Structural Biology and Drug Discovery

Description of Research Category

We are using various technologies in structural biology and biophysical methods to decipher the relation between structure and function in biological macromolecules.

The technologies are X-ray crystallography, NMR spectroscopy cryo-Electron microscopy as well as biophysical techniques such as circular dichrois​m, Surface plasmon resonance, Infrared spectroscopy, calorimetry

Fluorescence spectroscopy or analytical ultracentrifugation. These various technical platforms are used by scientists to address fundamental questions in biology and also to discover lead compounds for structure-based drug design.

Research Directory

Biomolecular Modeling Lab
Biomolecular Simulations and Data Analysis Lab
Cellular Biochemistry of Carbon Dioxide Fixation
Chemical Biology, Biotechnology & Drug Discovery
Chemical-Structural Biology and Design
Chromatin Biochemistry and Biophysics
Cry-EM and Single Particle Reconstruction
Laboratory of Genomic Structural Biology
Insect olfactory receptors & single particle Cryo-EM
Laboratory of Molecular and Biochemical Genetics
Membrane Compartmentalisation and Cell Polarity Lab
Microbial Natural Product Biosynthesis & Bacterial Signaling Laboratory
Molecular Basis of Biosynthesis and Regulation
Peter Preiser’s Lab
Professor James P. Tam's Laboratory
Structure and Function of Molecular Engines for Drug Discovery in Infectious Diseases
Wu Bin’s Lab
Xiao Tianshu's Lab