Structural Biology and Drug Discovery
Description of Research Category
We are using various technologies in structural biology and biophysical
methods to decipher the relation between structure and function in
biological macromolecules.
The technologies are X-ray crystallography, NMR spectroscopy
cryo-Electron microscopy as well as biophysical techniques such as
circular dichroism, Surface plasmon resonance, Infrared spectroscopy,
calorimetry
Fluorescence spectroscopy or analytical ultracentrifugation. These
various technical platforms are used by scientists to address
fundamental questions in biology and also to discover lead compounds for
structure-based drug design.
Research Directory
Biomolecular Modeling Lab
Biomolecular Simulations and Data Analysis Lab
Cellular Biochemistry of Carbon Dioxide Fixation
Chemical-Structural Biology and Design
Chromatin Biochemistry and Biophysics
Cry-EM and Single Particle Reconstruction
Laboratory of Genomic Structural Biology
Laboratory of Molecular and Biochemical Genetics
Membrane Compartmentalisation and Cell Polarity Lab
Microbial Natural Product Biosynthesis & Bacterial Signaling Laboratory
Molecular Basis of Biosynthesis and Regulation
Peter Preiser’s Lab
Professor James P. Tam's Laboratory
Structure and Function of Molecular Engines for Drug Discovery in Infectious Diseases
Structural Biology & Drug Discovery