Profile Photo of SBS Faculty Rebecca Case

Assoc. Prof. Case, Rebecca Josephine

Associate Professor
Assistant Chair (Students)

Phone: (65) 6592 7942
Email: [email protected]
Personal Lab Webpage: https://www.caselabntu.com/

 

A/Prof. Rebecca Case’s research focuses on marine phototroph-bacteria interactions at the cellular and ecosystem levels. Marine ecosystems are sustained by phototrophs that feed diverse communities through photosynthesis. This organic carbon cycles from primary producers to microbes through intimate relationships within the microbial loop. Dr Case’s research focuses on the role of bioactive molecules in altering microbial interactions through changes in growth, health, fecundity and survival, and their subsequent influence on ecosystem health and function. Her field work in Singapore focuses on marine coastal communities including seagrasses, corals and algal beds. This research is complemented by her work on the model microalgal host, Emiliania huxleyi, which provides a laboratory-based system to decipher algal-bacterial interactions at the cell, gene and metabolite level. Dr Case’s team has utilised this system to identify genetic determinants of bacterial pathogenesis and host apoptosis. This system has also been adapted to other microalgae to identify and optimise production of industrially important algal metabolites for food.

Research Areas

Disease ecology, Roseobactereaceae, Phototrophs, Marine host-microbiome interactions, Ecosystem tipping points

Profile Photo of Lab Member Ananya Verma
Ananya Verma
PhD Student
Profile Photo of Lab Member Clarence Wei Hung Sim
Clarence Wei Hung Sim
Research Engineer II
Profile Photo of Lab Member Joao Pereyra
Joao Pereyra
Research Fellow
Profile Photo of Lab Member Luk Hau Ching Hannah
Luk Hau Ching
Hannah_PhD Student
Profile Photo of Lab Member Prasha Maithani
Prasha Maithani
Research Assistant
Profile Photo of Lab Member Sujatha Srinivas
Sujatha Srinivas
Research Fellow
  • Friess, D.A., Gatt, Y., Fung, T.K.T., Alemu, J., Bhatia, N., Case, R.J., Chua, S.C., Huang, D., Kwan, V., Lim, K.E., Yudhishthra, N., Ow, Y.X., Saavedra-Hortua, D., Sloey, T.M., Yando, E.S., Ibrahim, H., Koh, L.P., Puah, J.Y., Teo, S.L.M., Tun, K., Wong, L.W., and Yaakub, S.M. “Blue Carbon Science, Management and Policy across a Tropical Urban Landscape.” Landscape and Urban Planning 230 (2023): 104610.
  • Liang, K.Y.H., Orata, F.D., Boucher, Y.F., and Case, R.J. “Roseobacters in a Sea of Poly and Paraphyly: Whole Genome-Based Taxonomy of the Family Rhodobacteraceae and the Proposal for the Split of the ‘Roseobacter Clade’ into a Novel Family, Roseobacteraceae fam. nov.” Frontiers in Microbiology 12 (2021): 683109. https://doi.org/10.3389/fmicb.2021.683109
  • Bramucci, A.R., and Case, R.J. “Phaeobacter inhibens Induces Apoptosis-Like Programmed Cell Death in Calcifying Emiliania huxleyi.” Scientific Reports 9 (2019): 5215. https://doi.org/10.1038/s41598-018-36847-6
  • Labeeuw, L., Khey, J., Bramucci, A.R., Atwal, H., de la Mata, P., Harynuk, J., and Case, R.J. “Indole-3-Acetic Acid Is Produced by Emiliania huxleyi Coccolith-Bearing Cells and Triggers a Physiological Response in Bald Cells.” Frontiers in Microbiology 7 (2016): 828. https://doi.org/10.3389/fmicb.2016.00828