Adjunct Professor Jodhbir Singh Mehta

Distinguished Professor, Clinical Innovation in Ophthalmology
Head, Corneal and External Eye Disease Department
Senior Consultant, Refractive Service Department
Senior Consultant, Cataract & Comprehensive Ophthalmology Department
Singapore National Eye Centre (SNEC)

Deputy Executive Director
Singapore Eye Research Institute (SERI)
Current Research Interests
Prof Jodhbir Mehta conducts laboratory, translational and clinical research related to selective tissue transplantation particularly pertaining to the cornea. His laboratory-based research projects involve investigating the potential of stem cells for human corneal endothelial cell proliferation and studies on patients with corneal genetic disorders. His corneal interests lie in corneal transplantation – penetrating keratoplasty, lamellar keratoplasty and endothelial keratoplasty, femtosecond laser technology, corneal imaging, corneal infections, corneal refractive surgery, keratoprosthesis surgery, ocular drug delivery systems and corneal genetics.

The majority of his laboratory-based work is in translational research and focuses on the use of femtosecond lasers, ocular surface reconstruction, development of artificial cornea, corneal wound healing, protein aggregation diseases and corneal drug delivery systems. His clinical based research involves research into imaging devices for the cornea, case comparative cohorts of new selective tissue transplantation procedures compared to penetrating keratoplasty, examining complications and outcomes of these new procedures. 

Biographical Information
Prof Mehta is Distinguished Professor of Clinical Innovation in Ophthalmology, Singapore National Eye Centre (SNEC). He holds concurrent appointments as Deputy Executive Director of the Tissue Engineering and Stem Cell Group at Singapore Eye Research Institute (SERI) and Head of the Corneal and External Eye Disease Department and Senior Consultant of the Refractive Service and Cataract & Comprehensive Ophthalmology departments in SNEC. He has academic affiliations with MSE, NTU Singapore and DUKE-NUS Medical School. He is also on the Executive Committee for the International Society of Refractive Surgeons (ISRS) (AAO) and sits on the Board of Directors for the US Corneal Society. To date, he has authored >400 peer-reviewed publications, >20 academic textbooks, and given >220 oral and poster presentations. His research work has developed 14 patents, of which 4 have been commercialized and licensed to companies. He has also won 52 national and international awards, including those at the American Academy of Ophthalmology (AAO) and the Association for Research in Vision and Ophthalmology (ARVO).

Selected Publications (recent 10)

1. “Role of anterior segment optical coherence tomography angiography in the assessment of acute chemical ocular injury: a pilot animal model study”. Scientific Reports (2021), 11:16625. Kai Yuan Tey, Jinyuan Gan, Valencia Foo, Bingyao Tan, Meng Yuan Ke, Leopold Schmetterer,Jodhbir S. Mehta, & Marcus Ang

2. “Safety profiles of terahertz scanning in ophthalmology”. Scientific Reports (2021), 11:2448. Yu-Chi Liu, Lin Ke, Steve Wu Qing Yang, Zhang Nan, Ericia Pei Wen Teo, Nyein Chan Lwin, Molly Tzu-Yu Lin, Isabelle Xin Yu Lee, Anita Sook-Yee Chan, Leopold Schmetterer, & Jodhbir S. Mehta

3. “Epithelial and stromal remodelling following femtosecond laser–assisted stromal lenticule addition keratoplasty (SLAK) for keratoconus”. Scientific Reports (2021), 11:2293. Mario Nubile, Niccolò Salgari, Jodhbir S. Mehta, Roberta Calienno, Emanuele Erroi, Jessica Bondi, Manuela Lanzini, Yu-Chi Liu, & Leonardo Mastropasqua

4. “A pilot study investigating anterior segment optical coherence tomography angiography as a non-invasive tool in evaluating corneal vascularisation”. Scientific Reports (2021), 11:1212. Hon Shing Ong, Kai Yuan Tey, Mengyuan Ke, Bingyao Tan, Jacqueline Chua, Leopold Schmetterer, Jodhbir S. Mehta, & Marcus Ang

5. “Recent Advances in Pediatric Endothelial Keratoplasty”. International Ophthalmology Clinics (2021), 61(1), 57-75. Moushmi Patil, Yu Qiang Soh, Howard Cajucom-Uy Yu, Ken Nischal, &Jodhbir S. Mehta

6. “New Therapies for Corneal Endothelial Diseases: 2020 and Beyond”. Cornea (2021), 40(11), 1365-1373. Yu Qiang Soh, Stanley S. J. Poh, Gary S. L. Peh, & Jodhbir S. Mehta

7. “Corneal neuromediator profiles following laser refractive surgery”. Neural Regeneration Research (2021), 16(11), 2177-2183. Lily Wei Yun Yang, Jodhbir S Mehta, & Yu-Chi Liu

8. “Human platelet lysate as a replacement for fetal bovine serum in human corneal stromal keratocyte and fibroblast culture”. Journal of Cellular and Molecular Medicine (2021), 25(20), 9647-9659. Nina Seidelmann, Daniela F. Duarte Campos, Malena Rohde, Sandra Johnen, Sabine Salla, Gary HARVIN-Fai Yam, Jodhbir S. Mehta, Peter Walter, & Matthias Fuest

9. “Automatic segmentation of corneal deposits from corneal stromal dystrophy images via deep learning”. Computers in Biology and Medicine (2021), 137, 104675. Mihir Deshmukh, Yu-Chi Liu, Tyler Hyungtaek Rim, Anandalakshmi Venkatraman, Matthew Davidson, Marco Yu, Hong Seok Kim, Geunyoung Lee, Ikhyun Jun, Jodhbir S. Mehta, & Eung Kweon Kim

10. “Cosmetic Contact Lens-Related Corneal Infections in Asia”. American Journal of Ophthalmology (2021), 229, 176-183. Fiona Stapleton, Chris H. L. Lim, Suhyun Kweon, Donald Tan, & Jodhbir S. Mehta