysfunction in Adult Mice

• Global haemostatic tests demonstrate the absence of parameters of hypercoagulability in non-hypoxic mild COVID-19 patients: a prospective matched study

• The QcrB inhibitors TB47 and telacebec do not potentiate the activity of clofazimine in Mycobacterium abscessus.

• Industrially Compatible Transfusable iPSC-Derived RBCs: Progress, Challenges and Prospective Solutions

• INPP5K and Atlastin-1 maintain the nonuniform distribution of ER-plasma membrane contacts in neurons.

• A mobile swabbing booth to address Singapore GPs' concerns about swabber protection: human-centred design during the COVID-19 pandemic

• Activated natural killer cell promotes non-alcoholic steatohepatitis through mediating JAK/STAT pathway

• Timing of endoscopy for acute upper gastrointestinal bleeding: a territory-wide cohort study

• Bioinspired short peptide hydrogel for versatile encapsulation and controlled release of growth factor therapeutics

• Factors affecting duration of SARS-Cov-2 viral shedding in mildly symptomatic patients isolated in a community facility

• Itaconic acid exerts anti-inflammatory and antibacterial effects via promoting pentose phosphate pathway to produce ROS

• GALAXY Workflow for Bacterial Next-Generation Sequencing De Novo Assembly and Annotation
• Trapping and Detection of Single Viruses in an Optofluidic Chip

• The International Globe And Adnexal Trauma Epidemiology Study Igates. Global Current Practice Patterns for the Management of Open Globe Injuries

• Enhanced postoperative surveillance versus standard of care to reduce mortality among adult surgical patients in Africa (ASOS-2): a cluster-randomised controlled trial.
• Sucrose Esters: Potent and Selective Inhibitors of α-glucosidase and α-amylase

• Risk for short-term undesirable outcomes in older emergency department users: Results of the ER2 observational cohort study

• Cx43 mediates changes in myofibroblast contraction and collagen release in human amniotic membrane defects after trauma

• Global, regional, and national progress towards Sustainable Development Goal 3.2 for neonatal and child health: all-cause and cause-specific mortality findings from the Global Burden of Disease Study 2019
• Identifying topics for future Cochrane Public Health reviews

• HIGH FREQUENCY OF ALLERGIC BRONCHOPULMONARY ASPERGILLOSIS IN BRONCHIECTASIS-COPD OVERLAP
• Aspergillus-Associated Endophenotypes in Bronchiectasis

• Does performance at medical school predict success at the Intercollegiate Membership of the Royal College of Surgeons (MRCS) examination? A retrospective cohort study

• OXTR moderates adverse childhood experiences on depressive symptoms among incarcerated males
• Influences of Social Distancing and attachment styles on the strength of the Halo Effect.
• Father-child dyads exhibit unique inter-subject synchronisation during co-viewing of animation video stimuli

• Disrupting the LINC complex by AAV mediated gene transduction prevents progression of Lamin induced cardiomyopathy
• Mn 2+ -Phos-Tag Polyacrylamide for the Quantification of Protein Phosphorylation Levels

• Polygenic Risk Scores in a Prospective Parkinson's Disease Cohort.

• Cancer caregivers unmet needs and emotional states across cancer treatment phases

• The Effect of Therapeutic Alliance on Attitudes Toward Psychiatric Medications in Schizophrenia

• Insights into the structure and RNA-binding specificity of Caenorhabditis elegans Dicer-related helicase 3 (DRH-3).

• Remdesivir for the prevention of invasive mechanical ventilation or death in COVID-19 - A post-hoc analysis of the Adaptive COVID-19 Treatment Trial-1 Cohort Data
• Contemporary narrative review of treatment options for COVID-19
• A vaccination update for rheumatologists-SARS-CoV-2, influenza and herpes zoster
• Meropenem Versus Piperacillin-Tazobactam for Definitive Treatment of Bloodstream Infections Caused by AmpC β-Lactamase-Producing Enterobacter spp, Citrobacter freundii, Morganella morganii, Providencia spp, or Serratia marcescens: A Pilot Multicenter Randomized Controlled Trial (MERINO-2)

• Clinical and virological features of SARS-CoV-2 variants of concern: a retrospective cohort study comparing B.1.1.7 (Alpha), B.1.315 (Beta), and B.1.617.2 (Delta)

• Nosocomial infections among COVID-19 patients: an analysis of intensive care unit surveillance data

• DNA methylation and breast cancer-associated variants

• Irritable bowel syndrome and risk of glaucoma: An analysis of two independent population-based cohort studies

• Investigating the effectiveness of three-dimensional printed anatomical models compared to plastinated human specimens in learning cardiac and neck anatomy: A randomized cross-over study
• Exploring the feasibility of using very short answer questions (VSAQs) in team-based learning (TBL).

• Promotion of knowledge transfer and retention in year 2 medical students using an online training exercise

• X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19
• Autoantibodies neutralizing type I IFNs are present in ~ 4% of uninfected individuals over 70 years old and account for ~ 20% of COVID-19 deaths
• Children with Plasmodium vivax infection previously observed in Namibia, were Duffy negative and carried a c.136G > A mutation

• Mechanisms of weight loss after obesity surgery
• Intravital imaging of islet Ca 2+ dynamics reveals enhanced β cell connectivity after bariatric surgery in mice.
• Distinct Molecular Signatures of Clinical Clusters in People with Type 2 Diabetes: an IMIRHAPSODY Study.

• GRAMD1-mediated accessible cholesterol sensing and transport.

• Circulating microRNA Breast Cancer Biomarker Detection in Patient Sera with Surface Plasmon Resonance Imaging Biosensor

• GDF15 mediates the metabolic effects of PPARβ/δ by activating AMPK
• The PPARβ/δ-AMPK Connection in the Treatment of Insulin Resistance

• BD metabonomics predicts phenotype, disease course, and treatment response
• Understanding Choline Bioavailability and Utilization: First Step Toward Personalizing Choline Nutrition

• Tracking oxidation-induced alterations in fibrin clot formation by NMR-based methods

• Pan-Sarbecovirus Neutralizing Antibodies in BNT162b2-Immunized SARS-CoV-1 Survivors

• The United States Eye Injury Registry: past and future directions (Ophthalmology)
• Antiviral Therapy for Varicella Zoster Virus (VZV) and Herpes Simplex Virus (HSV)-Induced Anterior Uveitis: A Systematic Review and Meta-Analysis

• Experiences, opinions and expectations of health care providers towards an intensive care unit follow-up clinic: Qualitative study and online survey

• Feruloyl Sucrose Esters: POTENT AND SELECTIVE INHIBITORS OF α-GLUCOSIDASE AND α-AMYLASE
• Effectiveness of data auditing as a tool to reinforce good research data management (RDM) practice: a Singapore study

• Higher extracellular water to total body water ratio was associated with chronic kidney disease progression in type 2 diabetes. 2021

• Resident macrophages restrain pathological adipose tissue remodeling and protect vascular integrity in obese mice

• Dysfunction of the key ferroptosis-surveilling systems hypersensitizes mice to tubular necrosis during acute kidney injury

• Just-in-time Adaptive Mechanisms of Popular Mobile Applications for Individuals with Depression: Systematic Review
• Choice of Behavioral Change Techniques in Health Care Conversational Agents: Protocol for a Scoping Review

• Health literacy and health outcomes in patients with low back pain: a scoping review

• Evaluating the impact of COVID-19 on the adoption of virtual care in general practice in 20 countries (inSIGHT): rationale and study protocol.

• Self-guided Cognitive Behavioral Therapy Apps for Depression: Systematic Assessment of Features, Functionality, and Congruence With Evidence

• Digital Health Training Programs for Medical Students: Scoping Review.

• Intranasal octenidine for methicillin-resistant Staphylococcus aureus (MRSA) carriers and universal octenidine bathing reduced MRSA acquisition in an acute-care general ward.

• Short-term mortality from HIV-infected persons diagnosed from 2012 to 2016: Impact of late diagnosis of HIV infection

• When I say … privilege. 2021. Medical Education.
• Opening up the black box of a Gateway to Medicine programme: a realist evaluation

• Psychometric properties of the thyroid-specific quality of life questionnaire ThyPRO in Singaporean patients with Graves' disease

• Parental involvement in developmental disabilities across cultures. 2021. Research in Developmental Disabilities

• Modulation of Instagram Number of Followings by Avoidance in Close Relationships in Young Adults under a Gene x Environment Perspective

• Effectiveness and acceptability of a multidisciplinary approach in improving the care of patients with advanced chronic kidney disease: a pilot study

• Leucine-Rich α-2-Glycoprotein 1 Suppresses Endothelial Cell Activation Through ADAM10-Mediated Shedding of TNF-α Receptor.
• FUT6 deficiency compromises basophil function by selectively abrogating their sialyl-Lewis x expression.

• Discontinuation Rate of Newly Prescribed Donepezil in Alzheimer's Disease Patients in Asia

• Association of Structural Magnetic Resonance Imaging Measures With Psychosis Onset in Individuals at Clinical High Risk for Developing Psychosis: An ENIGMA Working Group Mega-analysis

• Glycemic Index, Glycemic Load, and Cardiovascular Disease and Mortality

• Lewy-body Like Inclusions in Human Midbrain Organoid Carrying Glucocerebrosidase and Alpha Synuclein Mutations

• Amidoxime prodrugs convert to potent cell-active multimodal inhibitors of the dengue virus protease

• Variation in the risk of colorectal cancer in families with Lynch syndrome: a retrospective cohort study.

• How practice setting affects family physicians' views on genetic screening: a qualitative study

• Tryptophan-metabolizing gut microbes regulate adult neurogenesis via the aryl hydrocarbon receptor.

• Plasmodium vivax binds host CD98hc (SLC3A2) to enter immature red blood cells
• Rodent Malaria Erythrocyte Preference Assessment by an Ex Vivo Tropism Assay

• Community case managers' challenges collaborating with primary care when managing complex patients in the community: A qualitative study in Singapore

• Acute gastrointestinal bleeding: proposed study outcomes for new randomised controlled trials. 2021. Alimentary Pharmacology & Therapeutics
• Clopidogrel is no better or worse than aspirin when combined with proton pump inhibitors in the prevention of major adverse event. Is the jury out?

• A PDZ Protein GIPC3 Positively Modulates Hedgehog Signaling and Melanoma Growth. 2021. Journal of Investigative Dermatology

• Mass spectrometry-based metabolomics: a guide for annotation, quantification and best reporting practices
• Repurposed floxacins targeting RSK4 prevent chemoresistance and metastasis in lung and bladder cancer.

• Single Cell Metabolite Detection Using Inertial Microfluidics-Assisted Ion Mobility Mass Spectrometry

• Draft Genome Sequence of Enterobacter hormaechei subsp. steigerwaltii Strain BEI01

• Frequency of hand eczema in the elderly - cross-sectional findings from the German AugUR study

• Quality of life in atopic dermatitis in Asian countries: a systematic review

• A neural circuit for excessive feeding driven by environmental context in mice.

• Emergency room evaluation and recommendations for older emergency department users: results of the ER 2 experimental study

• Protocol of the Cognitive Health in Ageing Register: Investigational, Observational and Trial Studies in Dementia Research (CHARIOT): Prospective Readiness cOhort (PRO) SubStudy

• Matriptase activation of Gq drives epithelial disruption and inflammation via RSK and DUOX.

• Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes

• Similarity network fusion (SNF) for the integration of multi-omics and microbiomes in respiratory disease
• Inactivation of common airborne antigens by perfluoroalkyl chemicals modulates early life allergic asthma

• Remediation programmes for practising doctors to restore patient safety: the RESTORE realist review
• The visual vernacular: embracing photographs in research
• Author's reply. 2021. Journal of the Royal College of Physicians of Edinburgh.
• Putting spin on the great gamble

• OXTR moderates adverse childhood experiences on depressive symptoms among incarcerated males
• Savouring as an Intervention to Decrease Negative Affect in Anxious Mothers of Children with Autism and Neurotypical Children
• An fNIRS Investigation of Masculinity, Femininity, and Sex on Nonparents' Empathic Response to Infant Cries

• Novel Optineurin Frameshift Insertion in a Family With Frontotemporal Dementia and Parkinsonism Without Amyotrophic Lateral Sclerosis

• Nanotechnology Facilitated Cultured Neuronal Network and Its Applications

• "I decide myself"- A qualitative exploration of end of life decision making processes of patients and caregivers through Advance Care Planning

• Discontinuation Rate of Newly Prescribed Donepezil in Alzheimer's Disease Patients in Asia

• Genome wide study of tardive dyskinesia in schizophrenia.
• Large-scale evaluation of the Positive and Negative Syndrome Scale (PANSS) symptom architecture in schizophrenia

• Hippocampal transcriptome profiling reveals common disease pathways in chronic hypoperfusion and aging

• The trans-ancestral genomic architecture of glycemic traits
• Data resource profile: Understanding the patterns and determinants of health in South Asians-the South Asia Biobank

• Molecular Insights into the Flavivirus Replication Complex

• An observational study of the prevalence of metabolic syndrome in treatment-experienced people living with HIV in Singapore.

• The Skin in Cowden Syndrome

• Systemic Perturbations in Amine and Kynurenine Metabolism Associated with Acute SARS-CoV-2 Infection and Inflammatory Cytokine Responses

• Meningeal inflammation in multiple sclerosis induces phenotypic changes in cortical microglia that differentially associate with neurodegeneration
• Investigation of the correlation between mildly deleterious mtDNA Variations and the clinical progression of multiple sclerosis.

• Virtual Clinical Encounter Examination (VICEE): A novel approach for assessing medical students' non-psychomotor clinical competency

• Replication and cross-validation of type 2 diabetes subtypes based on clinical variables: an IMI-RHAPSODY study
• Evaluation of efficacy- versus affinity-driven agonism with biased GLP-1R ligands P5 and exendin-F1

• Differential Household Attack Rates Mirror the Ability to Control Coronavirus Disease 2019 (COVID-19)

• A Virus-Specific Immune Rheostat in the Immunome of Patients Recovering From Mild COVID-19

• Persistent Symptoms and Association With Inflammatory Cytokine Signatures in Recovered Coronavirus Disease 2019 Patients

• Author Correction: Increased Serum Hyaluronic Acid and Heparan Sulfate in Dengue Fever: Association with Plasma Leakage and Disease Severity

• Changing the Cortical Conductor's Tempo: Neuromodulation of the Claustrum

• Alzheimer's disease research progress in Australia: The Alzheimer's Association International Conference Satellite Symposium in Sydney

• A flexible multiplexed immunosensor for point-of-care in situ wound monitoring

• The Eye as a Transplantation Site to Monitor Pancreatic Islet Cell Plasticity

• Virtual reality in medical students' education: a scoping review protocol

• Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990-2019: a systematic analysis from the Global Burden of Disease Study 2019
• Perceived facilitators and barriers to chronic disease management in primary care networks of Singapore: a qualitative study

• Structures of wild-type and H451N mutant human lymphocyte potassium channel K V 1.3.

• Maintaining engagement with efficiency: Facilitating large-group online TBL

• Salt for Patients with Heart Failure and Hyponatremia?
• Sex Modifies the Association of Fibroblast Growth Factor 21 With Subclinical Carotid Atherosclerosis.

• The Moderating Role of Parental Sleep Knowledge on Children with Developmental Disabilities and Their Parents' Sleep
• The Recognition of Cross-Cultural Emotional Faces Is Affected by Intensity and Ethnicity in a Japanese Sample

• Trans-Ethnic Fine-Mapping of the Major Histocompatibility Complex Region Linked to Parkinson's Disease

• A 3D Fiber-Hydrogel Based Non-Viral Gene Delivery Platform Reveals that microRNAs Promote Axon Regeneration and Enhance Functional Recovery Following Spinal Cord Injury

• Recalled Parental Bonding Interacts with Oxytocin Receptor Gene Polymorphism in Modulating Anxiety and Avoidance in Adult Relationships

• Targeted Lipidomics of Drosophila melanogaster During Development

• An In Vivo Study of a Rat Fluid-Percussion-Induced Traumatic Brain Injury Model with [ 11 C]PBR28 and [ 18 F]flumazenil PET Imaging

• Direct isolation of circulating extracellular vesicles from blood for vascular risk profiling in type 2 diabetes mellitus
• A novel human arterial wall-on-a-chip to study endothelial inflammation and vascular smooth muscle cell migration in early atherosclerosis.

• Baseline Neurodegeneration Influences the Longitudinal Effects of Tau on Cognition
• The Association Between Diabetes Mellitus and Mild Behavioral Impairment Among Mild Cognitive Impairment: Findings from Singapore

• Association of Structural Magnetic Resonance Imaging Measures With Psychosis Onset in Individuals at Clinical High Risk for Developing Psychosis: An ENIGMA Working Group Mega-analysis
• Defining negative symptoms remission in schizophrenia using the Brief Negative Symptom Scale

• Plasma Branched-Chain Amino Acids Are Associated With Greater Fasting and Postprandial Insulin Secretion in Non-diabetic Chinese Adults
• Diffusely increased 18 F-FDG thyroid radionuclide uptake is not always hyperthyroidism

• Association of metabolic-bariatric surgery with long-term survival in adults with and without diabetes: a one-stage meta-analysis of matched cohort and prospective controlled studies with 174 772 participants

• 2-Cyanoisonicotinamide Conjugation: A Facile Approach to Generate Potent Peptide Inhibitors of the Zika Virus Protease.

• Management of individuals with germline variants in PALB2: a clinical practice resource of the American College of Medical Genetics and Genomics (ACMG)
• Telomere biology disorders
• Homologous recombination deficiency: cancer predispositions and treatment implications
• Understanding patients' views and willingness toward the use of telehealth in a cancer genetics service in Asia. 2021. Journal of Genetic Counseling.

• Regional Diets Targeting Gut Microbial Dynamics to Support Prolonged Healthspan

• Dysregulation of the Pdx1/Ovol2/Zeb2 axis in dedifferentiated β-cells triggers the induction of genes associated with epithelial-mesenchymal transition in diabetes

• The Effect of Orally Administered Low-Dose Dronabinol on Retinal Blood Flow and Oxygen Metabolism in Healthy Subjects

• An Overview of Commercially Available Apps in the Initial Months of the COVID-19 Pandemic. 2021
• Vaccine acceptability, uptake and completion amongst men who have sex with men: A systematic review, meta-analysis and theoretical framework
• Correction to: Medical students' attitudes towards careers in primary care in Singapore

• Teledermatology in Primary Care in Singapore: Experiences of Family Doctors and Specialists

• Cutibacterium acnes: much ado about maybe nothing much.

• Mapping ethico-legal principles for the use of artificial intelligence in gastroenterology

• PPARs and Tumor Microenvironment: The Emerging Roles of the Metabolic Master Regulators in Tumor Stromal-Epithelial Crosstalk and Carcinogenesis

• Core-Shell Structured Antimicrobial Nanofiber Dressings Containing Herbal Extract and Antibiotics Combination for the Prevention of Biofilms and Promotion of Cutaneous Wound Healing

• Asymptomatic COVID-19: disease tolerance with efficient anti-viral immunity against SARS-CoV-2

• Epidemiology and Transmission Of Carbapenemase-Producing Enterobacteriaceae in a Healthcare Network of an Acute Hospital and Its Affiliated Intermediate- and Long-Term Care Facilities in Singapore

• Re: Chen et al.: The United States Eye Injury Registry: past and future directions (Ophthalmology. 2021;128:647-648)
• Perinatal risk factors associated with central retinal changes in former preterm children on optical coherence tomography angiography
• Clinical and Multimodal Imaging Clues in Differentiating Between Tuberculomas and Sarcoid Choroidal Granulomas
• Conjunctival Findings in Patients With Coronavirus Disease 2019
• Zika Virus and Anterior Uveitis-4 Years After the Pandemic

• Changing the cortical conductor’s tempo: Neuromodulation of the claustrum

• Publisher Correction: Pre-symptomatic Caspase-1 inhibitor delays cognitive decline in a mouse model of Alzheimer disease and aging

• Long-term effectiveness of mHealth physical activity interventions: a systematic review and meta-analysis of randomized-controlled trials

• Are digital technologies fit for clinical purposes? A systematic review and qualitative synthesis of information quality frameworks for digital healthcare

• Exercise testing in patients with aortic stenosis: clinically useful

• DNA-derived nanostructures selectively capture gram-positive bacteria

• Regulatory Light Chains in Cardiac Development and Disease
• Post COVID-19 Arterial Thromboembolism: A Clear and Present Danger

• Update in COVID-19
• Integrative microbiomics in bronchiectasis exacerbations

• Determinants of antibiotic over-prescribing for upper respiratory tract infections in an emergency department with good primary care access: a quantitative analysis

• Redefining scholarship for health professions education: AMEE Guide No. 142
• The curious case of case study research
• iViewExpert: A tool to uncover expertise and support surgical skills training
• Simulation for technical skill acquisition in open vascular surgery

• Monocyte progenitors give rise to multinucleated giant cells

• Amyloid Beta42 (Aβ42) Peptide Functionalized Iron Oxide Nanoparticles for Specific Targeting of SH-SY5Y Neuroblastoma Cells

• Food for Life and Palliation (FLiP)': a qualitative study for understanding and empowering dignity and identity for terminally ill patients in Asia

• A Cross-Sectional Study of the Clinical Metrics of Functional Status Tools in Pediatric Critical Illness
• Skeletal Muscle Changes, Function, and Health-Related Quality of Life in Survivors of Pediatric Critical Illness

• Higher extracellular water to total body water ratio was associated with chronic kidney disease progression in type 2 diabetes

• Stool metagenome analysis of patients with Klebsiella pneumoniae liver abscess and their domestic partners
• Lack of detail in population-level data impedes analysis of SARS-CoV-2 variants of concern and clinical outcomes
• Author Correction: The higher prevalence of extended spectrum beta-lactamases among Escherichia coli ST131 in Southeast Asia is driven by expansion of a single, locally prevalent subclone
• Association of SARS-CoV-2 clades with clinical, inflammatory and virologic outcomes: An observational study
• Predictors for development of critical illness amongst older adults with COVID-19: Beyond age to age-associated factors

• Evaluation of treatment effects in patients with endometrial cancer and POLE mutations: An individual patient data meta-analysis

• Plasma neurofilament light chain levels predict improvement in late phase after stroke

• Mixed-charge pseudo-zwitterionic copolymer brush as broad spectrum antibiofilm coating

• Surface-in pathology in multiple sclerosis: a new view on pathogenesis?

• The role of gut dysbiosis in Parkinson's disease: mechanistic insights and therapeutic options

• Cytomegalovirus infection is associated with an increase in aortic stiffness in older men which may be mediated in part by CD4 memory T-cells

• A selective HDAC8 inhibitor potentiates antitumor immunity and efficacy of immune checkpoint blockade in hepatocellular carcinoma

• Kinomic profile in patient-derived glioma cells during hypoxia reveals c-MET-PI3K dependency for adaptation

• The pregnane X receptor drives sexually dimorphic hepatic changes in lipid and xenobiotic metabolism in response to gut microbiota in mice
• Invalidation of the Transcriptional Modulator of Lipid Metabolism PPARβ/δ in T Cells Prevents Age-Related Alteration of Body Composition and Loss of Endurance Capacity
• Integrative study of diet-induced mouse models of NAFLD identifies PPARα as a sexually dimorphic drug target

• Metabolomics Signatures of Aging: Recent Advances

• Personalised randomised controlled trial designs-a new paradigm to define optimal treatments for carbapenem-resistant infections

• Clinical features and predictors of severity in COVID-19 patients with critical illness in Singapore

George AUGUSTINE
Synapsins and the Synaptic Vesicle Reserve Pool: Floats or Anchors?.

Anna BARRON
Neuroprotective effect of mitochondrial translocator protein ligand in a mouse model of tauopathy.
Mitochondrial Regulation of Microglial Immunometabolism in Alzheimer's Disease.

Olivier BEAUCHET
Motoric cognitive risk syndrome: what's new?.
Pre-Dementia Stages and Incident Dementia in the NuAge Study.

David BECKER
Epidermal graft encourages wound healing by down-regulation of gap junctional protein and activation of wound bed without graft integration as opposed to split-thickness skin graft.
Pulpal upregulation of connexin 43 during pulpitis.
Characterisation of an ischemia reperfusion model for the formation of a stage I pressure ulcer in mouse skin.

David BECKER / TEY Hong Liang
Changes in connexin 43 in inflammatory skin disorders: Eczema, psoriasis, and Steven-Johnson syndrome/toxic epidermal necrolysis.

Per-Olof BERGGREN
Lowering apolipoprotein CIII protects against high-fat diet-induced metabolic derangements.

James BEST
School-based integrated healthcare model: how Our Mia Mia is improving health and education outcomes for children and young people.

Josip CAR
A Comparative Study of International and Asian Criteria for Overweight or Obesity at Workplaces in Singapore.

John CHAMBERS
Publisher Correction: Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals.
Low uptake of COVID-19 prevention behaviours and high socioeconomic impact of lockdown measures in South Asia: Evidence from a large-scale multi-country surveillance programme.

Angela CHOW
Healthcare workers as "canaries" for acute respiratory infections and pathogens during the COVID-19 pandemic.
The "Timeless" use of Influenza-like Illness Criteria for influenza Detection in the Tropics.
Epidemiological factors associated with recent HIV infection among newly-diagnosed cases in Singapore, 2013-2017.

Christine CHEUNG/ David LYE / Laurent RENIA
Convalescent COVID-19 patients are susceptible to endothelial dysfunction due to persistent immune activation.

Sanjay CHOTIRMALL
Pseudomonas aeruginosa in bronchiectasis: infection, inflammation and therapies.
Respiratory Mycoses in COPD and Bronchiectasis.
Mycopathologia 2020: Legacy and Change to Remain Relevant for Content, Creation, and Communication.

Jennifer CLELAND
Optimising the delivery of remediation programmes for doctors: a realist review.
Performance at medical school selection correlates with success in Part A of the intercollegiate Membership of the Royal College of Surgeons (MRCS) examination.

Jennifer CLELAND / Lucy ROSBY
Cameras on or off: What is the question?.

Norris Ray DUNN
An NKX2-1 GFP and TP63 tdTomato dual fluorescent reporter for the investigation of human lung basal cell biology.

Gianluca ESPOSITO
An Analysis of the Generalizability and Stability of the Halo Effect During the COVID-19 Pandemic Outbreak.
A Scientometric Approach to Review the Role of the Medial Preoptic Area (MPOA) in Parental Behavior.
Deep Neural Networks and Transfer Learning on a Multivariate Physiological Signal Dataset.

FOO Jia Nee
Identification of a Novel Homozygous Missense (c.443A>T:p.N148I) Mutation in BBS2 in a Kashmiri Family with Bardet-Biedl Syndrome.

GUAN Xue Li
Combination With Tomatidine Improves the Potency of Posaconazole Against Trypanosoma cruzi.

Andy HO
Psychological resilience among palliative patients with advanced cancer: A systematic review of definitions and associated factors.

Andy HO / Olivier BEAUCHET
Long-term effects of the Montreal museum of fine arts participatory activities on frailty in older community dwellers: results of the A-Health study.

Balazs GULYAS
Auditory steady-state responses during and after a stimulus: Cortical sources, and the influence of attention and musicality.

HOU Han Wei
Direct and Label-Free Cell Status Monitoring of Spheroids and Microcarriers Using Microfluidic Impedance Cytometry.

Nagaendran KANDIAH
The Efficacy of Transdermal Rivastigmine in Mild to Moderate Alzheimer's Disease with Concomitant Small Vessel Cerebrovascular Disease: Findings from an Open-Label Study.

Jimmy LEE
Association Between Cardiovascular Risk Factors and Cognitive Impairment in People With Schizophrenia: A Systematic Review and Meta-analysis.
HOPES: An Integrative Digital Phenotyping Platform for Data Collection, Monitoring, and M.achine Learning
Predicting Real-World Functioning in Schizophrenia: The Relative Contributions of Neurocognition, Functional Capacity, and Negative Symptoms.

Melvin LEOW
Dissociation Between Insulin Resistance and Abnormalities in Lipoprotein Particle Concentrations and Sizes in Normal-Weight Chinese Adults.
Aging-induced isoDGR-modified fibronectin activates monocytic and endothelial cells to promote atherosclerosis.

LIM Kah Leong
Loss of FEZ1, a gene deleted in Jacobsen syndrome, causes locomotion defects and early mortality by impairing motor neuron development.

Fabian LIM
Low muscle mass is associated with progression of chronic kidney disease and albuminuria - An 8-year longitudinal study in Asians with Type 2 Diabetes.

LUO Dahai
Structural insights into viral RNA capping and plasma membrane targeting by Chikungunya virus nonstructural protein 1.

David LYE
Risk Factors for Development of Acute Kidney Injury in COVID-19 Patients: A Retrospective Observational Cohort Study.
Dynamics of SARS-CoV-2 neutralising antibody responses and duration of immunity: a longitudinal study.
Highly functional virus-specific cellular immune response in asymptomatic SARS-CoV-2 infection.

Joanne NGEOW
DNA methylation and breast cancer-associated variants.
CDKN2A germline alterations and the relevance of genotype-phenotype associations in cancer predisposition.
Clinical implementation of an oncology-specific family health history risk assessment tool.

Michael NILSSON
More than motor impairment: A spatiotemporal analysis of cognitive impairment and associated neuropathological changes following cortical photothrombotic stroke.

Kevin PETHE
HflX is a GTPase that controls hypoxia-induced replication arrest in slow-growing mycobacteria.