Brain Bank Singapore

Research Focus

The tissues preserved in the snap-frozen form allow for extensive molecular investigation, including using “Omics” platforms:

  • Gene polymorphism sequencing
  • Epigenetics
  • Single-nuclear RNA sequencing
  • microRNA (miRNA) sequencing
  • Protein arrays
  • Immunoassays
  • Immunohistochemistry
  • Metabolite spectrometry
  • Drug library validation

Some tissue blocks are also preserved in the form of formalin-fixed and paraffin wax-embedded specimens which are useful for histological analysis of disease pathology. Other types of tissues, where available, can include spinal cord, peripheral nerves, muscle, gut, spleen and lymph nodes.

Mask Group (58)

Tissue Access Committee

Requests for tissues are examined strictly and transparently by an Access Committee that comprises scientists from multiple research institutions nationally. The study protocols submitted for tissue requests will need to be compliant with the Human Biomedical Research Act (HBRA). No restricted research involving the combination of human and animal components is allowed for any study.

BBS Tissue request form_17 Oct 2019 (pdf)
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Please contact the Brain Bank Singapore to determine the availability of tissues before completing the Tissue Request Form.

Please note that researchers who are interested in applying for the use of these post-mortem tissues will need to have Institutional Review Board (IRB) ethics approval for human tissue biomedical research in place before any tissue can be shipped.
UK MRC Brain Bank Network Database

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