List of Ph.D. Projects Available

The application deadline for Ph.D. projects is as follows:
 
August intake: 31 January
January intake: 31 July
 
Apply online via NTU website here.
 
Email your application ID to ac-sbs-gs@ntu.edu.sg, so that we can facilitate the application process.
 
If you have any queries, please write to ac-sbs-gs@ntu.edu.sg
 
The following table lists the Ph.D. projects that are currently available. 
Click on the individual links to find out more about each research project. You may contact the research supervisor directly if you have any questions regarding the project you are interested in. 
SupervisorResearch Project Title
Bhattacharyya, Suraji​​tDesign and mode of action of antimicrobials (peptides and mimetics) and mechanisms of bacterial resistance
Designing Functional Mini-proteins
Mechanisms of Integrins Mediated Cell-Cell Adhesion & Therapeutics Development​
Ch’ng, Toh Hean*​Neurobiology of Learning and Memory
Synapse-to-nucleus signaling and transcription-dependent plasticity in neurodegenerative disorders
The role of astrocytes during learning and memory​
​Chen, Albert I-Ming​Defining the functional organization of cerebellar output circuits involve in motor and non-motor behaviors
​Choe, Young-Jun ​Quality control mechanisms of incomplete nascent proteins
​Quality control of stalled proteins in human cells
Roca, Francesc Xavier Splicing mechanisms and their alterations in human genetic diseases
Fullwood, MelissaUnderstanding 3D genome organization in cancer through an integrated artificial intelligence and molecular biology approach​
Gao, YongguiStructure and function of ribosome and drug design; Glycobiology towards Biofuel; Pathogen virulence
​Goh, WilsonMissing protein prediction using networks​
Kline, KimberlyFormation and function of membrane lipid microdomains in Enterococcus faecalis​
Mechanisms of E. faecalis Subversion of Neutrophil-mediated killing​
Mechanisms of E. faecalis Immune Modulation in Macrophages​
The lipidomics of Enterococcus faecalis infection
Koh, Cheng GeeCancer Microenvironment and its Impact on the Biology of Cancer Cells​
Functional Relationship between Actin Cytoskeleton Regulation and Cell Cycle Progression 
Regulation of embryonic stem cell pluripotency and differentiation by biochemical and biophysical cues
Lescar, JulienThe L protein from the Respiratory Syncytial Virus: Structures and functions
Liang, Zhao-Xun ​Genome-guided discovery of marine natural products
Production of cannabinoids and other natural products using microbial hosts 
Li, Hoi Yeung ​Application of 3D culture to investigate somatic cells reprogramming, cancer development and various cellular events​
Investigation on the molecular mechanism and physiological roles of AAA-ATpase p97/VCP in cancer metastasis
​Multidisciplinary approach to redefine chromosome condensation models
Li, YinghuiCharacterizing the regulatory landscape of cancer drivers and vulnerabilities
Epigenetic regulation of NF-κB in cancers
Role of MAPK signaling in chromatin organization and transcriptional control of cancers
Lu, LanyuanInvestigating the protein phase behavior in polarized fungal growth by coarse-grained molecular simulation​
Lu, LeiHow proteins are targeted to cilia
The dynamic trafficking within the Golgi
The effect of nutrient on the membrane trafficking
​Ludwig, Alexander ​ ​Structure and higher-order organisation of caveolae studied by correlative light and electron microscopy
​Ma, Wei​Functional characterization of transcriptional regulator(s) in plant oil biosynthesis and plant development​
Miao, YansongLiquid-liquid Phase Separation(LLPS)-regulated plant immunity
Mechanistic studies of LLPS-mediated actin assembly via reconstitution
Cellular aging regulation by cytoskeleton
​Defence mechanisms of plant for pathogen infection
Mitra, RupshiIndividual difference in stress coping: A possible brain mechanism
Stress manifestation and its implications in primate society
Mu, Yuguang​ ​Improved computational models for peptide/HLA interactions with T cells and natural killer cells
​Improve protein-ligands docking scoring using machine learning method.
Understanding off-target effects of CRISPR/Cas9 using molecular dynamics simulations​
Mueller-Cajar, OliverMechanistic studies concerning biological CO2 fixation
Microalgal CO2 superchargers
Mutwil, MarekElucidating adaptive mechanism conferring resilience to environmental stress in plants
Identifying biosynthetic pathways for high-value compounds
Nordenskiöld, LarsBiochemical and biophysical investigations of structural and dynamic properties of telomeric chromatin and nucleosomes
Multi-Scale Simulations of Biomolecular Self-Assembly by Inverse Monte Carlo
Solid State NMR on chromatin
Pervushin, KonstantinMechanism of chaperone function of prostaglandin synthase for amyloid b-peptides
​​Preiser, Peter​ ​ ​ ​Small variant antigens of malaria parasites as key regulators of biological functions
The plasmodium parasite exported protein interactome inside the host erythrocyte
​The role of RNA modifications in malaria parasite biology​
Ruedl, ChristianeCross-talk between resident macrophages and adipose tissue in obesity: searching for culprits
Sanyal, AmartyaUnderstanding chromatin and epigenetic basis of gene regulatory landscape in development and disease
Salojärvi, ​Jarkko​Adaptive radiation following the loss of a root symbiont​
Bhushan, Shashi Structural and biochemical studies of Mycobacterial biosynthetic enzymes
Structural and biochemical studies of Mycobacterial drug transporters 
Structural analysis of drug binding on Potassium Channels
Su, I-HsinFunctional characterization and physiological significance of SETD3-mediated methylation in immune responses
Molecular and functional characterization of UBR7-regulated cell adhesion and migration
The role of cytoplasmic EZH2 in cancer stem cells 
​​The role of dendritic cells in T cell development and thymic involution
Surgrue, RichardDevelopment of a vaccine candidate for EMCV
Evaluation of 3D cell culture systems for use as bioreactors in production for vaccine development and isolation of viruses from clinical specimens
Host pathogen interactions with the influenza virus polymerase complex​
Signalling pathways that mediate respiratory syncytial virus morphogenesis 
Sze, Siu Kwan NewmanElucidating epigenetic regulation in food/diet induced obesity and metabolic syndrome
Hypoxia-sensitive epigenetic regulators (HYSERs) as novel targets for the treatment of solid tumors
Pre-clinical development of a cancer immunotherapy targeting tumor exosomal proteins
Translational biomarker research for prediction of diabetic vascular complications in diabetes mellitus patients
​​ Translational biomarker research to identify silent vulnerable patient at risk of major adverse cardiovascular events​ ​​
Tan, Suet MienInvestigating integrin-linked cell adhesion-mediated drug resistance in leukemic cells
Investigating the roles of kindlins in cancer epithelial-mesenchymal transition
Tashiro, AyumuElectrophysiological investigation of the function of new neurons in adult hippocampus
Molecular mechanisms underlying experience- and activity-dependent regulations of adult neurogenesis
Roles of astrocyte-neuron signaling in neuronal information processing in the hippocampus
Thanabalu, ThirumaranMolecular characterization of Cancer resistance in Atopic Dermatitis mice (Skin Research Scholarship)
Identification of the molecular mechanism of long hair phenotype in triple transgenic mice (Skin Research Scholarship)
Role of N-WASP in Squamous Cell Carcinoma (Skin Research Scholarship)​
Thibault, GuillaumeCellular Stress Response in Metabolic Syndrome
The role of the endoplasmic reticulum in age-related macular degeneration (AMD)
Dissecting synergetic outcome of host-microbe interactions in wound of diabetic animal models
Dissect an essential human cellular stress pathway by synthetic biology
Vyas, AjaiBehavioral manipulation of the host by the parasites
Non-consumptive effects of predation
Yoon, Ho Sup JoeNR4A Nuclear Receptors in Insulin Signaling and Fatty Liver Diseases
​​​​​* PhD projects not available for Research Student Scholarships from SBS-NTU​