The Rehabilitation Research Institute of Singapore (RRIS) was established in April 2016 as a joint research institute by Nanyang Technological University, Singapore, Agency for Science, Technology and Research (A*STAR) and National Healthcare Group (NHG​). RRIS envisions becoming a world-class Asian-centric institute with focus on interdisciplinary research and innovation in science and technology for rehabilitation and assistance of human physical ability and psychosocial well-being. Strategically located in the Lee Kong Chian School of Medicine Clinical Sciences Building at the heart of the Novena Health City, RRIS serves as a focal point for scientists, engineers and clinicians to come together to co-create solutions and discovery new knowledge. The research and innovation activities at RRIS are categorized broadly into 5 thematic areas: 
(i) Ability Data; (ii) Precision Rehabilitation; (iii) Connected Ability Platform; (iv) Intelligent Assistive Technology and (v) Psychosocial Rehabilitation and Quality of Life (QoL).

RRIS is both a funding agency and a research performer. It has organized 3 rounds of Rehabilitation Research Grant to seed projects co-led by a pair of Technical and Clinical Principal Investigators from two partner institutions. The institute also hosts externally funded projects by national funding agencies and co-invested by private companies.

While the fundamental mandates of RRIS are in research and innovation, it also supports a wide spectrum of professional, educational, outreach and volunteering activities to impact the local and international community at large.

Leveraging on the strong tripartite partnership among NTU, A*STAR and NHG, RRIS is well-positioned to facilitate the organic growth of an ecosystem which synergizes all stakeholders, including healthcare providers, academic & research institutions, industry, community and the people with rehabilitation and assistive needs.