Cryo-Electron Microscopy Platform

The NISB Cryo-Electron Microscopy Platform at NTU for imaging biological samples was set up to support the research community in NTU and Singapore. The applications include Single Particle Analysis (SPA) of purified proteins and viruses, Cryo-Electron Tomography (Cryo-ET) of cell sections, bacterial and tissue samples, Micro Electron Diffraction (MicroED), Cryo-Focused Ion Beam (Cryo-FIB) of creating a compression-free ultra-thin cryo lamella samples for TEM tomography imaging, and Correlative Light Electron Microscope (CLEM) to image proteins inside the cell, and in isolations, using novel labeling techniques.

Equipment

Safety and facility access

User safety is one of our top priorities. As such, new users who wish to access our facilities must read through our Cryo-EM Lab Safety Rules.

Users who wish to use our instruments are required to read through our Platform Guidelines and Rules and prepare the relevant documents.

Please submit all completed documents to nisb-admin@ntu.edu.sg.

Equipment usage

Users who wish to utilize our instruments are required to book them before use. To book our instruments, please click here.
Do read through our document for EM laboratory good practices before using the equipment.

To  view our charges please click here.

For queries regarding equipment utilization, training or other matters, please contact any of our platform managers.