Ph.D. & M.Sc. Projects

The application deadline for Ph.D. projects is as follows:
 
August intake: 31 January
January intake: 31 July
 
Apply online via NTU website here.
 
Email your application ID to ac-sbs-gs@ntu.edu.sg, so that we can facilitate the application process.
 
If you have any queries, please write to ac-sbs-gs@ntu.edu.sg
 

The following table lists the Ph.D. projects that are currently available. 

Click on the individual links to find out more about each research project. You may contact the research supervisor directly if you have any questions regarding the project you are interested in. 
SupervisorResearch Project Title
Bhattacharyya, Suraji​​tDesign and mode of action of antimicrobials (peptides and mimetics) and mechanisms of bacterial resistance
Designing Functional Mini-proteins
Mechanisms of Integrins Mediated Cell-Cell Adhesion & Therapeutics Development​
Basak, SandipUnderstanding the molecular mechanism of odorant receptor co-receptor (orco) in Anopheles gambiae
Ch’ng, Toh Hean*​Neurobiology of Learning and Memory
Synapse-to-nucleus signaling and transcription-dependent plasticity in neurodegenerative disorders
The role of astrocytes during learning and memory​
​Choe, Young-JunQuality control mechanisms of incomplete nascent proteins
Pathogenic mechanisms in ALS  (or Lou Gehrig's disease)
Roca, Francesc Xavier Splicing mechanisms and their alterations in human genetic diseases
Fullwood, MelissaUnderstanding 3D genome organization in cancer through an integrated artificial intelligence and molecular biology approach​
Gao, YongguiStructure and function of ribosome and drug design; Glycobiology towards Biofuel; Pathogen virulence
​Goh, WilsonMissing protein prediction using networks​
Development of AIs for predicting medical usage of novel plants based on genomic, proteomic and metabolite profiles
Advanced predictive models based on metabonomic profiling
Biomarker prediction of cancer based on big data and network analytics
Gruber, GerhardIdentifying novel compound targets through understanding the Mycobacterial stringent response to stress
Kline, KimberlyFormation and function of membrane lipid microdomains in Enterococcus faecalis​
Mechanisms of E. faecalis Subversion of Neutrophil-mediated killing​
Mechanisms of E. faecalis Immune Modulation in Macrophages​
The lipidomics of Enterococcus faecalis infection
Koh, Cheng GeeCancer Microenvironment and its Impact on the Biology of Cancer Cells​
Functional Relationship between Actin Cytoskeleton Regulation and Cell Cycle Progression 
Regulation of embryonic stem cell pluripotency and differentiation by biochemical and biophysical cues
Lescar, JulienThe L protein from the Respiratory Syncytial Virus: Structures and functions
Liang, Zhao-Xun ​Genome-guided discovery of marine natural products
Production of cannabinoids and other natural products using microbial hosts 
Li, Hoi Yeung ​Application of 3D culture to investigate somatic cells reprogramming, cancer development and various cellular events​
Investigation on the molecular mechanism and physiological roles of AAA-ATpase p97/VCP in cancer metastasis
​Multidisciplinary approach to redefine chromosome condensation models
Li, YinghuiCharacterizing the regulatory landscape of cancer drivers and vulnerabilities
Epigenetic regulation of NF-κB in cancers
Role of MAPK signaling in chromatin organization and transcriptional control of cancers
Lin, ValerieDiscovery of biomarkers predictive of endometrial receptivity
Elucidation of caspase-independent cell death pathways in cancer
Lu, LanyuanInvestigating the protein phase behavior in polarized fungal growth by coarse-grained molecular simulation​
Lu, LeiHow proteins are targeted to cilia
The dynamic trafficking within the Golgi
The effect of nutrient on the membrane trafficking
​Ludwig, Alexander ​ ​​Functional characterization of the Crumbs polarity complex during lumenogenesis in 3D epithelial cell cultures and during zebrafish kidney development
​Ma, Wei​Functional characterization of transcriptional regulator(s) in plant oil biosynthesis and plant development​
Miao, YansongCellular Aging by Biomolecular Phase-separation
Rewiring Plant-pathogen Interactions for Novel Agrifood Technology
Liquid-liquid Phase Separation (LLPS)-regulated plant immunity
Phase Separation-mediated filamentous fungal growth and host invasion
Mitra, RupshiIndividual difference in stress coping: A possible brain mechanism
Stress manifestation and its implications in primate society
Mu, Yuguang​ ​Improved computational models for peptide/HLA interactions with T cells and natural killer cells
​Improve protein-ligands docking scoring using machine learning method.
Understanding off-target effects of CRISPR/Cas9 using molecular dynamics simulations​
Mueller-Cajar, OliverMechanistic studies concerning biological CO2 fixation
Microalgal CO2 superchargers
Mutwil, MarekElucidating adaptive mechanism conferring resilience to environmental stress in plants
Identifying biosynthetic pathways for high-value compounds
LEO – Life Expression Omnibus
Identification of metabolic master regulators
Unravelling metabolic pathways of Singapore flora
Pervushin, KonstantinStructural variation and inhibition of key coronaviral ion channels in SARS-CoV-2
Artificial Intelligence-based advisory system for blood sugar management in elderly diabetics
Structural basis of amyloid seeds disaggregation by neuroprotective chaperones as a novel therapeutic avenue in TGFBIp-related cornea
​​Preiser, Peter​ ​ ​ ​Small variant antigens of malaria parasites as key regulators of biological functions
The plasmodium parasite exported protein interactome inside the host erythrocyte
​The role of RNA modifications in malaria parasite biology​
Investigating the role of camp signalling conservation during malaria parasite invasion
Discovering new target space for the development of drugs against malaria parasites
Ruedl, ChristianeCross-talk between resident macrophages and adipose tissue in obesity: searching for culprits
Salojärvi, ​Jarkko​Adaptive radiation following the loss of a root symbiont​
Bhushan, Shashi Structural and biochemical studies of Mycobacterial biosynthetic enzymes
Structural and biochemical studies of Mycobacterial drug transporters 
Structural analysis of drug binding on Potassium Channels
Su, I-HsinFunctional characterization and physiological significance of SETD3-mediated methylation in immune responses
Molecular and functional characterization of UBR7-regulated cell adhesion and migration
The role of cytoplasmic EZH2 in cancer stem cells 
​​The role of dendritic cells in T cell development and thymic involution
Surgrue, RichardDevelopment of a vaccine candidate for EMCV
Evaluation of 3D cell culture systems for use as bioreactors in production for vaccine development and isolation of viruses from clinical specimens
Host pathogen interactions with the influenza virus polymerase complex​
Signalling pathways that mediate respiratory syncytial virus morphogenesis 
Sze, Siu Kwan NewmanElucidating epigenetic regulation in food/diet induced obesity and metabolic syndrome
Hypoxia-sensitive epigenetic regulators (HYSERs) as novel targets for the treatment of solid tumors
Pre-clinical development of a cancer immunotherapy targeting tumor exosomal proteins
Translational biomarker research for prediction of diabetic vascular complications in diabetes mellitus patients
​​ Translational biomarker research to identify silent vulnerable patient at risk of major adverse cardiovascular events​ ​​
Tan, Suet MienInvestigating integrin-linked cell adhesion-mediated drug resistance in leukemic cells
Investigating the roles of kindlins in cancer epithelial-mesenchymal transition
Tashiro, AyumuElectrophysiological investigation of the function of new neurons in adult hippocampus
Molecular mechanisms underlying experience- and activity-dependent regulations of adult neurogenesis
Roles of astrocyte-neuron signaling in neuronal information processing in the hippocampus
Thanabalu, ThirumaranMolecular characterization of Cancer resistance in Atopic Dermatitis mice (Skin Research Scholarship)
Identification of the molecular mechanism of long hair phenotype in triple transgenic mice (Skin Research Scholarship)
Role of N-WASP in Squamous Cell Carcinoma (Skin Research Scholarship)​
Thibault, GuillaumeCellular Stress Response in Metabolic Syndrome
The role of the endoplasmic reticulum in age-related macular degeneration (AMD)
Dissecting synergetic outcome of host-microbe interactions in wound of diabetic animal models
Torres, JaumesStructural features and potential for inhibition of channel activity in coronavirus envelope proteins
Vyas, AjaiBehavioral manipulation of the host by the parasites
Non-consumptive effects of predation
Wu BinComprehending the molecular dynamics of CARD domain driven Nuclear Speckles – a 'nuclear' approach to understand autoimmune diseases.
​​​​​* PhD projects not available for Research Student Scholarships from SBS-NTU​
The application deadline for M.Sc. projects is as follows:
 
August intake: 31 January
January intake: 31 July
 
Apply online via NTU website here.
 
Email your application ID to ac-sbs-gs@ntu.edu.sg, so that we can facilitate the application process.
 
If you have any queries, please write to ac-sbs-gs@ntu.edu.sg
 

The following table lists the M.Sc. projects that are currently available. 

Click on the individual links to find out more about each research project. You may contact the research supervisor directly if you have any questions regarding the project you are interested in. 
 Supervisor Research Project Title
Fullwood, MelissaMachine Learning of Chromatin Interactions and Transcription in Cancer
Investigating the effects of DNA hypomethylating agents on 3D genome organization in myeloid leukemia
Gao, Yonggui
Molecular analysis of proteins in ribosome biogenesis
Data mining for genes involving exopolysaccharide biosynthesis
Goh, WilsonDevelopment of data science techniques for predicting natural compound medicinal indications​
Integrating knowledge with artificial intelligence for natural product drug discovery
Development of AIs for predicting medical usage of novel plants based on genomic, proteomic and metabolite profiles
Developing novel AI features for predicting mental health status from audio visual cues
Large-scale analysis of schizophrenia blood-based signatures
Grüber, Gerhard Understanding the Mycobacterium abscessus energy converter F-ATP synthase to discover novel compound targets
Hong, YanVolatile based diagnosis for pathogenic fungi
​Li, YinghuiExpression Quantitative Trait Loci (eQTLs) prediction optimisation and multi-data integration with machine learning to target novel cis-regulatory relationships in cancer 
Characterizing the regulatory landscape of cancer drivers and vulnerabilities
Liang, Zhao-XunGenome-guided discovery of microbial natural products
Lin, ValerieProtein post independent cell death pathways in cancer
Miao, YansongLiquid-liquid Phase Separation (LLPS)-regulated plant immunity
Phase Separation-mediated filamentous fungal growth and host invasion
Cellular Aging by Biomolecular Phase-separation
Rewiring Plant-pathogen Interactions for Novel Agrifood Technology
Mu, YuguangMachine learning approaches to improve protein-ligand binding affinity prediction
Tashiro, AyumuCharacterization of memory deficits in dementia model mice
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