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The 1st Singapore Structural Biology Symposium (SSBS) is a vibrant symposium and networking platform to showcase and focus on advanced, cutting-edge research in the field of macromolecular X-ray crystallography, cryo-electron microscopy, nuclear magnetic
resonance (NMR) as well as other structural biology techniques. The symposium will feature leading local structural biologists and young, aspiring researchers.
The symposium will be held on the 24th and 25th of May 2022, at the School of Biological Sciences, NTU. Registration for participation is open and FREE to all local institution staff and students. The registration period is between 25th March 2022 to 25th April 2022. For enquiries, contact Ms. Lynette Liew drop us an E-mail.
Registration is closed
Poster Abstract Submissions
The SSBS organizing committee would like to invite prospective authors to submit their abstracts for a poster presentation. The topic of the poster should be based on using structural biology methods to address key scientific questions.
Please submit your poster abstracts to [email protected] with the E-mail subject "Poster Abstract", by no later than 25th April 2022.
Please include in the email:
- Your name
- Your home institute
- An abstract not exceeding 250 words.
Speakers
- BABURAJENDRAN, Nithya | EDDC, A*STAR
- BASAK, Sandip | SBS, NTU
- BHUSHAN, Shashi | SBS, NTU
- BROWN, Christopher | IMCB, A*STAR
- GAO, Yonggui | SBS, NTU
- GRÜBER, Gerhard | SBS, NTU
- KANG, Congbao | EDDC, A*STAR
- LESCAR, Julien | SBS, NTU
- LOK, Sheemei | Duke-NUS
- LU, Gan | DBS, NUS
- LUO, Ming | DBS, NUS
- MIRSAIDOV, Utkur | DP, NUS
- MU, Yuguang | SBS, NTU
- NORDENSKIÖLD, Lars | SBS, NTU
- SIVARAMAN, Jayaraman | DBS, NUS
- SONG, Haiwei | IMCB, A*STAR
- TAN, Yong Zi | DBS, NUS
- VENKITARAMAN, Ashok | CSI, NUS
- VERMA, Chandra | BII, A*STAR
- WAN, Yue | GIS, A*STAR
- WU, Bin | SBS, NTU
- XU, Weijun | EDDC, A*STAR
- XUE, Kai | SPMS, NTU
- YANG, Daiwen | DBS, NUS
SSBS Program
Session I | |
| 8:30 AM | Registration |
| 9:00 AM | Opening addresses |
| 9:20 AM | Assoc. Prof. LUO Dahai and Dr. CHEW, Bing Liang Alvin Lee Kong Chian School of Medicine, NTU |
| Secreted dengue virus NS1 is predominantly dimeric and in complex with high-density lipoprotein | |
| 9:40 AM | Prof. YANG Daiwen Department of Biological Sciences, NUS |
| Impact of Transient Protein-Membrane Interactions on Protein Conformational Exchange Probed by NMR relaxation | |
| 10:00 AM | Prof. LOK Sheemei Duke-NUS Medical School |
| CryoEM structures of the multimeric secreted NS1, a major factor for dengue hemorrhagic fever | |
| 10:20 AM | Prof. VENKITARAMAN Ashok Cancer Science Institute, NUS |
| Structural regulation of DNA recombination by the BRCA2 cancer suppressor and its targeting by small molecules | |
| 10:40 AM | Prof. NORDENSKIÖLD Lars School of Biological Sciences, NTU |
| The structure and dynamics of human telomeric chromatin suggests mechanisms for telomere maintenance | |
| 11:00 AM | Tea Break & Poster Session |
| 12:00 PM | Open Dialogue–The Initiation of Singapore Structural Biology Consortium Panel members: Prof. LIM Kah Leong (LKC, NTU), Prof. LIOU Yih-Cherng (DBS, NUS), Prof. NORDENSKIÖLD Lars (SBS, NTU), Prof. O’CONNELL Damian (EDDC, A*STAR), Prof. PHANAnh Tuan (NISB, NTU), Dr. SONG Haiwei (IMCB, A*STAR), Prof. VENKITARAMAN Ashok (CSI, NUS), Prof. YANG Daiwen (DBS, NUS) |
| 12:30 PM | Lunch & Poster Session |
Session II | |
| 2:00 PM | Prof. SIVARAMAN Jayaraman
Department of Biological Sciences, NUS |
| Structural basis for the neutralization of Hepatitis E virus and the role of mosquito procarboxypeptidase in viral infection | |
| 2:20 PM | Dr. KANG Congbao Experimental Drug Development Centre, A*STAR |
| Applications of solution NMR spectroscopy in target-based drug discovery | |
| 2:40 PM | Assoc. Prof. MU Yuguang School of Biological Sciences, NTU |
| A new machine learning score function for virtual screening: through decoy poses learning | |
| 3:00 PM | Asst. Prof. TAN Yong Zi Department of Biological Sciences, NUS |
| Addressing Preferred Orientation in Single-Particle Cryo-EM Through Tilting | |
| 3:20 PM | Coffee Break |
| 3:35 PM | Dr. BABURAJENDRAN Nithya Experimental Drug Development Centre, A*STAR |
| X-ray crystallography: ‘microscope’ of the drug discovery world | |
| 3:55 PM | Asst. Prof. BHUSHAN Shashi School of Biological Sciences, NTU |
| Conformational changes in the selectivity filter underlie C-type inactivation in human potassium ion channel Kv1.3 | |
| 4:15 PM | Dr. BROWN Christopher Institute of Molecular and Cell Biology, A*STAR |
| Biological Inspired Lead Design with Genetically Encoded Libraries | |
| 4:35 PM | Dr. EL SAHILI Abbas School of Biological Sciences, NTU |
| Structural basis for substrate recognition and ligation by asparaginyl peptide ligases |
Session I | |
| 9:00 AM | Prof. GRÜBER Gerhard School of Biological Sciences, NTU |
| Complementary structural tools to discover new targets and compounds of pathogenic mycobacteria | |
| 9:20 AM | Dr. VERMA Chandra Bioinformatics Institute, A*STAR |
| The role of computational models in modern biology: some stories from the Bioinformatics Institute | |
| 9:40 AM | Assoc. Prof. WU Bin School of Biological Sciences, NTU |
| TIR domains of plant immune receptors are sensors of intracellular dsDNA/RNA mediating cell death | |
| 10:00 AM | Dr. SONG Haiwei Institute of Molecular and Cell Biology, A*STAR |
| Structural and functional insights into DNA unwinding mechanism of Pif1 helicase | |
| 10:20 AM | Coffee Break |
| 10:35 AM | Assoc. Prof. MIRSAIDOV Utkur Department of Physics, Material Science, and Biological Sciences, NUS |
| How do crystals form from a solution? A glimpse at nonclassical nucleation process with in situ TEM | |
| 10:55 AM | Assoc. Prof. GAO Yonggui School of Biological Sciences, NTU |
| Molecular basis of cellulose biosynthesis | |
| 11:15 AM | Assoc. Prof. LU Gan Department of Biological Sciences, NUS |
| Heterogeneous non-canonical nucleosomes predominate in yeast cells in situ | |
| 11:35 AM | Lunch and Poster Session |
Session II | |
| 2:00 PM | Asst. Prof. BASAK Sandip School of Biological Sciences, NTU |
| Cryo-EM reveals the gating and drug modulation in ligand-gated ion channels | |
| 2:20 PM | Dr. CHEN Ming Wei School of Biological Sciences, NTU |
| Design, evaluation, and production of recombinant protein constructs at the NTU Protein Production Platform. | |
| 2:40 PM | Asst. Prof. LUO Min Department of Biological Sciences, NUS |
| Structure Basis for RNA-guided DNA targeting and degradation in Type 1 CRISPR-Cas system | |
| 3:00 PM | Coffee Break |
| 3:15 PM | Dr. XU Weijun Experimental Drug Development Centre, A*STAR |
| Structural model of human PORCN illuminates disease-associated variants and drug-binding sites | |
| 3:35 PM | Dr. XUE Kai School of Physical and Mathematical Sciences, NTU |
| Recent development in solid state NMR and a few applications in biosolids | |
| 4:10 PM | Dr. SER Zheng
Institute of Molecular and Cell Biology, A*STAR |
| Cross-linking mass spectrometry-based structural analysis of the Smc5/6 complex | |
| 4:25 PM | Dr. SOMAN, Aghil
School of Biological Sciences, NTU |
| Cryo-EM structure of the telomerictetranucleosome-A new paradigm in DNA packaging? | |
| 4:40 PM | Best Poster Announcement |
| 4:50 PM | Closing Remarks |
Location and Date
Address
School of Biological Sciences
Nanyang Technological University
60 Nanyang Drive, SBS CR-1
Singapore 637551
Show Location
Date
24th May to 25th May
Contact
Ms. Lynette Liew Sin Yee
Tel: +65 6908 2219
Email: [email protected]
NTU Institute of Structural Biology
https://www.ntu.edu.sg/nisb
Health Declaration (Mandatory)
As per NTU Policy, from 1 January 2022, only business-related visitors who are
(i) Fully vaccinated,
(ii) Medically exempted, or
(iii) Have recovered from COVID-19 in the last 180 days,
will be allowed to be present on campus, in compliance
with the national guidelines.
- Unvaccinated visitors will not be allowed to enter campus venues.
- Visitors must be pre-registered and submit their health declaration form at least one day before their visit.
Please fill in the following fields in the declaration form as follows:
Organized by
In partnership with
Organizing Committee
- PHAN, Anh Tuan | NISB, NTU (Chair)
- GAO, Yonggui | SBS, NTU
- LESCAR, Julien | SBS, NTU
- LIEW, Chong Wai | NISB, NTU
- LIM, Wan Hsin | EDDC, A*STAR
- LIOU, Yih-Cherng | DBS, NUS
- LUO, Dahai | LKC, NTU
- NORDENSKIÖLD, Lars | SBS, NTU
- SIVARAMAN, Jayaraman | DBS, NUS
- SONG, Haiwei | IMCB, A*STAR
- VERMA, Chandra | BII, A*STAR
- YANG, Daiwen | DBS, NUS
Sponsored by
