An engineered nucleotidyltransferase induces cell defects in E.coli by altering metabolite levels

Tania Lupoli is currently an Associate Professor in the Department of Chemistry at New York University (NYU). Research in the Lupoli laboratory focuses on the development of molecular probes for chaperones in both human and bacterial cells, and chemical biology tools to characterize, manipulate and inhibit microbial surface glycan biosynthesis. Broadly, our laboratory seeks to understand mechanisms to perturb cellular stress response pathways and identify new therapeutic targets for the treatment of Infectious Diseases. Prof. Lupoli obtained a B.S. in Chemistry from NYU in 2005, and a Ph.D. in Chemistry from Harvard University in 2011 after performing thesis work in the laboratory of Prof. Dan Kahne. She held her first postdoctoral position in Prof Suzanne Walker’s Laboratory in the Department of Microbiology and Immunology at Harvard Medical School (2012-2013) to complete collaboratory work. She was then a Helen Hay Whitney-Simons Foundation postdoctoral fellow in the laboratory of Prof. Carl Nathan at Weill Cornell Medicine. Prof. Lupoli started her independent research group at NYU in 2018.