From Bench to
Bedside and Back

Advanced
Technologies​

Phenotyping
and Profiling

• Studying how chronic inflammation and metabolic dysfunction disrupt vascular and immune systems.​

• Illuminating subclinical vascular disease’s pathobiology by integrating cellular, molecular and physiological assessments to map early vascular dysfunctions.​

• Analysing how metabolic inflammation drives vascular dysfunction to hone diagnosis and treatments.

The team discovered that persons with fatty liver disease had three times the amount of chemokines than normal – increasing their risk to serious cardiovascular problems.

• We discovered that Covid-19 survivors may have an increased chance of blood clots, and people with underlying chronic conditions could be at higher risk.​

• We are reducing heart disease risk in diabetics using low-cost medicines through a study funded by the Tanoto Foundation.​

• We are part of a NTU team that invented ExoArc, a chip that isolates plasma from blood in a single step, and within 30 minutes, to test blood more quickly, easily and precisely for cancer biomarkers and diseases.

Endothelial function can be clinically assessed using ultrasound. This measurement, known as the flow mediated dilation, captures changes in brachial artery diameter during reactive hyperaemia, which are quantified using a dedicated edge-detection software.